<\/strong><\/span><\/h5>\n<\/strong><\/span><\/h5>\n<\/strong><\/span><\/h5>\n<\/strong><\/span><\/h5>\nProf. Dr. Zurac Sabina<\/strong><\/span>
\nUniversitatea de Medicin\u0103 \u015fi Farmacie \u201cCarol Davila\u201d Bucure\u015fti
\n Spitalului Clinic Colentina, Bucure\u0219ti
\n<\/strong><\/span><\/h5>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”3.25″ locked=”off”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ hover_enabled=”0″]<\/p>\n
Aspecte lezionale identificate necroptic \u00een COVID-19. Experien\u0163a Spitalului Clinic Colentina<\/span>
\n Autori: Sabina Zurac, Luciana Nichita, Cristiana Popp, Mirela Cioplea, Alexandra Bastian, Lelia Iliescu, Ioana Simion<\/span><\/p>\nApari\u021bia unui nou patogen ridic\u0103 \u00eentotdeauna \u00eentreb\u0103ri asupra modalit\u0103\u021bilor prin care acesta determin\u0103 leziuni \u00een organismul uman, r\u0103spunsul evident fiind efectuarea de autopsii la persoanele care decedeaz\u0103 de aceast\u0103 boal\u0103. Necesitatea identific\u0103rii substratului morfopatologic al leziunilor \u00een COVID-19 este evident\u0103 dar trebuie evaluate cu aten\u021bie condi\u021biile \u00een care se efectueaz\u0103 autopsiile, fiind necesare s\u0103li de autopsie cu circuite func\u021bionale care s\u0103 asigure protec\u021bia personalului care efectueaz\u0103 autopsia \u0219i care s\u0103 previn r\u0103sp\u00e2ndirea accidental\u0103 a virusului. Av\u00e2nd \u00een vedere aceste considerente, precum \u0219i prevederile legale \u00een vigoare (evaluarea atent\u0103 a fiec\u0103rui caz de deces cu infec\u021bie SARS-Cov2 \u0219i posibilitatea de efectuare de autopsii \u00een scop \u0219tiin\u021bific pe baza unui proiect de cercetare aprobat de Comisia de Etic\u0103 a institu\u021biei), \u00een Spitalul Clinic Colentina am efectuat \u00een decurs de o lun\u0103 4 autopsii la deceda\u021bi cu COVID-19.
\nAntecedentele personale patologice ale deceda\u021bilor identific\u0103 \u00eentre comorbidit\u0103\u021bi cel mai frecvent hipertensiunea arterial\u0103, fibrila\u021bia atrial\u0103 \u0219i diabetul zaharat de tip 2. Trei pacien\u021bi erau supraponderali f\u0103r\u0103 s\u0103 fie obezi. O pacient\u0103 asocia concomitent \u0219i infec\u021bie cu virus gripal B.
\nTabloul lezional al deceda\u021bilor cu COVID 19 autopsia\u021bi a fost relativ similar, predomin\u00e2nd leziunile vasculare de ordin trombotic cu apari\u021bia fie a trombemboliei pulmonare \u00eentr-un caz, fie a infarctelor pulmonare (\u00een toate cazurile), splenice (2 cazuri) sau suprarenaliene (2 cazuri) \u0219i leziunile miocardice (miocardit\u0103 intersti\u021bial\u0103 \u00een toate cazurile \u0219i leziuni distrofice miocardice \u00een 2 cazuri). Trei deceda\u021bi au prezentat afectare alveolar\u0103 difuz\u0103 (substratul morfologic al sindromului de detres\u0103 respiratorie a adultului) grad I (un caz) \u0219i grad I-II (2 cazuri) iar \u00een dou\u0103 cazuri au fost identificate \u015fi mici focare diseminate, bilaterale, de bronhopneumonie. To\u021bi pacien\u021bii au prezentat miocardoscleroz\u0103 ca leziuni miocardice preexistente. Toate cazurile au prezentat steatoz\u0103 hepatic\u0103 (macro\/medio\/microvacuolar\u0103 2 cazuri, macrovacuolar\u0103 un caz, microvacuolar\u0103 un caz) \u0219i deple\u0163ie limfoid\u0103 limfoganglionar\u0103 \u015fi splenic\u0103. \u00cen dou\u0103 cazuri a fost identificat\u0103 necroz\u0103 tubular\u0103 renal\u0103 acut\u0103.
\nCu exceptia cazului cu trombembolie pulmonar\u0103, tanatogeneza a inclus at\u00e2t afectarea pulmonar\u0103 (afectare alveolar\u0103 difuz\u0103, microinfarcte pulmonare) c\u00e2t \u0219i cea miocardic\u0103 (miocardita intersti\u021bial\u0103 eventual cu leziuni cardiomiocitare distrofice).
\nRezultatele noastre sunt similare altor raport\u0103ri \u00een ceea ce prive\u0219te tipul de leziuni pulmonare, prezen\u021ba macro \u0219i microtrombozelor \u0219i a fenomenelor tromboembolice pulmonare, leziunile cardiace \u0219i renale \u0219i adaug\u0103 noi leziuni \u00een ceea ce prive\u0219te distrofiile miocardice, afectarea hepatic\u0103, splenic\u0103 \u0219i suprarenalian\u0103.<\/p>\n
Scurt CV<\/span><\/p>\nProfessor of Pathology in Faculty of Dental Medicine, University of Medicine and Pharmacy \u201cCarol Davila\u201d Bucharest, senior pathologist and head of the Department of Pathologicy Colentina University Hospital, Bucharest, Romania.
