<\/strong><\/span><\/h4>\n<\/strong><\/span><\/h4>\nProf. Univ. Dr. Alecu Mihail<\/strong><\/span>
Spitalul Clinic de Boli Infec\u0163ioase \u015fi Tropicale “Dr. Victor Babe\u015f\u201d Bucure\u015fti<\/strong><\/span>
Universitatea “Titu Maiorescu” Facultatea de Medicin\u0103, Bucure\u015fti<\/strong><\/span><\/h4>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”3.25″ locked=”off”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.7″ hover_enabled=”0″ sticky_enabled=”0″]<\/p>\n
Manifest\u0103ri alergice \u0219i non alergice post vaccinare anti SARS CoV2<\/span>
Autori: M. Alecu1 , Gabriela Coman2, Alina Mu\u0219etescu1, Ionica R\u0103dulescu1<\/span>
1Universitatea “Titu Maiorescu”, Facultatea de Medicin\u0103, Bucure\u0219ti, Rom\u00e2nia
2Spitalul Clinic de Boli Infec\u021bioase \u0219i Tropicale “Dr. Victor Babe\u0219”, Bucure\u0219ti, Rom\u00e2nia<\/p>\nCuvinte cheie: reac\u021bii adverse, vaccin, SARS COV2
Administrarea \u00een mas\u0103 \u00eentr-un interval scurt de timp a vaccinurilor \u00eempotriva virusului Sars Cov2 necesit\u0103 cunoa\u0219terea aprofundat\u0103 \u0219i rapid\u0103 a reac\u021biilor adverse produse de aceste vaccinuri.
Datele ob\u021binute din studiile clinice efectuate \u00eenaintea administr\u0103rii vaccinurilor trebuie corelate cu datele ob\u021binute de la persoanele vaccinate p\u00e2n\u0103 \u00een prezent. Pe de alt\u0103 parte, frecven\u021ba \u0219i gravitatea reac\u021biilor adverse la pacien\u021bii vaccina\u021bi trebuie comparat\u0103 cu apari\u021bia spontan\u0103 a acestor reac\u021bii \u00een popula\u021bia normal\u0103, nevaccinat\u0103.
Vaccinurile anti Sars Cov 2 utilizate \u00een prezent, at\u00e2t cele cu ARNm (Pfizer, Moderna) c\u00e2t \u0219i cele cu vector viral ((Janssen) produc reac\u021bii adverse cu aspecte clinice multiple dar cu grade de gravitate diverse, cele mai multe fiind reac\u021bii minore, care nu pun \u00een pericol via\u021ba pacien\u021bilor.
\u00cen studiul nostru se face o prezentare general\u0103 a reac\u021biilor alergice \u00eent\u00e2lnite la aceste vaccinuri (\u0219ocul anafilactic, edemul Quinque), a reac\u021biilor nealergice (autoimunitatea), a inflama\u021biei \u0219i reac\u021biilor cu mecanism incert. Sunt prezentate mecanismele de producere a reac\u021biilor adverse \u00eent\u00e2lnite, aspecte terapeutice ca \u0219i frecven\u021ba cu care apar aceste reac\u021bii comparativ cu popula\u021bia normal\u0103, nevaccinat\u0103. \u00cen final, pe baza acestor date, \u0219i a raportului risc\/beneficiu, se face o analiz\u0103 a deciziei de recomandare, utilizare sau interzicere a vaccinurilor \u00een situa\u021bii normale sau la pacien\u021bii cu situa\u021bii clinice deosebite.<\/p>\n
Allergic and non-allergic manifestations post vaccination anti SARS CoV2<\/span>
Autori: M. Alecu1, Gabriela Coman2, Alina Mu\u0219etescu1, Ionica R\u0103dulescu1<\/span>
1″Titu Maiorescu” University, Faculty of Medicine, Bucharest, Romania
2″Dr. Victor Babe\u0219” Infectious and Tropical Diseases Clinical Hospital, Bucharest, Romania<\/p>\nKeywords: side effects, vaccine, SARS COV2
Mass administration of Sars Cov2 virus vaccines in a short period of time requires a thorough and rapid understanding of the adverse reactions produced by these vaccines.
Data obtained from clinical trials performed prior to vaccination should be correlated with data obtained from vaccinated individuals to date. On the other hand, the frequency and severity of adverse reactions in vaccinated patients should be compared with the spontaneous occurrence of these reactions in the normal, unvaccinated population.
