{"id":10384,"date":"2021-07-12T12:08:30","date_gmt":"2021-07-12T10:08:30","guid":{"rendered":"https:\/\/primaderma.ro\/?page_id=10384"},"modified":"2021-07-15T09:44:41","modified_gmt":"2021-07-15T07:44:41","slug":"dr-brihan-ilarie","status":"publish","type":"page","link":"https:\/\/pdi.ro\/2021\/dr-brihan-ilarie\/","title":{"rendered":"Dr. Brihan Ilarie"},"content":{"rendered":"

[et_pb_section fb_built=”1″ fullwidth=”on” disabled_on=”on|off|off” _builder_version=”3.22″ custom_margin=”||” custom_padding=”15px||29px” top_divider_style=”waves2″ top_divider_color=”#f0622a” top_divider_flip=”horizontal|vertical” bottom_divider_style=”waves2″ bottom_divider_color=”#fcdedb” bottom_divider_height=”105px” bottom_divider_flip=”vertical” global_module=”9062″ collapsed=”off”][et_pb_fullwidth_header title=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF90aXRsZSIsInNldHRpbmdzIjp7ImJlZm9yZSI6IiIsImFmdGVyIjoiIn19@” text_orientation=”right” header_image_url=”https:\/\/pdi.ro\/2021\/wp-content\/uploads\/2021\/05\/PDI2021_logo_header_int_600x300px.png” disabled_on=”on|on|off” _builder_version=”4.9.4″ _dynamic_attributes=”title” title_font=”Kaushan Script||||||||” title_text_align=”right” title_text_color=”#f0622a” title_font_size=”50px” content_font=”|600||on|||||” content_text_align=”center” content_text_color=”#686766″ content_font_size=”15px” subhead_font=”||||||||” background_color=”#ef916b” background_image=”https:\/\/pdi.ro\/2021\/wp-content\/uploads\/2021\/05\/PDI2021_header_1920x550px.jpg” background_blend=”luminosity” background_layout=”light” custom_margin=”0px||8px” custom_padding=”40px||40px||true” content_font_size_tablet=”” content_font_size_phone=”15px” content_font_size_last_edited=”on|desktop”][\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.4.8″][et_pb_row column_structure=”2_5,3_5″ _builder_version=”3.25″ locked=”off”][et_pb_column type=”2_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/pdi.ro\/2021\/wp-content\/uploads\/2021\/07\/Brihan-Ilarie_1-e1626241421432.jpg” title_text=”Brihan Ilarie_1″ align=”center” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.9.7″ max_width=”25%” border_radii=”on|100px|100px|100px|100px”][\/et_pb_image][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.7″ hover_enabled=”0″ sticky_enabled=”0″]<\/p>\n

<\/strong><\/span><\/h4>\n

\u0218ef Lucr. Dr. Brihan Ilarie
Facultatea de Medicin\u0103, Universitatea din Oradea, Rom\u00e2nia
Spitalul Clinic Jude\u021bean de Urgen\u021b\u0103 Oradea<\/p>\n

<\/strong><\/span><\/h4>\n

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Simpozion Sandoz: Erelzi \u0219i Hyrimoz, dou\u0103 tratamente, un singur dispozitiv, SensoReadyPen
Lectori: Simona Iano\u0219i, Ilarie Brihan<\/span><\/p>\n

Medicamentele biosimilare devin disponibile \u00een diferite arii terapeutice. Un medicament biosimilar este un medicament biologic, care s-a dovedit a nu avea diferen\u021be clinic semnificative fa\u021b\u0103 de medicamentul de referin\u021b\u0103 \u00een ceea ce prive\u0219te calitatea, activitatea biologic\u0103, siguran\u021ba, eficacitatea \u0219i imunogenitatea.1 Medicamentele biosimilare au fost utilizate \u00een practica clinic\u0103 de peste 15 ani ca tratamente pentru \u00eenlocuirea hormonului de cre\u0219tere, pentru neutropenie \u0219i anemie legate de insuficien\u021ba renal\u0103 cronic\u0103 sau de cancer.
Concuren\u021ba \u00eentre diferite medicamente biologice, inclusiv medicamentele biosimilare, creeaz\u0103 mai multe oportunit\u0103\u021bi de alegere a tratamentului pentru medici \u0219i pentru pacien\u021bi \u0219i \u00eembun\u0103t\u0103\u021be\u0219te performan\u021ba pentru medicamente individuale (cum ar fi dispozitive \u00eembun\u0103t\u0103\u021bite, servicii pentru pacien\u021bi sau formul\u0103ri).
Prescriptorii ar trebui s\u0103 utilizeze toate dovezile relevante disponibile pentru a lua deciziile privind \u00eengrijirea unui pacient, cu selec\u021bia ini\u021bial\u0103 a celei mai potrivite molecule pe baza considerentelor clinice. Ulterior, medicii care prescriu medicamente ar trebui s\u0103 ia \u00een considerare propunerile de valoare oferite de diferite produse, inclusiv indica\u021biile privind costurile \u0219i licen\u021bele, precum \u0219i al\u021bi factori relevan\u021bi pentru utilizarea produsului \u0219i rezultatele clinice probabile pentru fiecare pacient.
Produsele biosimilare sunt considerate a fi interschimbabile cu produsul lor de referin\u021b\u0103, ceea ce \u00eenseamn\u0103 c\u0103 un medic poate alege medicamentul biosimilar \u00een locul produsului de referin\u021b\u0103 (sau invers) \u0219i se a\u0219teapt\u0103 s\u0103 ob\u021bin\u0103 acela\u0219i efect clinic (echivalen\u021b\u0103 terapeutic\u0103).1
Compania Sandoz, care a aniversat anul acesta 15 ani de la producerea primului biosimilar din lume, de hormon de cre\u0219tere (Omnitrope), pune la dispozi\u021bia medicilor \u0219i pacien\u021bilor din Romania un portofoliu complet de biosimilare pentru tratamentul bolilor inflamatorii autoimune, de la adalimumab (Hyrimoz) la etanercept (Erelzi), folosing acela\u0219i dispozitiv inovator de administrare SensoReadyPen, infliximab (Zessly) si rituximab (Rixathon).<\/p>\n