\nSpecializations in the field of dermatopathology (Austria 2012), molecular biology (Italy 2012), digestive pathology (Bucharest 2016, 2015, 2011, 2010, 2009 and 2008), oral pathology (the Netherlands 2005-2006), immunohistochemistry (Bucharest 2004; Greece 2001 ), lymphoid pathology (Greece 2001), pulmonary pathology (Italy 1999), soft tissue pathology (Greece 1997), liver pathology (Greece 1996)
\nMember of the European Society of Pathology, International Academy of Pathology, International Society of Dermatopathology, Romanian Society of Dermatooncology, Romanian Association of Immunodermatology, European Academy of Dermatovenerology
\nAuthor of over 330 scientific papers presented at national and international congresses and symposiums, over 125 articles published in specialized magazines, 23 specialized chapters \/ monographs. H-index (WOS all data bases) 10; citations: 460.
\nResearcher \/ manager \/ project manager in 16 research projects
\nAreas of interest: dermatopathology, oral pathology, infectious pathology, soft tissue tumors<\/p>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22″ background_color=”rgba(117,194,33,0.23)” background_image=”https:\/\/pdi.ro\/2020\/wp-content\/uploads\/2020\/02\/back_justflowers_overlay1.png” background_blend=”luminosity” custom_padding=”54px|0px|0|0px|false|false” top_divider_style=”waves2″ top_divider_color=”#ffffff” top_divider_height=”155px” top_divider_height_tablet=”” top_divider_height_phone=”97px” top_divider_height_last_edited=”on|desktop” bottom_divider_style=”waves2″ bottom_divider_color=”#75c221″ bottom_divider_flip=”vertical” bottom_divider_height_tablet=”” bottom_divider_height_phone=”59px” bottom_divider_height_last_edited=”on|desktop”][et_pb_row column_structure=”3_5,2_5″ _builder_version=”3.25″ custom_padding=”61px|0px|69px|0px|false|false”][et_pb_column type=”3_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.0.11″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” text_line_height=”1.2em” header_font=”||||||||” background_layout=”dark” text_font_size_tablet=”” text_font_size_phone=”” text_font_size_last_edited=”on|desktop”]<\/p>\n
Contacteaz\u0103 operatorul PDI 2020<\/p>\n
[\/et_pb_text][et_pb_contact_form email=”contact@primaderma.ro\/2019″ submit_button_text=”Trimite mesajul” _builder_version=”3.19.4″ title_font=”||||||||”][et_pb_contact_field field_id=”Name” field_title=”Nume” _builder_version=”3.18.9″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Email” field_title=”Adresa de e-mail” field_type=”email” _builder_version=”3.19.4″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Message” field_title=”Mesajul dvs.” field_type=”text” fullwidth_field=”on” _builder_version=”3.18.9″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][\/et_pb_contact_form][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.0.11″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark”]<\/p>\n
Operatorul PDI 2020<\/p>\n
[\/et_pb_text][et_pb_text _builder_version=”4.0.11″ text_font=”||||||||”]<\/p>\n
![\"\"](\"https:\/\/pdi.ro\/2020\/wp-content\/uploads\/2020\/02\/eventer_logo_150px.png\")
<\/span><\/p>\n<\/span><\/p>\n<\/span><\/p>\nAdresa: Str. A. Panu nr. 13, Iasi<\/span>
Tel.: 0332.40.88.00-05<\/span>
E-mail: inscrieri@primaderma.ro<\/a>
<\/span>Website:\u00a0<\/span>www.eventernet.ro<\/a><\/p>\n[\/et_pb_text][et_pb_text disabled_on=”off|off|off” _builder_version=”4.0.11″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” locked=”off”]<\/p>\n
Parteneri Media<\/p>\n
[\/et_pb_text][et_pb_gallery gallery_ids=”7203,7204,7232,7231″ fullwidth=”on” _builder_version=”4.0.11″ transform_scale=”86%|86%” max_width=”63%” auto=”on” auto_speed=”3500″ hover_transition_duration=”100ms” hover_transition_delay=”50ms” hover_transition_speed_curve=”ease-in-out” locked=”off”][\/et_pb_gallery][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"