The Sars Cov 2 vaccines currently used, both those with mRNA (Pfizer, Moderna) and those with viral vector (Janssen) produce side effects with multiple clinical aspects but with varying degrees of severity, most of which are minor reactions, which they do not endanger the lives of patients.
Our study provides an overview of allergic reactions to these vaccines (anaphylactic shock, Quinque edema), non-allergic reactions (autoimmunity), inflammation and reactions with an uncertain mechanism. The mechanisms of production of the adverse reactions encountered are presented, therapeutic aspect as well as the frequency with which these reactions appear compared to the normal, unvaccinated population. Finally, based on these data, and the risk & benefit ratio, an analysis is made of the decision to recommend, use or prohibit vaccines in normal situations or in patients with special clinical situations.<\/p>\n
Scurt CV<\/span><\/p>\nStudii:<\/strong> Facultatea de Medicin\u0103 Bucure\u0219ti
Specialitatea<\/strong>: Medicin\u0103 general\u0103
Titluri didactice, \u0219tiin\u021bifice \u0219i academice<\/strong>
Cercetator \u0219tiin\u021bific principal gradul I
Doctor \u00een medicin\u0103 cu teza \u201dCitochinele \u00een tratamentul local al unor tumori maligne cutanate\u201d (1994), UMF Bucure\u0219ti
Profesor titular de curs Dermato-venerologie, Univ. Titu Maiorescu, Bucure\u0219ti
Specialitate:<\/strong> – medic primar dermato-venerologie
medic primar alergologie \u0219i imunologie clinic\u0103
Membru \u00een asocia\u021bii profesionale, academii:<\/strong>
Societatea Rom\u00e2na de Dermatologie
Societatea Rom\u00e2na de Alergologie \u0219i Imunologie Clinica
ISIR (Asocia\u021bia Interna\u021bionala de Studiu a Interferonului \u0219i a citokinelor)
EADV (Asocia\u021bia Europeana de Dermato-Venerologie) Distinc\u021bii :
Premiul Academiei Rom\u00e2ne \u201d Daniel Danielopolu\u201d – 1990
Premiul Conferin\u021bei Interbalcanice de alergologie -Bucuresti \u2014 1995 e Premiul Academiei Rom\u00e2ne \u201dGheorghe Marinescu\u201d \u2013 2001
\u00cencadrarea prezenta \u0219i cea anterioara:<\/strong>
Bucure\u0219ti, Spitalul Clinic de Boli Infec\u021bioase \u0219i Tropicale Dr. Victor Babe\u0219 Laboratorul de
Imunologie, din 1981 p\u00e2na in prezent \u2014 Conducator Laborator Imunologie
Lucrari \u0219tiin\u021bifice publicate:<\/strong>
-un numar de 100 de comunic\u0103ri \u0219i articole dintre care 25 articole publicate \u00een reviste de specialitate de circula\u021bie interna\u021bional\u0103, indexate
monografii: \u201dSarcomul Kaposi\u201d Editura Tehnic\u0103, 1998, 230 pagini, unic autor \u201dApoptoza-Moartea celular\u0103 programat\u0103\u201d Ed. Academiei, 1999, 410 pagini, coautor Reac\u021bii alergice la medicamente\u201d Ed. Medical\u0103, 2002, 400 pagini, prim autor \u201dPatologia molecular\u0103 a pielii\u201d Ed. Medical\u0103, 2006, 495 pagini, unic autor \u201dDermato-Venerologie\u201d Ed. Didactic\u0103 \u0219i Pedagogic\u0103 2010, 300 pagini<\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.9.6″ background_color=”rgba(117,194,33,0.23)” background_image=”https:\/\/pdi.ro\/2021\/wp-content\/uploads\/2021\/05\/PDI2021_header_1920x550px.jpg” background_blend=”multiply” custom_padding=”54px|0px|0|0px|false|false” top_divider_style=”waves2″ top_divider_color=”#ffffff” top_divider_height=”155px” top_divider_height_tablet=”” top_divider_height_phone=”97px” top_divider_height_last_edited=”on|desktop” bottom_divider_style=”waves2″ bottom_divider_color=”#75c221″ bottom_divider_flip=”vertical” bottom_divider_height_tablet=”” bottom_divider_height_phone=”59px” bottom_divider_height_last_edited=”on|desktop” global_module=”9177″ saved_tabs=”all”][et_pb_row column_structure=”3_5,2_5″ _builder_version=”3.25″ custom_padding=”61px|0px|69px|0px|false|false”][et_pb_column type=”3_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.4″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” text_line_height=”1.2em” header_font=”||||||||” background_layout=”dark” text_font_size_tablet=”” text_font_size_phone=”” text_font_size_last_edited=”on|desktop”]<\/p>\n
