{"id":10637,"date":"2021-07-17T16:48:41","date_gmt":"2021-07-17T14:48:41","guid":{"rendered":"https:\/\/primaderma.ro\/?page_id=10637"},"modified":"2021-07-17T16:54:27","modified_gmt":"2021-07-17T14:54:27","slug":"dr-alina-elena-spinu","status":"publish","type":"page","link":"https:\/\/pdi.ro\/2021\/dr-alina-elena-spinu\/","title":{"rendered":"Dr. Alina Elena Sp\u00eenu"},"content":{"rendered":"

[et_pb_section fb_built=”1″ fullwidth=”on” disabled_on=”on|off|off” _builder_version=”3.22″ custom_margin=”||” custom_padding=”15px||29px” top_divider_style=”waves2″ top_divider_color=”#f0622a” top_divider_flip=”horizontal|vertical” bottom_divider_style=”waves2″ bottom_divider_color=”#fcdedb” bottom_divider_height=”105px” bottom_divider_flip=”vertical” global_module=”9062″ collapsed=”off”][et_pb_fullwidth_header title=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF90aXRsZSIsInNldHRpbmdzIjp7ImJlZm9yZSI6IiIsImFmdGVyIjoiIn19@” text_orientation=”right” header_image_url=”https:\/\/pdi.ro\/2021\/wp-content\/uploads\/2021\/05\/PDI2021_logo_header_int_600x300px.png” disabled_on=”on|on|off” _builder_version=”4.9.4″ _dynamic_attributes=”title” title_font=”Kaushan Script||||||||” title_text_align=”right” title_text_color=”#f0622a” title_font_size=”50px” content_font=”|600||on|||||” content_text_align=”center” content_text_color=”#686766″ content_font_size=”15px” subhead_font=”||||||||” background_color=”#ef916b” background_image=”https:\/\/pdi.ro\/2021\/wp-content\/uploads\/2021\/05\/PDI2021_header_1920x550px.jpg” background_blend=”luminosity” background_layout=”light” custom_margin=”0px||8px” custom_padding=”40px||40px||true” content_font_size_tablet=”” content_font_size_phone=”15px” content_font_size_last_edited=”on|desktop”][\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22″ locked=”off”][et_pb_row column_structure=”2_5,3_5″ _builder_version=”3.25″][et_pb_column type=”2_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/pdi.ro\/2021\/wp-content\/uploads\/2021\/07\/SpinuAlina-Elena-web.jpg” title_text=”Sp\u00eenuAlina Elena web” align=”center” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.9.7″ max_width=”31%” hover_enabled=”0″ border_radii=”on|100px|100px|100px|100px” sticky_enabled=”0″][\/et_pb_image][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.7″ hover_enabled=”0″ sticky_enabled=”0″]<\/p>\n

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Dr. Alina Elena Sp\u00eenu<\/span><\/strong>
Departamentul de Dermatologie, Spitalul CF Ia\u0219i<\/span><\/strong><\/h4>\n

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Leziunile erozive orale \u2013 o continu\u0103 provocare \u00een practica dermatologic\u0103
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Autori: Alina Elena Sp\u00eenu1, Daciana Elena Br\u0103ni\u0219teanu2, Anastasia Vicovan1, Diana \u0218tefania D\u00eerzu1, Andreea Corina Dr\u0103goi1, \u0218tefana Maria Cap\u0219a1, Roxana Bilib\u0103u1, Andreea Tucaliuc1, Isabela Alexandra Fartu\u0219nic1, C\u0103t\u0103lina Cojocaru1, Mihaela Paula Toader3
1Clinica de Dermatologie, Spitalul Clinic CF Ia\u0219i, Rom\u00e2nia
2Disciplina Dermatologie, Facultatea de Medicin\u0103 General\u0103, U.M.F. \u201dGrigore T. Popa\u201d Ia\u0219i, Rom\u00e2nia
3Disciplina Dermatologie oral\u0103, Facultatea de Medicin\u0103 Dentar\u0103, U.M.F. \u201dGrigore T. Popa\u201d Ia\u0219i, Rom\u00e2nia<\/p>\n