Prof. Dr. Zurac Sabina Universitatea de Medicin\u0103 \u015fi Farmacie \u201cCarol Davila\u201d Bucure\u015fti Spitalului Clinic Colentina, Bucure\u0219ti Aspecte lezionale identificate necroptic \u00een COVID-19. Experien\u0163a Spitalului Clinic Colentina Autori: Sabina Zurac, Luciana Nichita, Cristiana Popp, Mirela Cioplea, Alexandra Bastian, Lelia Iliescu, Ioana Simion Apari\u021bia unui nou patogen ridic\u0103 \u00eentotdeauna \u00eentreb\u0103ri asupra modalit\u0103\u021bilor prin care acesta determin\u0103 leziuni […]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-8671","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/pages\/8671","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/comments?post=8671"}],"version-history":[{"count":4,"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/pages\/8671\/revisions"}],"predecessor-version":[{"id":8676,"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/pages\/8671\/revisions\/8676"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/media?parent=8671"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
<\/strong><\/span><\/h5>\n<\/strong><\/span><\/h5>\nProf. Dr. Zurac Sabina<\/strong><\/span>
\nUniversitatea de Medicin\u0103 \u015fi Farmacie \u201cCarol Davila\u201d Bucure\u015fti
\n Spitalului Clinic Colentina, Bucure\u0219ti
\n<\/strong><\/span><\/h5>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”3.25″ locked=”off”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ hover_enabled=”0″]<\/p>\n
Aspecte lezionale identificate necroptic \u00een COVID-19. Experien\u0163a Spitalului Clinic Colentina<\/span>
\n Autori: Sabina Zurac, Luciana Nichita, Cristiana Popp, Mirela Cioplea, Alexandra Bastian, Lelia Iliescu, Ioana Simion<\/span><\/p>\nApari\u021bia unui nou patogen ridic\u0103 \u00eentotdeauna \u00eentreb\u0103ri asupra modalit\u0103\u021bilor prin care acesta determin\u0103 leziuni \u00een organismul uman, r\u0103spunsul evident fiind efectuarea de autopsii la persoanele care decedeaz\u0103 de aceast\u0103 boal\u0103. Necesitatea identific\u0103rii substratului morfopatologic al leziunilor \u00een COVID-19 este evident\u0103 dar trebuie evaluate cu aten\u021bie condi\u021biile \u00een care se efectueaz\u0103 autopsiile, fiind necesare s\u0103li de autopsie cu circuite func\u021bionale care s\u0103 asigure protec\u021bia personalului care efectueaz\u0103 autopsia \u0219i care s\u0103 previn r\u0103sp\u00e2ndirea accidental\u0103 a virusului. Av\u00e2nd \u00een vedere aceste considerente, precum \u0219i prevederile legale \u00een vigoare (evaluarea atent\u0103 a fiec\u0103rui caz de deces cu infec\u021bie SARS-Cov2 \u0219i posibilitatea de efectuare de autopsii \u00een scop \u0219tiin\u021bific pe baza unui proiect de cercetare aprobat de Comisia de Etic\u0103 a institu\u021biei), \u00een Spitalul Clinic Colentina am efectuat \u00een decurs de o lun\u0103 4 autopsii la deceda\u021bi cu COVID-19.
\nAntecedentele personale patologice ale deceda\u021bilor identific\u0103 \u00eentre comorbidit\u0103\u021bi cel mai frecvent hipertensiunea arterial\u0103, fibrila\u021bia atrial\u0103 \u0219i diabetul zaharat de tip 2. Trei pacien\u021bi erau supraponderali f\u0103r\u0103 s\u0103 fie obezi. O pacient\u0103 asocia concomitent \u0219i infec\u021bie cu virus gripal B.
\nTabloul lezional al deceda\u021bilor cu COVID 19 autopsia\u021bi a fost relativ similar, predomin\u00e2nd leziunile vasculare de ordin trombotic cu apari\u021bia fie a trombemboliei pulmonare \u00eentr-un caz, fie a infarctelor pulmonare (\u00een toate cazurile), splenice (2 cazuri) sau suprarenaliene (2 cazuri) \u0219i leziunile miocardice (miocardit\u0103 intersti\u021bial\u0103 \u00een toate cazurile \u0219i leziuni distrofice miocardice \u00een 2 cazuri). Trei deceda\u021bi au prezentat afectare alveolar\u0103 difuz\u0103 (substratul morfologic al sindromului de detres\u0103 respiratorie a adultului) grad I (un caz) \u0219i grad I-II (2 cazuri) iar \u00een dou\u0103 cazuri au fost identificate \u015fi mici focare diseminate, bilaterale, de bronhopneumonie. To\u021bi pacien\u021bii au prezentat miocardoscleroz\u0103 ca leziuni miocardice preexistente. Toate cazurile au prezentat steatoz\u0103 hepatic\u0103 (macro\/medio\/microvacuolar\u0103 2 cazuri, macrovacuolar\u0103 un caz, microvacuolar\u0103 un caz) \u0219i deple\u0163ie limfoid\u0103 limfoganglionar\u0103 \u015fi splenic\u0103. \u00cen dou\u0103 cazuri a fost identificat\u0103 necroz\u0103 tubular\u0103 renal\u0103 acut\u0103.
\nCu exceptia cazului cu trombembolie pulmonar\u0103, tanatogeneza a inclus at\u00e2t afectarea pulmonar\u0103 (afectare alveolar\u0103 difuz\u0103, microinfarcte pulmonare) c\u00e2t \u0219i cea miocardic\u0103 (miocardita intersti\u021bial\u0103 eventual cu leziuni cardiomiocitare distrofice).