Contacteaz\u0103 operatorul PDI 2021<\/p>\n
[\/et_pb_text][et_pb_contact_form email=”contact@pdi.ro\/2021\/2019″ submit_button_text=”Trimite mesajul” _builder_version=”4.9.4″ title_font=”||||||||” custom_button=”on” button_text_color=”#F0622A”][et_pb_contact_field field_id=”Name” field_title=”Nume” _builder_version=”3.18.9″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Email” field_title=”Adresa de e-mail” field_type=”email” _builder_version=”3.19.4″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Message” field_title=”Mesajul dvs.” field_type=”text” fullwidth_field=”on” _builder_version=”3.18.9″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][\/et_pb_contact_form][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.4″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark”]<\/p>\n
Operatorul PDI 2021<\/p>\n
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![\"\"](\"https:\/\/pdi.ro\/2021\/wp-content\/uploads\/2020\/02\/eventer_logo_150px.png\")
<\/span><\/p>\n<\/span><\/p>\n<\/span><\/p>\nAdresa: Str. A. Panu nr. 13, Iasi<\/span>
Tel.: 0332.40.88.00-05<\/span>
E-mail: inscrieri@primaderma.ro<\/a>
<\/span>Website:\u00a0<\/span>www.eventernet.ro<\/a><\/p>\n[\/et_pb_text][et_pb_text disabled_on=”off|off|off” _builder_version=”4.0.11″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” locked=”off”]<\/p>\n
Parteneri Media<\/p>\n
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Prof. Univ. Dr. Alecu Mihail Spitalul Clinic de Boli Infec\u0163ioase \u015fi Tropicale “Dr. Victor Babe\u015f\u201d Bucure\u015fti Universitatea “Titu Maiorescu” Facultatea de Medicin\u0103, Bucure\u015ftiManifest\u0103ri alergice \u0219i non alergice post vaccinare anti SARS CoV2Autori: M. Alecu1 , Gabriela Coman2, Alina Mu\u0219etescu1, Ionica R\u0103dulescu11Universitatea “Titu Maiorescu”, Facultatea de Medicin\u0103, Bucure\u0219ti, Rom\u00e2nia2Spitalul Clinic de Boli Infec\u021bioase \u0219i Tropicale “Dr. […]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-7441","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/7441","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/comments?post=7441"}],"version-history":[{"count":10,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/7441\/revisions"}],"predecessor-version":[{"id":10165,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/7441\/revisions\/10165"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/media?parent=7441"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Prof. Univ. Dr. Alecu Mihail<\/strong><\/span>
Spitalul Clinic de Boli Infec\u0163ioase \u015fi Tropicale “Dr. Victor Babe\u015f\u201d Bucure\u015fti<\/strong><\/span>
Universitatea “Titu Maiorescu” Facultatea de Medicin\u0103, Bucure\u015fti<\/strong><\/span><\/h4>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”3.25″ locked=”off”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.7″ hover_enabled=”0″ sticky_enabled=”0″]<\/p>\n
Manifest\u0103ri alergice \u0219i non alergice post vaccinare anti SARS CoV2<\/span>
Autori: M. Alecu1 , Gabriela Coman2, Alina Mu\u0219etescu1, Ionica R\u0103dulescu1<\/span>
1Universitatea “Titu Maiorescu”, Facultatea de Medicin\u0103, Bucure\u0219ti, Rom\u00e2nia
2Spitalul Clinic de Boli Infec\u021bioase \u0219i Tropicale “Dr. Victor Babe\u0219”, Bucure\u0219ti, Rom\u00e2nia<\/p>\nCuvinte cheie: reac\u021bii adverse, vaccin, SARS COV2
Administrarea \u00een mas\u0103 \u00eentr-un interval scurt de timp a vaccinurilor \u00eempotriva virusului Sars Cov2 necesit\u0103 cunoa\u0219terea aprofundat\u0103 \u0219i rapid\u0103 a reac\u021biilor adverse produse de aceste vaccinuri.
