{"id":8335,"date":"2020-06-17T11:44:26","date_gmt":"2020-06-17T09:44:26","guid":{"rendered":"https:\/\/primaderma.ro\/?page_id=8335"},"modified":"2020-06-17T11:44:26","modified_gmt":"2020-06-17T09:44:26","slug":"asist-univ-dr-radu-antonia","status":"publish","type":"page","link":"https:\/\/pdi.ro\/2020\/asist-univ-dr-radu-antonia\/","title":{"rendered":"Asist. Univ. Dr. Radu Antonia"},"content":{"rendered":"

[et_pb_section fb_built=”1″ fullwidth=”on” disabled_on=”on|off|off” _builder_version=”3.22″ custom_margin=”||” custom_padding=”15px||29px” top_divider_style=”waves2″ top_divider_color=”#f0622a” top_divider_flip=”horizontal|vertical” bottom_divider_style=”waves2″ bottom_divider_color=”#fcdedb” bottom_divider_height=”105px” bottom_divider_flip=”vertical” collapsed=”off”][et_pb_fullwidth_header title=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF90aXRsZSIsInNldHRpbmdzIjp7ImJlZm9yZSI6IiIsImFmdGVyIjoiIn19@” text_orientation=”right” header_image_url=”https:\/\/pdi.ro\/2020\/wp-content\/uploads\/2020\/05\/pdi_iulie_online.png” disabled_on=”on|on|off” _builder_version=”4.4.7″ _dynamic_attributes=”title” title_font=”Kaushan Script||||||||” title_text_align=”right” title_text_color=”#f0622a” title_font_size=”50px” content_font=”|600||on|||||” content_text_align=”center” content_text_color=”#686766″ content_font_size=”15px” subhead_font=”||||||||” background_color=”rgba(239,145,107,0.54)” background_image=”https:\/\/pdi.ro\/2020\/wp-content\/uploads\/2020\/02\/back.jpg” background_layout=”light” custom_margin=”0px||8px” custom_padding=”40px||40px||true” content_font_size_tablet=”” content_font_size_phone=”15px” content_font_size_last_edited=”on|desktop”][\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22″ locked=”off”][et_pb_row column_structure=”2_5,3_5″ _builder_version=”3.25″][et_pb_column type=”2_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/pdi.ro\/2020\/wp-content\/uploads\/2020\/06\/Radu-Antonia.png” align=”center” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.4.8″ max_width=”31%” hover_enabled=”0″ border_radii=”on|100px|100px|100px|100px” title_text=”Radu Antonia”][\/et_pb_image][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ hover_enabled=”0″]<\/p>\n

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Asist. Univ. Dr. Radu Antonia<\/span><\/strong>
Universitatea de Medicin\u0103 \u015fi Farmacie din Craiova<\/span><\/strong><\/h4>\n

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Analiza imunohistochimica a produsului de peroxidare lipidic\u0103 \u00een leziunile melanocitare<\/span>
Autori: Antonia Radu, Cornelia Bejenaru, I. \u0162olea, Daciana Elena Br\u0103ni\u015fteanu<\/span><\/p>\n

Scopul acestui studiu a fost analiza comparativ\u0103 din punct de vedere imunohistochimic a 4-hidroxi-2-nonenalului \u00een diferite leziuni melanocitare, pentru a eviden\u021bia importan\u021ba acestui biomarker \u00een melanom. Am utilizat \u021besut de la 45 de pacien\u021bi, cuprinz\u00e2nd: 5 nevi comuni, 5 nevi displazici, 25 de melanoame primare \u0219i 10 metastaze. Am aplicat metoda imunohistochimic\u0103 \u00een 2 timpi, specific\u0103 pentru polimeri, pentru a marca epitopii de interes. Imunomarcajul a fost f\u0103cut cu anticorpul anti-4-hidroxi-2-nonenal \u0219i s-a determinat intensitatea acestuia \u0219i procentajul de celule pozitive. Imunoexpresia 4-hidroxi-2-nonenalului este considerabil crescut\u0103 at\u00e2t \u00een melanoame, c\u00e2t \u0219i \u00een nevii displazici, comparativ cu nevii comuni \u0219i apare \u00een stadiile timpurii ale melanogenezei, lu\u00e2nd \u00een considerare prezen\u021ba sa \u00een tumorile primare \u0219i absen\u021ba \u00een cele metastatice.<\/p>\n

