{"id":10100,"date":"2021-07-07T14:12:08","date_gmt":"2021-07-07T12:12:08","guid":{"rendered":"https:\/\/primaderma.ro\/?page_id=10100"},"modified":"2021-07-07T14:12:08","modified_gmt":"2021-07-07T12:12:08","slug":"prof-dr-tuta-liliana-lili","status":"publish","type":"page","link":"https:\/\/pdi.ro\/2021\/prof-dr-tuta-liliana-lili\/","title":{"rendered":"Prof. Dr.\u00a0Tu\u021b\u0103 Liliana Lili"},"content":{"rendered":"

[et_pb_section fb_built=”1″ fullwidth=”on” disabled_on=”on|off|off” _builder_version=”3.22″ custom_margin=”||” custom_padding=”15px||29px” top_divider_style=”waves2″ top_divider_color=”#f0622a” top_divider_flip=”horizontal|vertical” bottom_divider_style=”waves2″ bottom_divider_color=”#fcdedb” bottom_divider_height=”105px” bottom_divider_flip=”vertical” global_module=”9062″ collapsed=”off”][et_pb_fullwidth_header title=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF90aXRsZSIsInNldHRpbmdzIjp7ImJlZm9yZSI6IiIsImFmdGVyIjoiIn19@” text_orientation=”right” header_image_url=”https:\/\/pdi.ro\/2021\/wp-content\/uploads\/2021\/05\/PDI2021_logo_header_int_600x300px.png” disabled_on=”on|on|off” _builder_version=”4.9.4″ _dynamic_attributes=”title” title_font=”Kaushan Script||||||||” title_text_align=”right” title_text_color=”#f0622a” title_font_size=”50px” content_font=”|600||on|||||” content_text_align=”center” content_text_color=”#686766″ content_font_size=”15px” subhead_font=”||||||||” background_color=”#ef916b” background_image=”https:\/\/pdi.ro\/2021\/wp-content\/uploads\/2021\/05\/PDI2021_header_1920x550px.jpg” background_blend=”luminosity” background_layout=”light” custom_margin=”0px||8px” custom_padding=”40px||40px||true” content_font_size_tablet=”” content_font_size_phone=”15px” content_font_size_last_edited=”on|desktop”][\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22″][et_pb_row column_structure=”2_5,3_5″ _builder_version=”3.25″][et_pb_column type=”2_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/pdi.ro\/2021\/wp-content\/uploads\/2021\/07\/Tuta_L_1.jpg” title_text=”Tuta_L_1″ align=”center” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.9.7″ max_width=”30%” hover_enabled=”0″ border_radii=”on|100px|100px|100px|100px” sticky_enabled=”0″][\/et_pb_image][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.7″ hover_enabled=”0″ sticky_enabled=”0″]<\/p>\n

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Prof. Dr.\u00a0Tu\u021b\u0103 Liliana Lili<\/span><\/strong>
\nFacultatea de Medicin\u0103, Universitatea Ovidius Constan\u021ba, Rom\u00e2nia<\/span><\/strong><\/h4>\n

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Impactul afect\u0103rii renale asupra evolu\u021biei \u0219i terapiei bolilor de \u021besut conjunctiv
Liliana-Ana Tu\u021b\u01031, Claudia Mihailov\u00b9, Emma Gheorghe2<\/span>
1Departamentul Discipline Clinice Medicale, Facultatea de Medicin\u0103, Universitatea Ovidius Constan\u021ba, Rom\u00e2nia
2Departamentul Discipline Preclinice, Facultatea de Medicin\u0103, Universitatea “Ovidius” Constan\u021ba, Rom\u00e2nia<\/p>\n

Cuvinte cheie: afectare renal\u0103, boli de \u021besut conjunctiv, punc\u021bie renal\u0103, lupus eritematos sistemic, boala mixt\u0103 de \u021besut conjunctiv<\/p>\n

Afectarea renal\u0103 este frecvent semnalat\u0103 \u00een bolile \u021besutului conjunctiv, sub forma unei mari variet\u0103\u021bi de leziuni glomerulare, tubulointerstitiale, vasculare sau mixte ale rinichiului, decelabile la punc\u021bia-biopsie renal\u0103. Cu toate acestea, informa\u021biile, chiar \u0219i cele mai recente sunt limitate cu privire la leziunile renale \u00een bolile \u021besutului conjunctiv, cu excep\u021bia lupusului eritematos sistemic (LES).
\u00cen prima parte a prezent\u0103rii vom trece \u00een revist\u0103 afectarea renal\u0103 \u00een bolile autoimune ale \u021besutului conjunctiv: lupus eritematos sistemic, artrit\u0103 reumatoid\u0103, scleroz\u0103 sistemic\u0103, sindrom Sj\u00f6gren, polimiozit\u0103\/dermatomiozit\u0103, dar \u0219i boala mixt\u0103 de \u021besut conjunctiv. Subliniem faptul c\u0103 manifest\u0103rile renale pot fi foarte variabile: de la hematurie microscopic\u0103 \u0219i\/sau proteinurie asimptomatic\u0103, p\u00e2n\u0103 la sindrom nefritic\/nefrotic sau vasculit\u0103 rapid progresiv\u0103.
Deseori, afectarea renal\u0103 este determinat\u0103 de tratamentul bolii de \u021besut conjunctiv \u0219i poate reprezenta o cauz\u0103 major\u0103 de morbiditate \u0219i mortalitate. De aceea, este important ca dermatologii, reumatologii \u0219i nefrologii s\u0103 monitorizeze \u0219i s\u0103 ajusteze terapia acestor pacien\u021bi, \u00een echip\u0103 multidisciplinar\u0103, \u0219tiind faptul c\u0103 disfunc\u021bia renal\u0103 poate apare \u00een contextul bolii autoimune primare sau este o consecin\u021b\u0103 a farmacoterapiei sale. \u00cen ambele situa\u021bii, apari\u021bia bolii cronice de rinichi impune, de multe ori, ajustarea dozelor medicamentoase \u0219i chiar \u00eengustarea spectrului terapeutic, cu impact negativ asupra prognosticului pacientului, c\u00e2t \u0219i asupra speran\u021bei \u0219i calit\u0103\u021bii vie\u021bii acestuia.<\/p>\n