Datele ob\u021binute din studiile clinice efectuate \u00eenaintea administr\u0103rii vaccinurilor trebuie corelate cu datele ob\u021binute de la persoanele vaccinate p\u00e2n\u0103 \u00een prezent. Pe de alt\u0103 parte, frecven\u021ba \u0219i gravitatea reac\u021biilor adverse la pacien\u021bii vaccina\u021bi trebuie comparat\u0103 cu apari\u021bia spontan\u0103 a acestor reac\u021bii \u00een popula\u021bia normal\u0103, nevaccinat\u0103.
Vaccinurile anti Sars Cov 2 utilizate \u00een prezent, at\u00e2t cele cu ARNm (Pfizer, Moderna) c\u00e2t \u0219i cele cu vector viral ((Janssen) produc reac\u021bii adverse cu aspecte clinice multiple dar cu grade de gravitate diverse, cele mai multe fiind reac\u021bii minore, care nu pun \u00een pericol via\u021ba pacien\u021bilor.
\u00cen studiul nostru se face o prezentare general\u0103 a reac\u021biilor alergice \u00eent\u00e2lnite la aceste vaccinuri (\u0219ocul anafilactic, edemul Quinque), a reac\u021biilor nealergice (autoimunitatea), a inflama\u021biei \u0219i reac\u021biilor cu mecanism incert. Sunt prezentate mecanismele de producere a reac\u021biilor adverse \u00eent\u00e2lnite, aspecte terapeutice ca \u0219i frecven\u021ba cu care apar aceste reac\u021bii comparativ cu popula\u021bia normal\u0103, nevaccinat\u0103. \u00cen final, pe baza acestor date, \u0219i a raportului risc\/beneficiu, se face o analiz\u0103 a deciziei de recomandare, utilizare sau interzicere a vaccinurilor \u00een situa\u021bii normale sau la pacien\u021bii cu situa\u021bii clinice deosebite.<\/p>\n
Allergic and non-allergic manifestations post vaccination anti SARS CoV2<\/span>
Autori: M. Alecu1, Gabriela Coman2, Alina Mu\u0219etescu1, Ionica R\u0103dulescu1<\/span>
1″Titu Maiorescu” University, Faculty of Medicine, Bucharest, Romania
2″Dr. Victor Babe\u0219” Infectious and Tropical Diseases Clinical Hospital, Bucharest, Romania<\/p>\nKeywords: side effects, vaccine, SARS COV2
Mass administration of Sars Cov2 virus vaccines in a short period of time requires a thorough and rapid understanding of the adverse reactions produced by these vaccines.
Data obtained from clinical trials performed prior to vaccination should be correlated with data obtained from vaccinated individuals to date. On the other hand, the frequency and severity of adverse reactions in vaccinated patients should be compared with the spontaneous occurrence of these reactions in the normal, unvaccinated population.
The Sars Cov 2 vaccines currently used, both those with mRNA (Pfizer, Moderna) and those with viral vector (Janssen) produce side effects with multiple clinical aspects but with varying degrees of severity, most of which are minor reactions, which they do not endanger the lives of patients.