Simpozion Sandoz: Erelzi and Hyrimoz, two treatments, one device, SensoReadyPen
Lectori: Simona Iano\u0219i, Ilarie Brihan<\/span><\/p>\n

Biosimilar medicines are becoming available across different therapeutic areas. A biosimilar medicine is a biological medicine, which has been shown not to have any clinically meaningful differences from the reference medicine in terms of quality, biological activity, safety, efficacy and immunogenicity.1 Biosimilar medicines have been used in clinical practice for over 15 years as treatments for growth hormone replacement, neutropenia and anemia related to chronic renal failure or cancer.
Competition between different biological medicines, including biosimilar medicines, creates increased choice for patients and clinicians, and enhanced value propositions for individual medicines (such as improved devices, patient services or formulations).2
Prescribers should use all available relevant evidence to guide decisions about the care of an individual patient with the initial selection of the most appropriate molecule based on clinical considerations. Subsequently, prescribers should consider the value propositions offered by different products, including cost and licensed indications, as well as other factors relevant to the use of the product and likely clinical outcomes for each patient.
Biosimilar products are considered interchangeable with their reference product; which means a prescriber can choose the biosimilar medicine over the reference product (or vice versa) and expect to achieve the same clinical effect (therapeutic equivalence)1
Sandoz with over 15 years experience in producing biosimilars, starting with first worldwide biosimilar, growth hormone (Omnitrope), is offering to doctors and patients in Romania a complete portfolio of biosimilars in inflammatory autoimmune diseases, from adalimumab (Hyrimoz) to etanercept (Erelzi), sharing the same innovative administration device SensoReadyPen, infliximab (Zessly), and rituximab (Rixathon).<\/p>\n

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Contacteaz\u0103 operatorul PDI 2021<\/p>\n

[\/et_pb_text][et_pb_contact_form email=”contact@pdi.ro\/2021\/2019″ submit_button_text=”Trimite mesajul” _builder_version=”4.9.4″ title_font=”||||||||” custom_button=”on” button_text_color=”#F0622A”][et_pb_contact_field field_id=”Name” field_title=”Nume” _builder_version=”3.18.9″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Email” field_title=”Adresa de e-mail” field_type=”email” _builder_version=”3.19.4″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Message” field_title=”Mesajul dvs.” field_type=”text” fullwidth_field=”on” _builder_version=”3.18.9″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][\/et_pb_contact_form][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.4″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark”]<\/p>\n

Operatorul PDI 2021<\/p>\n

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\"\"<\/span><\/p>\n

<\/span><\/p>\n

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Adresa: Str. A. Panu nr. 13, Iasi<\/span>
Tel.: 0332.40.88.00-05<\/span>
E-mail: inscrieri@primaderma.ro<\/a>
<\/span>Website:\u00a0<\/span>www.eventernet.ro<\/a><\/p>\n

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Parteneri Media<\/p>\n

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\u0218ef Lucr. Dr. Brihan IlarieFacultatea de Medicin\u0103, Universitatea din Oradea, Rom\u00e2niaSpitalul Clinic Jude\u021bean de Urgen\u021b\u0103 Oradea  Simpozion Sandoz: Erelzi \u0219i Hyrimoz, dou\u0103 tratamente, un singur dispozitiv, SensoReadyPenLectori: Simona Iano\u0219i, Ilarie Brihan Medicamentele biosimilare devin disponibile \u00een diferite arii terapeutice. Un medicament biosimilar este un medicament biologic, care s-a dovedit a nu avea diferen\u021be clinic semnificative […]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-10384","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/10384","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/comments?post=10384"}],"version-history":[{"count":7,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/10384\/revisions"}],"predecessor-version":[{"id":10569,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/10384\/revisions\/10569"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/media?parent=10384"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}