Immunohistochemical analysis of lipid peroxidation product in melanocytic lesions<\/span>
Authors: Antonia Radu, Cornelia Bejenaru, I. \u0162olea, Daciana Elena Br\u0103ni\u015fteanu<\/span><\/p>\n

The aim of this research was to do a comparative immunohistochemical evaluation of 4-hydroxy-2-nonenal in different melanocytic lesions, in order to emphasize the significance of this biomarker in melanoma. We utilized tissue harvested from 45 patients, comprising: 5 common nevi, 5 dysplastic nevi, 25 primary melanomas and 10 metastases. We applied the two-time polymer-specific immunohistochemical method to label the epitopes of interest. We performed immunostaining with anti-4-hydroxy-2-nonenal antibody and determined the staining intensity and the percentage of positive cells. The immunoexpression of 4-hydroxy-2-nonenal is considerably elevated in both cutaneous melanomas and dysplastic nevi versus common nevi and occurs early in melanomagenesis, considering its presence in primary tumors and its lack in metastatic ones.<\/p>\n

Scurt CV<\/span><\/p>\n

Studii:<\/strong>
Universitare:
▪ Facultatea de Drept \u015fi \u015etiin\u0163e Administrative, Universitatea din Craiova \/ Law University Degree 2012
▪ Facultatea de Farmacie, Universitatea de Medicin\u0103 \u015fi Farmacie din Craiova \/ Pharmacy University Degree 2013
Postuniversitare:
\u2013 Specialitate \u201eDrept Privat\u201d, Facultatea de Drept \u015fi \u015etiin\u0163e Administrative, Universitatea din Craiova \/ Law Master\u2019s Degree 2013
\u2013 Specialitate \u201eFarmacologie \u015fi Toxicologie\u201d, Facultatea de Farmacie, UMF din Craiova \/ Pharmacy Master\u2019s Degree 2014<\/p>\n

Experien\u0163\u0103 profesional\u0103:<\/strong>
2013-prezent: Farmacist Diriginte, SC Izvorul Tamaduirii Biovita SRL \/ leading pharmacist
2018-prezent: Asistent Universitar Dr., disciplina Botanica Farmaceutica, Facultatea de Farmacie, UMF Craiova \/ University Assistant<\/p>\n

Proiecte de cercetare:<\/strong>
2014-2015: POSDRU\/159\/1.5\/S\/133377, titlu: \u201eProbleme de diagnostic \u00een melanomul malign \u2013 implica\u021bii terapeutice”
2016-2017: UMF Craiova, titlu: “Evaluarea in vitro a efectului acidului salicilic asupra tumorilor cerebrale”<\/p>\n

Membru al unor societ\u0103\u0163i \u015ftiin\u0163ifice la nivel na\u021bional:<\/strong>
▪ Societatea de \u015etiin\u0163e Farmaceutice din Rom\u00e2nia
▪ Societatea Rom\u00e2n\u0103 de Istoria Farmaciei
▪ Societatea Rom\u00e2n\u0103 de Biologie Celular\u0103
▪ Societatea Rom\u00e2n\u0103 de Biochimie \u015fi Biologie Molecular\u0103
▪ Societatea Rom\u00e2n\u0103 de Dermatologie<\/p>\n

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Contacteaz\u0103 operatorul PDI 2020<\/p>\n

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Operatorul PDI 2020<\/p>\n

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\"\"<\/span><\/p>\n

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Adresa: Str. A. Panu nr. 13, Iasi<\/span>
Tel.: 0332.40.88.00-05<\/span>
E-mail: inscrieri@primaderma.ro<\/a>
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Asist. Univ. Dr. Radu AntoniaUniversitatea de Medicin\u0103 \u015fi Farmacie din CraiovaAnaliza imunohistochimica a produsului de peroxidare lipidic\u0103 \u00een leziunile melanocitare Autori: Antonia Radu, Cornelia Bejenaru, I. \u0162olea, Daciana Elena Br\u0103ni\u015fteanu Scopul acestui studiu a fost analiza comparativ\u0103 din punct de vedere imunohistochimic a 4-hidroxi-2-nonenalului \u00een diferite leziuni melanocitare, pentru a eviden\u021bia importan\u021ba acestui biomarker \u00een […]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-8335","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/pages\/8335","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/comments?post=8335"}],"version-history":[{"count":3,"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/pages\/8335\/revisions"}],"predecessor-version":[{"id":8339,"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/pages\/8335\/revisions\/8339"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/media?parent=8335"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}