Our study provides an overview of allergic reactions to these vaccines (anaphylactic shock, Quinque edema), non-allergic reactions (autoimmunity), inflammation and reactions with an uncertain mechanism. The mechanisms of production of the adverse reactions encountered are presented, therapeutic aspect as well as the frequency with which these reactions appear compared to the normal, unvaccinated population. Finally, based on these data, and the risk & benefit ratio, an analysis is made of the decision to recommend, use or prohibit vaccines in normal situations or in patients with special clinical situations.<\/p>\n
Scurt CV<\/span><\/p>\nStudii:<\/strong> Facultatea de Medicin\u0103 Bucure\u0219ti
Specialitatea<\/strong>: Medicin\u0103 general\u0103
Titluri didactice, \u0219tiin\u021bifice \u0219i academice<\/strong>
Cercetator \u0219tiin\u021bific principal gradul I
Doctor \u00een medicin\u0103 cu teza \u201dCitochinele \u00een tratamentul local al unor tumori maligne cutanate\u201d (1994), UMF Bucure\u0219ti
Profesor titular de curs Dermato-venerologie, Univ. Titu Maiorescu, Bucure\u0219ti
Specialitate:<\/strong> – medic primar dermato-venerologie
medic primar alergologie \u0219i imunologie clinic\u0103
Membru \u00een asocia\u021bii profesionale, academii:<\/strong>
Societatea Rom\u00e2na de Dermatologie
Societatea Rom\u00e2na de Alergologie \u0219i Imunologie Clinica
ISIR (Asocia\u021bia Interna\u021bionala de Studiu a Interferonului \u0219i a citokinelor)
EADV (Asocia\u021bia Europeana de Dermato-Venerologie) Distinc\u021bii :
Premiul Academiei Rom\u00e2ne \u201d Daniel Danielopolu\u201d – 1990
Premiul Conferin\u021bei Interbalcanice de alergologie -Bucuresti \u2014 1995 e Premiul Academiei Rom\u00e2ne \u201dGheorghe Marinescu\u201d \u2013 2001
\u00cencadrarea prezenta \u0219i cea anterioara:<\/strong>
Bucure\u0219ti, Spitalul Clinic de Boli Infec\u021bioase \u0219i Tropicale Dr. Victor Babe\u0219 Laboratorul de
Imunologie, din 1981 p\u00e2na in prezent \u2014 Conducator Laborator Imunologie
Lucrari \u0219tiin\u021bifice publicate:<\/strong>
-un numar de 100 de comunic\u0103ri \u0219i articole dintre care 25 articole publicate \u00een reviste de specialitate de circula\u021bie interna\u021bional\u0103, indexate
monografii: \u201dSarcomul Kaposi\u201d Editura Tehnic\u0103, 1998, 230 pagini, unic autor \u201dApoptoza-Moartea celular\u0103 programat\u0103\u201d Ed. Academiei, 1999, 410 pagini, coautor Reac\u021bii alergice la medicamente\u201d Ed. Medical\u0103, 2002, 400 pagini, prim autor \u201dPatologia molecular\u0103 a pielii\u201d Ed. Medical\u0103, 2006, 495 pagini, unic autor \u201dDermato-Venerologie\u201d Ed. Didactic\u0103 \u0219i Pedagogic\u0103 2010, 300 pagini<\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.9.6″ background_color=”rgba(117,194,33,0.23)” background_image=”https:\/\/pdi.ro\/2021\/wp-content\/uploads\/2021\/05\/PDI2021_header_1920x550px.jpg” background_blend=”multiply” custom_padding=”54px|0px|0|0px|false|false” top_divider_style=”waves2″ top_divider_color=”#ffffff” top_divider_height=”155px” top_divider_height_tablet=”” top_divider_height_phone=”97px” top_divider_height_last_edited=”on|desktop” bottom_divider_style=”waves2″ bottom_divider_color=”#75c221″ bottom_divider_flip=”vertical” bottom_divider_height_tablet=”” bottom_divider_height_phone=”59px” bottom_divider_height_last_edited=”on|desktop” global_module=”9177″ saved_tabs=”all”][et_pb_row column_structure=”3_5,2_5″ _builder_version=”3.25″ custom_padding=”61px|0px|69px|0px|false|false”][et_pb_column type=”3_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.4″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” text_line_height=”1.2em” header_font=”||||||||” background_layout=”dark” text_font_size_tablet=”” text_font_size_phone=”” text_font_size_last_edited=”on|desktop”]<\/p>\n
Contacteaz\u0103 operatorul PDI 2021<\/p>\n