\nRezultatele noastre sunt similare altor raport\u0103ri \u00een ceea ce prive\u0219te tipul de leziuni pulmonare, prezen\u021ba macro \u0219i microtrombozelor \u0219i a fenomenelor tromboembolice pulmonare, leziunile cardiace \u0219i renale \u0219i adaug\u0103 noi leziuni \u00een ceea ce prive\u0219te distrofiile miocardice, afectarea hepatic\u0103, splenic\u0103 \u0219i suprarenalian\u0103.<\/p>\n
Scurt CV<\/span><\/p>\nProfessor of Pathology in Faculty of Dental Medicine, University of Medicine and Pharmacy \u201cCarol Davila\u201d Bucharest, senior pathologist and head of the Department of Pathologicy Colentina University Hospital, Bucharest, Romania.
\nSpecializations in the field of dermatopathology (Austria 2012), molecular biology (Italy 2012), digestive pathology (Bucharest 2016, 2015, 2011, 2010, 2009 and 2008), oral pathology (the Netherlands 2005-2006), immunohistochemistry (Bucharest 2004; Greece 2001 ), lymphoid pathology (Greece 2001), pulmonary pathology (Italy 1999), soft tissue pathology (Greece 1997), liver pathology (Greece 1996)
\nMember of the European Society of Pathology, International Academy of Pathology, International Society of Dermatopathology, Romanian Society of Dermatooncology, Romanian Association of Immunodermatology, European Academy of Dermatovenerology
\nAuthor of over 330 scientific papers presented at national and international congresses and symposiums, over 125 articles published in specialized magazines, 23 specialized chapters \/ monographs. H-index (WOS all data bases) 10; citations: 460.
\nResearcher \/ manager \/ project manager in 16 research projects
\nAreas of interest: dermatopathology, oral pathology, infectious pathology, soft tissue tumors<\/p>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22″ background_color=”rgba(117,194,33,0.23)” background_image=”https:\/\/pdi.ro\/2020\/wp-content\/uploads\/2020\/02\/back_justflowers_overlay1.png” background_blend=”luminosity” custom_padding=”54px|0px|0|0px|false|false” top_divider_style=”waves2″ top_divider_color=”#ffffff” top_divider_height=”155px” top_divider_height_tablet=”” top_divider_height_phone=”97px” top_divider_height_last_edited=”on|desktop” bottom_divider_style=”waves2″ bottom_divider_color=”#75c221″ bottom_divider_flip=”vertical” bottom_divider_height_tablet=”” bottom_divider_height_phone=”59px” bottom_divider_height_last_edited=”on|desktop”][et_pb_row column_structure=”3_5,2_5″ _builder_version=”3.25″ custom_padding=”61px|0px|69px|0px|false|false”][et_pb_column type=”3_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.0.11″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” text_line_height=”1.2em” header_font=”||||||||” background_layout=”dark” text_font_size_tablet=”” text_font_size_phone=”” text_font_size_last_edited=”on|desktop”]<\/p>\n
Contacteaz\u0103 operatorul PDI 2020<\/p>\n
[\/et_pb_text][et_pb_contact_form email=”contact@primaderma.ro\/2019″ submit_button_text=”Trimite mesajul” _builder_version=”3.19.4″ title_font=”||||||||”][et_pb_contact_field field_id=”Name” field_title=”Nume” _builder_version=”3.18.9″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Email” field_title=”Adresa de e-mail” field_type=”email” _builder_version=”3.19.4″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Message” field_title=”Mesajul dvs.” field_type=”text” fullwidth_field=”on” _builder_version=”3.18.9″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][\/et_pb_contact_form][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.0.11″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark”]<\/p>\n
Operatorul PDI 2020<\/p>\n
[\/et_pb_text][et_pb_text _builder_version=”4.0.11″ text_font=”||||||||”]<\/p>\n
<\/span><\/p>\n<\/span><\/p>\n<\/span><\/p>\nAdresa: Str. A. Panu nr. 13, Iasi<\/span>
Tel.: 0332.40.88.00-05<\/span>
E-mail: inscrieri@primaderma.ro<\/a>
<\/span>Website:\u00a0<\/span>www.eventernet.ro<\/a><\/p>\n[\/et_pb_text][et_pb_text disabled_on=”off|off|off” _builder_version=”4.0.11″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” locked=”off”]<\/p>\n
Parteneri Media<\/p>\n
[\/et_pb_text][et_pb_gallery gallery_ids=”7203,7204,7232,7231″ fullwidth=”on” _builder_version=”4.0.11″ transform_scale=”86%|86%” max_width=”63%” auto=”on” auto_speed=”3500″ hover_transition_duration=”100ms” hover_transition_delay=”50ms” hover_transition_speed_curve=”ease-in-out” locked=”off”][\/et_pb_gallery][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"