Cuvinte cheie: napkin, psoriazis, nou-n\u0103scut, provocare, tratament<\/p>\n

Leziunile erozive ale cavit\u0103\u021bii orale sunt o prezentare clinic\u0103 comun\u0103, nespecific\u0103, a unui spectru larg de patologii de natur\u0103 \u0219i severitate foarte diferite, astfel \u00eenc\u00e2t diagnosticul pozitiv este deseori o adev\u0103rat\u0103 provocare pentru clinician. Prezent\u0103m cazul unei paciente \u00een v\u00e2rst\u0103 de 30 de ani, cunoscut\u0103 cu alergie confirmat\u0103 prin patch-test la materiale de restaurare dentar\u0103, cu implanturi dentare metalice, care s-a internat pentru plaje erozive intens dureroase, par\u021bial acoperite de pseudomembrane localizate la nivelul cavit\u0103\u021bii orale, cu extindere vermilionar\u0103, \u00eenso\u021bite de disfagie \u0219i dificult\u0103\u021bi \u00een alimenta\u021bie. Aspectul clinic nespecific \u0219i absen\u021ba leziunilor cutanate asociate, a impus efectuarea examenului histopatologic \u0219i detectarea anticorpilor circulan\u021bi anti Dsg-1 \u0219i anti Dsg-3 prin metoda ELISA, care au stabilit diagnosticul de pemfigus oral. Pemfigusul este o boal\u0103 autoimun\u0103 cronic\u0103 sever\u0103, cu poten\u021bial risc vital, care debuteaz\u0103 \u00een 60% din cazuri la nivelul cavit\u0103\u021bii orale, moment \u00een care se afl\u0103 la grani\u021ba dintre specialit\u0103\u021bi. Diagnosticul precoce necesit\u0103 un grad mare de suspiciune clinic\u0103 \u0219i impune nevoia elabor\u0103rii unui algoritm de diagnostic. De\u0219i leziunile erozive de la nivelul cavit\u0103\u021bii orale \u00een absen\u021ba manifest\u0103rilor tegumentare sunt dificil de diagnosticat, medicul dermatolog are un rol cheie \u00een gestionarea acestor cazuri.<\/p>\n

Oral erosive lesions – a continuous challenge in dermatological practice
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Authors: Alina Elena Sp\u00eenu1, Daciana Elena Br\u0103ni\u0219teanu2, Anastasia Vicovan1, Diana \u0218tefania D\u00eerzu1, Andreea Corina Dr\u0103goi1, \u0218tefana Maria Cap\u0219a1, Roxana Bilib\u0103u1, Andreea Tucaliuc1, Isabela Alexandra Fartu\u0219nic1, C\u0103t\u0103lina Cojocaru1, Mihaela Paula Toader3<\/p>\n

1Department of Dermatology, \u201cRailway Clinical Hospital\u201d, Iasi, Romania
2Department of Dermatology, \u201cGrigore T. Popa\u201d University of Medicine and Pharmacy, Iasi, Romania
3Department of Oral Dermatology, \u201cGrigore T. Popa\u201d University of Medicine and Pharmacy, Iasi, Romania<\/p>\n

Keywords: oral erosions, oral pemphigus, antidesmoglein antibodies<\/p>\n

Erosive lesions of the oral cavity are a common, nonspecific clinical presentation of a wide range of morbid conditions of very different nature and severity, making the positive diagnosis a real challenge for the clinician. We present the case of a 30-year-old patient, known with allergy to metallic dental restoration materials confirmed by cutaneous patch-tests, with metallic dental implants, who was hospitalized for extensive, intensely painful erosive lesions, partially covered by pseudomembranes located on the oral mucosa, with vermillion involvement, accompanied by dysphagia and eating difficulties. The non-specific clinical appearance and the absence of associated skin lesions required histopathological examination and detection of circulating anti-Dsg-1 and anti-Dsg-3 antibodies by ELISA method, which established the diagnosis of oral pemphigus. Pemphigus is a severe potentially life-threatening, chronic autoimmune disease, with onset on the oral mucosa in 60% of cases. In the absence of cutaneous lesions, the diagnosis lies at the border between specialties. Early diagnosis requires a high degree of clinical suspicion and imposes the need to develop a diagnostic algorithm. Although erosive lesions in the oral cavity in the absence of skin manifestations are difficult to diagnose, the dermatologist has a key role in managing these cases.<\/p>\n

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Contacteaz\u0103 operatorul PDI 2021<\/p>\n

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Operatorul PDI 2021<\/p>\n

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\"\"<\/span><\/p>\n

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Adresa: Str. A. Panu nr. 13, Iasi<\/span>
Tel.: 0332.40.88.00-05<\/span>
E-mail: inscrieri@primaderma.ro<\/a>
<\/span>Website:\u00a0<\/span>www.eventernet.ro<\/a><\/p>\n

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Parteneri Media<\/p>\n

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Dr. Alina Elena Sp\u00eenuDepartamentul de Dermatologie, Spitalul CF Ia\u0219iLeziunile erozive orale \u2013 o continu\u0103 provocare \u00een practica dermatologic\u0103 Autori: Alina Elena Sp\u00eenu1, Daciana Elena Br\u0103ni\u0219teanu2, Anastasia Vicovan1, Diana \u0218tefania D\u00eerzu1, Andreea Corina Dr\u0103goi1, \u0218tefana Maria Cap\u0219a1, Roxana Bilib\u0103u1, Andreea Tucaliuc1, Isabela Alexandra Fartu\u0219nic1, C\u0103t\u0103lina Cojocaru1, Mihaela Paula Toader31Clinica de Dermatologie, Spitalul Clinic CF Ia\u0219i, Rom\u00e2nia2Disciplina […]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-10637","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/10637","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/comments?post=10637"}],"version-history":[{"count":2,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/10637\/revisions"}],"predecessor-version":[{"id":10640,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/10637\/revisions\/10640"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/media?parent=10637"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}