[\/et_pb_text][et_pb_contact_form email=”contact@pdi.ro\/2021\/2019″ submit_button_text=”Trimite mesajul” _builder_version=”4.9.4″ title_font=”||||||||” custom_button=”on” button_text_color=”#F0622A”][et_pb_contact_field field_id=”Name” field_title=”Nume” _builder_version=”3.18.9″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Email” field_title=”Adresa de e-mail” field_type=”email” _builder_version=”3.19.4″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Message” field_title=”Mesajul dvs.” field_type=”text” fullwidth_field=”on” _builder_version=”3.18.9″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][\/et_pb_contact_form][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.4″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark”]<\/p>\n
Operatorul PDI 2021<\/p>\n
[\/et_pb_text][et_pb_text _builder_version=”4.0.11″ text_font=”||||||||”]<\/p>\n
<\/span><\/p>\n<\/span><\/p>\n<\/span><\/p>\nAdresa: Str. A. Panu nr. 13, Iasi<\/span>
Tel.: 0332.40.88.00-05<\/span>
E-mail: inscrieri@primaderma.ro<\/a>
<\/span>Website:\u00a0<\/span>www.eventernet.ro<\/a><\/p>\n[\/et_pb_text][et_pb_text disabled_on=”off|off|off” _builder_version=”4.0.11″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” locked=”off”]<\/p>\n
Parteneri Media<\/p>\n
[\/et_pb_text][et_pb_gallery gallery_ids=”7203,7204,9252,9464,10156,10157″ fullwidth=”on” _builder_version=”4.9.7″ transform_scale=”86%|86%” max_width=”63%” auto=”on” auto_speed=”3500″ hover_transition_duration=”100ms” hover_transition_delay=”50ms” hover_transition_speed_curve=”ease-in-out” locked=”off”][\/et_pb_gallery][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"
Prof. Univ. Dr. Alecu Mihail Spitalul Clinic de Boli Infec\u0163ioase \u015fi Tropicale “Dr. Victor Babe\u015f\u201d Bucure\u015fti Universitatea “Titu Maiorescu” Facultatea de Medicin\u0103, Bucure\u015ftiManifest\u0103ri alergice \u0219i non alergice post vaccinare anti SARS CoV2Autori: M. Alecu1 , Gabriela Coman2, Alina Mu\u0219etescu1, Ionica R\u0103dulescu11Universitatea “Titu Maiorescu”, Facultatea de Medicin\u0103, Bucure\u0219ti, Rom\u00e2nia2Spitalul Clinic de Boli Infec\u021bioase \u0219i Tropicale “Dr. […]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-7441","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/7441","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/comments?post=7441"}],"version-history":[{"count":10,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/7441\/revisions"}],"predecessor-version":[{"id":10165,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/7441\/revisions\/10165"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/media?parent=7441"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Autori: M. Alecu1 , Gabriela Coman2, Alina Mu\u0219etescu1, Ionica R\u0103dulescu1<\/span>
1Universitatea “Titu Maiorescu”, Facultatea de Medicin\u0103, Bucure\u0219ti, Rom\u00e2nia
2Spitalul Clinic de Boli Infec\u021bioase \u0219i Tropicale “Dr. Victor Babe\u0219”, Bucure\u0219ti, Rom\u00e2nia<\/p>\n
Cuvinte cheie: reac\u021bii adverse, vaccin, SARS COV2
Administrarea \u00een mas\u0103 \u00eentr-un interval scurt de timp a vaccinurilor \u00eempotriva virusului Sars Cov2 necesit\u0103 cunoa\u0219terea aprofundat\u0103 \u0219i rapid\u0103 a reac\u021biilor adverse produse de aceste vaccinuri.
Datele ob\u021binute din studiile clinice efectuate \u00eenaintea administr\u0103rii vaccinurilor trebuie corelate cu datele ob\u021binute de la persoanele vaccinate p\u00e2n\u0103 \u00een prezent. Pe de alt\u0103 parte, frecven\u021ba \u0219i gravitatea reac\u021biilor adverse la pacien\u021bii vaccina\u021bi trebuie comparat\u0103 cu apari\u021bia spontan\u0103 a acestor reac\u021bii \u00een popula\u021bia normal\u0103, nevaccinat\u0103.
Vaccinurile anti Sars Cov 2 utilizate \u00een prezent, at\u00e2t cele cu ARNm (Pfizer, Moderna) c\u00e2t \u0219i cele cu vector viral ((Janssen) produc reac\u021bii adverse cu aspecte clinice multiple dar cu grade de gravitate diverse, cele mai multe fiind reac\u021bii minore, care nu pun \u00een pericol via\u021ba pacien\u021bilor.