Prof. Dr. Zurac Sabina Universitatea de Medicin\u0103 \u015fi Farmacie \u201cCarol Davila\u201d Bucure\u015fti Spitalului Clinic Colentina, Bucure\u0219ti Aspecte lezionale identificate necroptic \u00een COVID-19. Experien\u0163a Spitalului Clinic Colentina Autori: Sabina Zurac, Luciana Nichita, Cristiana Popp, Mirela Cioplea, Alexandra Bastian, Lelia Iliescu, Ioana Simion Apari\u021bia unui nou patogen ridic\u0103 \u00eentotdeauna \u00eentreb\u0103ri asupra modalit\u0103\u021bilor prin care acesta determin\u0103 leziuni […]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-8671","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/pages\/8671","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/comments?post=8671"}],"version-history":[{"count":4,"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/pages\/8671\/revisions"}],"predecessor-version":[{"id":8676,"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/pages\/8671\/revisions\/8676"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/media?parent=8671"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Prof. Dr. Zurac Sabina<\/strong><\/span>
\nUniversitatea de Medicin\u0103 \u015fi Farmacie \u201cCarol Davila\u201d Bucure\u015fti
\n Spitalului Clinic Colentina, Bucure\u0219ti
\n<\/strong><\/span><\/h5>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”3.25″ locked=”off”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ hover_enabled=”0″]<\/p>\n
Aspecte lezionale identificate necroptic \u00een COVID-19. Experien\u0163a Spitalului Clinic Colentina<\/span>
\n Autori: Sabina Zurac, Luciana Nichita, Cristiana Popp, Mirela Cioplea, Alexandra Bastian, Lelia Iliescu, Ioana Simion<\/span><\/p>\nApari\u021bia unui nou patogen ridic\u0103 \u00eentotdeauna \u00eentreb\u0103ri asupra modalit\u0103\u021bilor prin care acesta determin\u0103 leziuni \u00een organismul uman, r\u0103spunsul evident fiind efectuarea de autopsii la persoanele care decedeaz\u0103 de aceast\u0103 boal\u0103. Necesitatea identific\u0103rii substratului morfopatologic al leziunilor \u00een COVID-19 este evident\u0103 dar trebuie evaluate cu aten\u021bie condi\u021biile \u00een care se efectueaz\u0103 autopsiile, fiind necesare s\u0103li de autopsie cu circuite func\u021bionale care s\u0103 asigure protec\u021bia personalului care efectueaz\u0103 autopsia \u0219i care s\u0103 previn r\u0103sp\u00e2ndirea accidental\u0103 a virusului. Av\u00e2nd \u00een vedere aceste considerente, precum \u0219i prevederile legale \u00een vigoare (evaluarea atent\u0103 a fiec\u0103rui caz de deces cu infec\u021bie SARS-Cov2 \u0219i posibilitatea de efectuare de autopsii \u00een scop \u0219tiin\u021bific pe baza unui proiect de cercetare aprobat de Comisia de Etic\u0103 a institu\u021biei), \u00een Spitalul Clinic Colentina am efectuat \u00een decurs de o lun\u0103 4 autopsii la deceda\u021bi cu COVID-19.
\nAntecedentele personale patologice ale deceda\u021bilor identific\u0103 \u00eentre comorbidit\u0103\u021bi cel mai frecvent hipertensiunea arterial\u0103, fibrila\u021bia atrial\u0103 \u0219i diabetul zaharat de tip 2. Trei pacien\u021bi erau supraponderali f\u0103r\u0103 s\u0103 fie obezi. O pacient\u0103 asocia concomitent \u0219i infec\u021bie cu virus gripal B.
\nTabloul lezional al deceda\u021bilor cu COVID 19 autopsia\u021bi a fost relativ similar, predomin\u00e2nd leziunile vasculare de ordin trombotic cu apari\u021bia fie a trombemboliei pulmonare \u00eentr-un caz, fie a infarctelor pulmonare (\u00een toate cazurile), splenice (2 cazuri) sau suprarenaliene (2 cazuri) \u0219i leziunile miocardice (miocardit\u0103 intersti\u021bial\u0103 \u00een toate cazurile \u0219i leziuni distrofice miocardice \u00een 2 cazuri). Trei deceda\u021bi au prezentat afectare alveolar\u0103 difuz\u0103 (substratul morfologic al sindromului de detres\u0103 respiratorie a adultului) grad I (un caz) \u0219i grad I-II (2 cazuri) iar \u00een dou\u0103 cazuri au fost identificate \u015fi mici focare diseminate, bilaterale, de bronhopneumonie. To\u021bi pacien\u021bii au prezentat miocardoscleroz\u0103 ca leziuni miocardice preexistente. Toate cazurile au prezentat steatoz\u0103 hepatic\u0103 (macro\/medio\/microvacuolar\u0103 2 cazuri, macrovacuolar\u0103 un caz, microvacuolar\u0103 un caz) \u0219i deple\u0163ie limfoid\u0103 limfoganglionar\u0103 \u015fi splenic\u0103. \u00cen dou\u0103 cazuri a fost identificat\u0103 necroz\u0103 tubular\u0103 renal\u0103 acut\u0103.
\nCu exceptia cazului cu trombembolie pulmonar\u0103, tanatogeneza a inclus at\u00e2t afectarea pulmonar\u0103 (afectare alveolar\u0103 difuz\u0103, microinfarcte pulmonare) c\u00e2t \u0219i cea miocardic\u0103 (miocardita intersti\u021bial\u0103 eventual cu leziuni cardiomiocitare distrofice).