Impact of kidney dysfunction in connective tissue diseases
Liliana-Ana Tu\u021b\u01031, Claudia Mihailov\u00b9, Emma Gheorghe2<\/span>
1Department of Medical Clinical Disciplines, Faculty of Medicine, Ovidius University Constan\u021ba, Romania
2Department of Preclinical Disciplines, Faculty of Medicine, Ovidius University Constan\u021ba, Romania<\/p>\n

Keywords: renal involvement, connective tissue disease, renal biopsy, systemic lupus erythematosus, mixed connective tissue disease<\/p>\n

Renal impairment is frequently reported in connective tissue diseases, in the form of a wide variety of glomerular, tubulointerstitial, vascular or mixed kidney lesions, detectable by kidney biopsy. However, even the most recent information is limited on kidney damage in connective tissue diseases, excepting systemic lupus erythematosus (SLE).
In the first part of our presentation, we will review the involvement of the kidneys in autoimmune connective tissue diseases: systemic lupus erythematosus, rheumatoid arthritis, systemic sclerosis, Sj\u00f6gren’s syndrome, polymyositis\/dermatomyositis and mixed connective tissue disease (MCTD). We emphasize that the renal manifestations can be very variable: from microscopic hematuria and\/or asymptomatic proteinuria, to nephritic\/nephrotic syndrome or rapidly progressive vasculitis.
Frequently, kidney damage is caused by the treatment of connective tissue disease itself and can be a major cause of morbidity and mortality. Therefore, it is important that dermatologists, rheumatologists and nephrologists monitor and adjust the therapy of these patients in a multidisciplinary team, knowing that renal dysfunction may occur in the context of primary autoimmune disease or is a consequence of its pharmacotherapy. In both cases, the onset of chronic kidney disease often requires adjustment of drug doses and even narrowing of the therapeutic spectrum, with a negative impact on the patient’s prognosis, as well as on his life expectancy and quality of life.<\/p>\n

Scurt CV<\/span><\/p>\n

Prof. Univ. Dr. Habil.
Medic primar medicin\u0103 intern\u0103 si nefrologie
Doctor \u00een medicin\u0103
Medic-\u0219ef Sec\u021bie Clinic\u0103 Nefrologie Spital Clinic Jude\u021bean de Urgen\u021b\u0103 Constan\u021ba
Pre\u0219edintele Comisiei de Nefrologie a Ministerului S\u0103n\u0103t\u0103\u021bii (2019- prezent)<\/p>\n

Afiliere profesional\u0103:<\/strong>
Societatea Rom\u00e2n\u0103 de Nefrologie (SRN)- Pre\u0219edinte SRN (2017-2019)
Societatea Rom\u00e2n\u0103 de Medicin\u0103 Intern\u0103 (SRMI)
Asocia\u021bia European\u0103 de Nefrologie, Dializ\u0103 \u0219i Transplant renal (ERA-ADTA)
Societatea Interna\u021bional\u0103 de Nefrologie (ISN)
Societatea American\u0103 de Nefrologie (ASN)<\/p>\n

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Contacteaz\u0103 operatorul PDI 2021<\/p>\n

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Parteneri Media<\/p>\n

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Prof. Dr.\u00a0Tu\u021b\u0103 Liliana Lili Facultatea de Medicin\u0103, Universitatea Ovidius Constan\u021ba, Rom\u00e2nia Impactul afect\u0103rii renale asupra evolu\u021biei \u0219i terapiei bolilor de \u021besut conjunctivLiliana-Ana Tu\u021b\u01031, Claudia Mihailov\u00b9, Emma Gheorghe21Departamentul Discipline Clinice Medicale, Facultatea de Medicin\u0103, Universitatea Ovidius Constan\u021ba, Rom\u00e2nia2Departamentul Discipline Preclinice, Facultatea de Medicin\u0103, Universitatea “Ovidius” Constan\u021ba, Rom\u00e2nia Cuvinte cheie: afectare renal\u0103, boli de \u021besut conjunctiv, punc\u021bie […]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-10100","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/10100","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/comments?post=10100"}],"version-history":[{"count":3,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/10100\/revisions"}],"predecessor-version":[{"id":10104,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/10100\/revisions\/10104"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/media?parent=10100"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}