\u00cen studiul nostru se face o prezentare general\u0103 a reac\u021biilor alergice \u00eent\u00e2lnite la aceste vaccinuri (\u0219ocul anafilactic, edemul Quinque), a reac\u021biilor nealergice (autoimunitatea), a inflama\u021biei \u0219i reac\u021biilor cu mecanism incert. Sunt prezentate mecanismele de producere a reac\u021biilor adverse \u00eent\u00e2lnite, aspecte terapeutice ca \u0219i frecven\u021ba cu care apar aceste reac\u021bii comparativ cu popula\u021bia normal\u0103, nevaccinat\u0103. \u00cen final, pe baza acestor date, \u0219i a raportului risc\/beneficiu, se face o analiz\u0103 a deciziei de recomandare, utilizare sau interzicere a vaccinurilor \u00een situa\u021bii normale sau la pacien\u021bii cu situa\u021bii clinice deosebite.<\/p>\n
Allergic and non-allergic manifestations post vaccination anti SARS CoV2<\/span> Keywords: side effects, vaccine, SARS COV2 Scurt CV<\/span><\/p>\n Studii:<\/strong> Facultatea de Medicin\u0103 Bucure\u0219ti [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.9.6″ background_color=”rgba(117,194,33,0.23)” background_image=”https:\/\/pdi.ro\/2021\/wp-content\/uploads\/2021\/05\/PDI2021_header_1920x550px.jpg” background_blend=”multiply” custom_padding=”54px|0px|0|0px|false|false” top_divider_style=”waves2″ top_divider_color=”#ffffff” top_divider_height=”155px” top_divider_height_tablet=”” top_divider_height_phone=”97px” top_divider_height_last_edited=”on|desktop” bottom_divider_style=”waves2″ bottom_divider_color=”#75c221″ bottom_divider_flip=”vertical” bottom_divider_height_tablet=”” bottom_divider_height_phone=”59px” bottom_divider_height_last_edited=”on|desktop” global_module=”9177″ saved_tabs=”all”][et_pb_row column_structure=”3_5,2_5″ _builder_version=”3.25″ custom_padding=”61px|0px|69px|0px|false|false”][et_pb_column type=”3_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.4″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” text_line_height=”1.2em” header_font=”||||||||” background_layout=”dark” text_font_size_tablet=”” text_font_size_phone=”” text_font_size_last_edited=”on|desktop”]<\/p>\n Contacteaz\u0103 operatorul PDI 2021<\/p>\n [\/et_pb_text][et_pb_contact_form email=”contact@pdi.ro\/2021\/2019″ submit_button_text=”Trimite mesajul” _builder_version=”4.9.4″ title_font=”||||||||” custom_button=”on” button_text_color=”#F0622A”][et_pb_contact_field field_id=”Name” field_title=”Nume” _builder_version=”3.18.9″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Email” field_title=”Adresa de e-mail” field_type=”email” _builder_version=”3.19.4″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Message” field_title=”Mesajul dvs.” field_type=”text” fullwidth_field=”on” _builder_version=”3.18.9″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][\/et_pb_contact_form][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.4″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark”]<\/p>\n Operatorul PDI 2021<\/p>\n [\/et_pb_text][et_pb_text _builder_version=”4.0.11″ text_font=”||||||||”]<\/p>\n <\/span><\/p>\n <\/span><\/p>\n Adresa: Str. A. Panu nr. 13, Iasi<\/span> [\/et_pb_text][et_pb_text disabled_on=”off|off|off” _builder_version=”4.0.11″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” locked=”off”]<\/p>\n Parteneri Media<\/p>\n [\/et_pb_text][et_pb_gallery gallery_ids=”7203,7204,9252,9464,10156,10157″ fullwidth=”on” _builder_version=”4.9.7″ transform_scale=”86%|86%” max_width=”63%” auto=”on” auto_speed=”3500″ hover_transition_duration=”100ms” hover_transition_delay=”50ms” hover_transition_speed_curve=”ease-in-out” locked=”off”][\/et_pb_gallery][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" Prof. Univ. Dr. Alecu Mihail Spitalul Clinic de Boli Infec\u0163ioase \u015fi Tropicale “Dr. Victor Babe\u015f\u201d Bucure\u015fti Universitatea “Titu Maiorescu” Facultatea de Medicin\u0103, Bucure\u015ftiManifest\u0103ri alergice \u0219i non alergice post vaccinare anti SARS CoV2Autori: M. Alecu1 , Gabriela Coman2, Alina Mu\u0219etescu1, Ionica R\u0103dulescu11Universitatea “Titu Maiorescu”, Facultatea de Medicin\u0103, Bucure\u0219ti, Rom\u00e2nia2Spitalul Clinic de Boli Infec\u021bioase \u0219i Tropicale “Dr. […]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-7441","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/7441","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/comments?post=7441"}],"version-history":[{"count":10,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/7441\/revisions"}],"predecessor-version":[{"id":10165,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/7441\/revisions\/10165"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/media?parent=7441"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Autori: M. Alecu1, Gabriela Coman2, Alina Mu\u0219etescu1, Ionica R\u0103dulescu1<\/span>
1″Titu Maiorescu” University, Faculty of Medicine, Bucharest, Romania
2″Dr. Victor Babe\u0219” Infectious and Tropical Diseases Clinical Hospital, Bucharest, Romania<\/p>\n
Mass administration of Sars Cov2 virus vaccines in a short period of time requires a thorough and rapid understanding of the adverse reactions produced by these vaccines.