\nRezultatele noastre sunt similare altor raport\u0103ri \u00een ceea ce prive\u0219te tipul de leziuni pulmonare, prezen\u021ba macro \u0219i microtrombozelor \u0219i a fenomenelor tromboembolice pulmonare, leziunile cardiace \u0219i renale \u0219i adaug\u0103 noi leziuni \u00een ceea ce prive\u0219te distrofiile miocardice, afectarea hepatic\u0103, splenic\u0103 \u0219i suprarenalian\u0103.<\/p>\n
Scurt CV<\/span><\/p>\nProfessor of Pathology in Faculty of Dental Medicine, University of Medicine and Pharmacy \u201cCarol Davila\u201d Bucharest, senior pathologist and head of the Department of Pathologicy Colentina University Hospital, Bucharest, Romania.
\nSpecializations in the field of dermatopathology (Austria 2012), molecular biology (Italy 2012), digestive pathology (Bucharest 2016, 2015, 2011, 2010, 2009 and 2008), oral pathology (the Netherlands 2005-2006), immunohistochemistry (Bucharest 2004; Greece 2001 ), lymphoid pathology (Greece 2001), pulmonary pathology (Italy 1999), soft tissue pathology (Greece 1997), liver pathology (Greece 1996)
\nMember of the European Society of Pathology, International Academy of Pathology, International Society of Dermatopathology, Romanian Society of Dermatooncology, Romanian Association of Immunodermatology, European Academy of Dermatovenerology
\nAuthor of over 330 scientific papers presented at national and international congresses and symposiums, over 125 articles published in specialized magazines, 23 specialized chapters \/ monographs. H-index (WOS all data bases) 10; citations: 460.
\nResearcher \/ manager \/ project manager in 16 research projects
\nAreas of interest: dermatopathology, oral pathology, infectious pathology, soft tissue tumors<\/p>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22″ background_color=”rgba(117,194,33,0.23)” background_image=”https:\/\/pdi.ro\/2020\/wp-content\/uploads\/2020\/02\/back_justflowers_overlay1.png” background_blend=”luminosity” custom_padding=”54px|0px|0|0px|false|false” top_divider_style=”waves2″ top_divider_color=”#ffffff” top_divider_height=”155px” top_divider_height_tablet=”” top_divider_height_phone=”97px” top_divider_height_last_edited=”on|desktop” bottom_divider_style=”waves2″ bottom_divider_color=”#75c221″ bottom_divider_flip=”vertical” bottom_divider_height_tablet=”” bottom_divider_height_phone=”59px” bottom_divider_height_last_edited=”on|desktop”][et_pb_row column_structure=”3_5,2_5″ _builder_version=”3.25″ custom_padding=”61px|0px|69px|0px|false|false”][et_pb_column type=”3_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.0.11″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” text_line_height=”1.2em” header_font=”||||||||” background_layout=”dark” text_font_size_tablet=”” text_font_size_phone=”” text_font_size_last_edited=”on|desktop”]<\/p>\n
Contacteaz\u0103 operatorul PDI 2020<\/p>\n
[\/et_pb_text][et_pb_contact_form email=”contact@primaderma.ro\/2019″ submit_button_text=”Trimite mesajul” _builder_version=”3.19.4″ title_font=”||||||||”][et_pb_contact_field field_id=”Name” field_title=”Nume” _builder_version=”3.18.9″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Email” field_title=”Adresa de e-mail” field_type=”email” _builder_version=”3.19.4″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Message” field_title=”Mesajul dvs.” field_type=”text” fullwidth_field=”on” _builder_version=”3.18.9″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][\/et_pb_contact_form][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.0.11″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark”]<\/p>\n
Operatorul PDI 2020<\/p>\n
[\/et_pb_text][et_pb_text _builder_version=”4.0.11″ text_font=”||||||||”]<\/p>\n
<\/span><\/p>\n<\/span><\/p>\n<\/span><\/p>\nAdresa: Str. A. Panu nr. 13, Iasi<\/span>
Tel.: 0332.40.88.00-05<\/span>
E-mail: inscrieri@primaderma.ro<\/a>
<\/span>Website:\u00a0<\/span>www.eventernet.ro<\/a><\/p>\n[\/et_pb_text][et_pb_text disabled_on=”off|off|off” _builder_version=”4.0.11″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” locked=”off”]<\/p>\n
Parteneri Media<\/p>\n
[\/et_pb_text][et_pb_gallery gallery_ids=”7203,7204,7232,7231″ fullwidth=”on” _builder_version=”4.0.11″ transform_scale=”86%|86%” max_width=”63%” auto=”on” auto_speed=”3500″ hover_transition_duration=”100ms” hover_transition_delay=”50ms” hover_transition_speed_curve=”ease-in-out” locked=”off”][\/et_pb_gallery][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"