Data obtained from clinical trials performed prior to vaccination should be correlated with data obtained from vaccinated individuals to date. On the other hand, the frequency and severity of adverse reactions in vaccinated patients should be compared with the spontaneous occurrence of these reactions in the normal, unvaccinated population.
The Sars Cov 2 vaccines currently used, both those with mRNA (Pfizer, Moderna) and those with viral vector (Janssen) produce side effects with multiple clinical aspects but with varying degrees of severity, most of which are minor reactions, which they do not endanger the lives of patients.
Our study provides an overview of allergic reactions to these vaccines (anaphylactic shock, Quinque edema), non-allergic reactions (autoimmunity), inflammation and reactions with an uncertain mechanism. The mechanisms of production of the adverse reactions encountered are presented, therapeutic aspect as well as the frequency with which these reactions appear compared to the normal, unvaccinated population. Finally, based on these data, and the risk & benefit ratio, an analysis is made of the decision to recommend, use or prohibit vaccines in normal situations or in patients with special clinical situations.<\/p>\n
Specialitatea<\/strong>: Medicin\u0103 general\u0103
Titluri didactice, \u0219tiin\u021bifice \u0219i academice<\/strong>
Cercetator \u0219tiin\u021bific principal gradul I
Doctor \u00een medicin\u0103 cu teza \u201dCitochinele \u00een tratamentul local al unor tumori maligne cutanate\u201d (1994), UMF Bucure\u0219ti
Profesor titular de curs Dermato-venerologie, Univ. Titu Maiorescu, Bucure\u0219ti
Specialitate:<\/strong> – medic primar dermato-venerologie
medic primar alergologie \u0219i imunologie clinic\u0103
Membru \u00een asocia\u021bii profesionale, academii:<\/strong>
Societatea Rom\u00e2na de Dermatologie
Societatea Rom\u00e2na de Alergologie \u0219i Imunologie Clinica
ISIR (Asocia\u021bia Interna\u021bionala de Studiu a Interferonului \u0219i a citokinelor)
EADV (Asocia\u021bia Europeana de Dermato-Venerologie) Distinc\u021bii :
Premiul Academiei Rom\u00e2ne \u201d Daniel Danielopolu\u201d – 1990
Premiul Conferin\u021bei Interbalcanice de alergologie -Bucuresti \u2014 1995 e Premiul Academiei Rom\u00e2ne \u201dGheorghe Marinescu\u201d \u2013 2001
\u00cencadrarea prezenta \u0219i cea anterioara:<\/strong>
Bucure\u0219ti, Spitalul Clinic de Boli Infec\u021bioase \u0219i Tropicale Dr. Victor Babe\u0219 Laboratorul de
Imunologie, din 1981 p\u00e2na in prezent \u2014 Conducator Laborator Imunologie
Lucrari \u0219tiin\u021bifice publicate:<\/strong>
-un numar de 100 de comunic\u0103ri \u0219i articole dintre care 25 articole publicate \u00een reviste de specialitate de circula\u021bie interna\u021bional\u0103, indexate
monografii: \u201dSarcomul Kaposi\u201d Editura Tehnic\u0103, 1998, 230 pagini, unic autor \u201dApoptoza-Moartea celular\u0103 programat\u0103\u201d Ed. Academiei, 1999, 410 pagini, coautor Reac\u021bii alergice la medicamente\u201d Ed. Medical\u0103, 2002, 400 pagini, prim autor \u201dPatologia molecular\u0103 a pielii\u201d Ed. Medical\u0103, 2006, 495 pagini, unic autor \u201dDermato-Venerologie\u201d Ed. Didactic\u0103 \u0219i Pedagogic\u0103 2010, 300 pagini<\/p>\n<\/span><\/p>\n
Tel.: 0332.40.88.00-05<\/span>
E-mail: inscrieri@primaderma.ro<\/a>
<\/span>Website:\u00a0<\/span>www.eventernet.ro<\/a><\/p>\n