Prof. Dr. Zurac Sabina Universitatea de Medicin\u0103 \u015fi Farmacie \u201cCarol Davila\u201d Bucure\u015fti Spitalului Clinic Colentina, Bucure\u0219ti Aspecte lezionale identificate necroptic \u00een COVID-19. Experien\u0163a Spitalului Clinic Colentina Autori: Sabina Zurac, Luciana Nichita, Cristiana Popp, Mirela Cioplea, Alexandra Bastian, Lelia Iliescu, Ioana Simion Apari\u021bia unui nou patogen ridic\u0103 \u00eentotdeauna \u00eentreb\u0103ri asupra modalit\u0103\u021bilor prin care acesta determin\u0103 leziuni […]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-8671","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/pages\/8671","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/comments?post=8671"}],"version-history":[{"count":4,"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/pages\/8671\/revisions"}],"predecessor-version":[{"id":8676,"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/pages\/8671\/revisions\/8676"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/media?parent=8671"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\n Autori: Sabina Zurac, Luciana Nichita, Cristiana Popp, Mirela Cioplea, Alexandra Bastian, Lelia Iliescu, Ioana Simion<\/span><\/p>\n
Apari\u021bia unui nou patogen ridic\u0103 \u00eentotdeauna \u00eentreb\u0103ri asupra modalit\u0103\u021bilor prin care acesta determin\u0103 leziuni \u00een organismul uman, r\u0103spunsul evident fiind efectuarea de autopsii la persoanele care decedeaz\u0103 de aceast\u0103 boal\u0103. Necesitatea identific\u0103rii substratului morfopatologic al leziunilor \u00een COVID-19 este evident\u0103 dar trebuie evaluate cu aten\u021bie condi\u021biile \u00een care se efectueaz\u0103 autopsiile, fiind necesare s\u0103li de autopsie cu circuite func\u021bionale care s\u0103 asigure protec\u021bia personalului care efectueaz\u0103 autopsia \u0219i care s\u0103 previn r\u0103sp\u00e2ndirea accidental\u0103 a virusului. Av\u00e2nd \u00een vedere aceste considerente, precum \u0219i prevederile legale \u00een vigoare (evaluarea atent\u0103 a fiec\u0103rui caz de deces cu infec\u021bie SARS-Cov2 \u0219i posibilitatea de efectuare de autopsii \u00een scop \u0219tiin\u021bific pe baza unui proiect de cercetare aprobat de Comisia de Etic\u0103 a institu\u021biei), \u00een Spitalul Clinic Colentina am efectuat \u00een decurs de o lun\u0103 4 autopsii la deceda\u021bi cu COVID-19.
\nAntecedentele personale patologice ale deceda\u021bilor identific\u0103 \u00eentre comorbidit\u0103\u021bi cel mai frecvent hipertensiunea arterial\u0103, fibrila\u021bia atrial\u0103 \u0219i diabetul zaharat de tip 2. Trei pacien\u021bi erau supraponderali f\u0103r\u0103 s\u0103 fie obezi. O pacient\u0103 asocia concomitent \u0219i infec\u021bie cu virus gripal B.
\nTabloul lezional al deceda\u021bilor cu COVID 19 autopsia\u021bi a fost relativ similar, predomin\u00e2nd leziunile vasculare de ordin trombotic cu apari\u021bia fie a trombemboliei pulmonare \u00eentr-un caz, fie a infarctelor pulmonare (\u00een toate cazurile), splenice (2 cazuri) sau suprarenaliene (2 cazuri) \u0219i leziunile miocardice (miocardit\u0103 intersti\u021bial\u0103 \u00een toate cazurile \u0219i leziuni distrofice miocardice \u00een 2 cazuri). Trei deceda\u021bi au prezentat afectare alveolar\u0103 difuz\u0103 (substratul morfologic al sindromului de detres\u0103 respiratorie a adultului) grad I (un caz) \u0219i grad I-II (2 cazuri) iar \u00een dou\u0103 cazuri au fost identificate \u015fi mici focare diseminate, bilaterale, de bronhopneumonie. To\u021bi pacien\u021bii au prezentat miocardoscleroz\u0103 ca leziuni miocardice preexistente. Toate cazurile au prezentat steatoz\u0103 hepatic\u0103 (macro\/medio\/microvacuolar\u0103 2 cazuri, macrovacuolar\u0103 un caz, microvacuolar\u0103 un caz) \u0219i deple\u0163ie limfoid\u0103 limfoganglionar\u0103 \u015fi splenic\u0103. \u00cen dou\u0103 cazuri a fost identificat\u0103 necroz\u0103 tubular\u0103 renal\u0103 acut\u0103.
\nCu exceptia cazului cu trombembolie pulmonar\u0103, tanatogeneza a inclus at\u00e2t afectarea pulmonar\u0103 (afectare alveolar\u0103 difuz\u0103, microinfarcte pulmonare) c\u00e2t \u0219i cea miocardic\u0103 (miocardita intersti\u021bial\u0103 eventual cu leziuni cardiomiocitare distrofice).
\nRezultatele noastre sunt similare altor raport\u0103ri \u00een ceea ce prive\u0219te tipul de leziuni pulmonare, prezen\u021ba macro \u0219i microtrombozelor \u0219i a fenomenelor tromboembolice pulmonare, leziunile cardiace \u0219i renale \u0219i adaug\u0103 noi leziuni \u00een ceea ce prive\u0219te distrofiile miocardice, afectarea hepatic\u0103, splenic\u0103 \u0219i suprarenalian\u0103.<\/p>\n
Scurt CV<\/span><\/p>\n Professor of Pathology in Faculty of Dental Medicine, University of Medicine and Pharmacy \u201cCarol Davila\u201d Bucharest, senior pathologist and head of the Department of Pathologicy Colentina University Hospital, Bucharest, Romania. [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22″ background_color=”rgba(117,194,33,0.23)” background_image=”https:\/\/pdi.ro\/2020\/wp-content\/uploads\/2020\/02\/back_justflowers_overlay1.png” background_blend=”luminosity” custom_padding=”54px|0px|0|0px|false|false” top_divider_style=”waves2″ top_divider_color=”#ffffff” top_divider_height=”155px” top_divider_height_tablet=”” top_divider_height_phone=”97px” top_divider_height_last_edited=”on|desktop” bottom_divider_style=”waves2″ bottom_divider_color=”#75c221″ bottom_divider_flip=”vertical” bottom_divider_height_tablet=”” bottom_divider_height_phone=”59px” bottom_divider_height_last_edited=”on|desktop”][et_pb_row column_structure=”3_5,2_5″ _builder_version=”3.25″ custom_padding=”61px|0px|69px|0px|false|false”][et_pb_column type=”3_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.0.11″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” text_line_height=”1.2em” header_font=”||||||||” background_layout=”dark” text_font_size_tablet=”” text_font_size_phone=”” text_font_size_last_edited=”on|desktop”]<\/p>\n Contacteaz\u0103 operatorul PDI 2020<\/p>\n [\/et_pb_text][et_pb_contact_form email=”contact@primaderma.ro\/2019″ submit_button_text=”Trimite mesajul” _builder_version=”3.19.4″ title_font=”||||||||”][et_pb_contact_field field_id=”Name” field_title=”Nume” _builder_version=”3.18.9″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Email” field_title=”Adresa de e-mail” field_type=”email” _builder_version=”3.19.4″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Message” field_title=”Mesajul dvs.” field_type=”text” fullwidth_field=”on” _builder_version=”3.18.9″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][\/et_pb_contact_form][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.0.11″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark”]<\/p>\n Operatorul PDI 2020<\/p>\n [\/et_pb_text][et_pb_text _builder_version=”4.0.11″ text_font=”||||||||”]<\/p>\n <\/span><\/p>\n <\/span><\/p>\n Adresa: Str. A. Panu nr. 13, Iasi<\/span> [\/et_pb_text][et_pb_text disabled_on=”off|off|off” _builder_version=”4.0.11″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” locked=”off”]<\/p>\n Parteneri Media<\/p>\n [\/et_pb_text][et_pb_gallery gallery_ids=”7203,7204,7232,7231″ fullwidth=”on” _builder_version=”4.0.11″ transform_scale=”86%|86%” max_width=”63%” auto=”on” auto_speed=”3500″ hover_transition_duration=”100ms” hover_transition_delay=”50ms” hover_transition_speed_curve=”ease-in-out” locked=”off”][\/et_pb_gallery][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" Prof. Dr. Zurac Sabina Universitatea de Medicin\u0103 \u015fi Farmacie \u201cCarol Davila\u201d Bucure\u015fti Spitalului Clinic Colentina, Bucure\u0219ti Aspecte lezionale identificate necroptic \u00een COVID-19. Experien\u0163a Spitalului Clinic Colentina Autori: Sabina Zurac, Luciana Nichita, Cristiana Popp, Mirela Cioplea, Alexandra Bastian, Lelia Iliescu, Ioana Simion Apari\u021bia unui nou patogen ridic\u0103 \u00eentotdeauna \u00eentreb\u0103ri asupra modalit\u0103\u021bilor prin care acesta determin\u0103 leziuni […]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-8671","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/pages\/8671","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/comments?post=8671"}],"version-history":[{"count":4,"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/pages\/8671\/revisions"}],"predecessor-version":[{"id":8676,"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/pages\/8671\/revisions\/8676"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2020\/wp-json\/wp\/v2\/media?parent=8671"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\nSpecializations in the field of dermatopathology (Austria 2012), molecular biology (Italy 2012), digestive pathology (Bucharest 2016, 2015, 2011, 2010, 2009 and 2008), oral pathology (the Netherlands 2005-2006), immunohistochemistry (Bucharest 2004; Greece 2001 ), lymphoid pathology (Greece 2001), pulmonary pathology (Italy 1999), soft tissue pathology (Greece 1997), liver pathology (Greece 1996)
\nMember of the European Society of Pathology, International Academy of Pathology, International Society of Dermatopathology, Romanian Society of Dermatooncology, Romanian Association of Immunodermatology, European Academy of Dermatovenerology
\nAuthor of over 330 scientific papers presented at national and international congresses and symposiums, over 125 articles published in specialized magazines, 23 specialized chapters \/ monographs. H-index (WOS all data bases) 10; citations: 460.
\nResearcher \/ manager \/ project manager in 16 research projects
\nAreas of interest: dermatopathology, oral pathology, infectious pathology, soft tissue tumors<\/p>\n<\/span><\/p>\n
Tel.: 0332.40.88.00-05<\/span>
E-mail: inscrieri@primaderma.ro<\/a>
<\/span>Website:\u00a0<\/span>www.eventernet.ro<\/a><\/p>\n