<\/span><\/strong><\/h4>\n<\/span><\/strong><\/h4>\nConf. Univ. Dr. Onofrei Viviana<\/span><\/strong>
\nUniversitatea de Medicin\u0103 \u0219i Farmacie \u201dGrigore T. Popa\u201d, Ia\u0219i
\nSpitalul Jude\u021bean Clinic de Urgen\u021be, Sec\u021bia Cardiologie, Ia\u0219i, Rom\u00e2nia<\/span><\/strong><\/h4>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”3.25″][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.7″ hover_enabled=”0″ sticky_enabled=”0″]<\/p>\n
Actualit\u0103\u021bi \u00een diagnosticul \u0219i strategiile terapeutice la pacien\u021bii cu sindrom posttrombotic<\/span>
Autor: Viviana Onofrei<\/span><\/p>\nCuvinte cheie: sindrom posttrombotic, tratament conservator, tratament invaziv<\/p>\n
Introducere: Sindromul posttrombotic (SPT) este o complica\u021bie frecvent\u0103 \u0219i invalidant\u0103 a trombozei venoase profunde (TVP), care reduce calitatea vie\u021bii \u0219i este costisitoare. SPT apare chiar \u0219i dup\u0103 tratamentul adecvat al TVP.
Materiale \u0219i metod\u0103: Pornind de la revizuirea sistematic\u0103 a literaturii recente, subiectul se axeaz\u0103 pe factorii de risc pentru SPT \u0219i noile metode disponibile de preven\u021bie \u0219i tratament.
Rezultate: Manifest\u0103rile clinice ale SPT sunt variate \u0219i diferite ca severitate. Obstruc\u021bia venoas\u0103 cronic\u0103 \u0219i refluxul valvular sunt principalele mecanisme care contribuie la apari\u021bia hipertensiunii venoase. Inflama\u021bia \u0219i predispozi\u021bia genetic\u0103 au de asemnea rol \u00een apari\u021bia \u0219i dezvoltarea SPT. Riscul absolut individual de apari\u021bie a SPT este dificil de estimat, dar date recente furnizeaz\u0103 informa\u021bii noi \u00een acest sens. \u00cen timp ce terapiile de compresie sunt esen\u021biale, eficien\u021ba drogurilor venoactive este incert\u0103. Tratamentul anticoagulant dizolv\u0103 frecvent trombusul par\u021bial. O serie de tehnici invazive, ca reconstruc\u021bia chirurgical\u0103, procedee hibride \u0219i recanalizarea endovascular\u0103 sunt disponibile actual. Utilizarea adecvat\u0103 a acestor tehnici noi la pacien\u021bi selec\u021biona\u021bi are poten\u021bialul de a reduce manifest\u0103rile SPT.
Concluzii: Exist\u0103 multe necunoscute \u00een managementul SPT. Este nevoie de studii viitoare pentru \u00een\u021belegerea fiziopatologiei, dezvoltarea de noi \u021binte terapeutice, c\u00e2t \u0219i afirmarea eficien\u021bei, siguran\u021bei \u0219i beneficiului cost-eficien\u021b\u0103 a diferitelor strategii. Prima linnie de tratament r\u0103m\u00e2ne cea conservatoare. \u00cen cazul SPT rezistent la tratament, \u00eenso\u021bit de sc\u0103derea calit\u0103\u021bii vie\u021bii, se va decide individual posibilitatea terapiei invazive. <\/p>\n
Update on diagnosis and treatment strategies in patients with post-thrombotic syndrome
<\/span>
Author: Viviana Onofrei<\/span><\/p>\nKeywords: post-thrombotic syndrome, conservative therapy, invasive treatment<\/p>\n
Introduction: The post-thrombotic syndrome (PTS) is a frequent, disabling complication of deep vein thrombosis (DVT) that reduces quality of life and is costly. PTS develops even when appropriate therapy is used to treat the DVT.
Material and method: Based on the systematic review of recent literature the topic focuses on risk factors for PTS and the available new methods to prevent and treat it.
Results: The clinical manifestations of PTS can be present in various combinations and severity. Persistent venous obstruction and valvular reflux are the main mechanisms contributing to venous hypertension. Inflammation and the genetic predisposition also play a role in promoting the development of PTS. The individual absolute risk of PTS is difficult to be predicted, but recent research provides new information. While compression-based therapies are essential to manage PTS, the effectiveness of venoactive drugs is uncertain. The anticoagulant therapy frequently ensures only partial clearance of thrombus. Some invasive procedures are also available, such as open surgical reconstructions, hybrid procedures, and endovenous recanalization. Treating appropriately selected patients with PTS the new strategies may have potential to decrease post-thrombotic manifestations.
Conclusions: There are many gaps in the management of PTS. Future studies are needed to understand the pathophysiology, to suggest future therapeutic targets as well as the effectiveness, safety, and cost-effectiveness of various strategies. First-line treatment should be conservative therapy. In case of therapy-resistant PTS with poor quality of life, the possibility of an invasive treatment should be made individually. <\/p>\n
Scurt CV<\/span><\/p>\nAbsolvent\u0103 a Facult\u0103\u0163ii de Medicin\u0103 \u015fi Farmacie \u201dGrigore T. Popa\u201d Ia\u015fi, promo\u021bia 1991<\/p>\n
Experien\u0163a profesional\u0103:<\/strong>
Conferen\u021biar universitar, Disciplina Medicin\u0103 Intern\u0103 (Cardiologie), Facultatea de Medicin\u0103, U.M.F. \u201cGrigore T. Popa\u201d Ia\u0219i
Activitate didactic\u0103 curicular\u0103 \u0219i extracuricular\u0103 continu\u0103 din 1996
Medic primar cardiologie \u0219i medicin\u0103 intern\u0103 la Clinica de Cardiologie, USTACC, Spitalul Jude\u021bean Clinic de Urgen\u021be \u201cSf. Spiridon\u201d Ia\u0219i
Doctor \u00een \u0219tiin\u021be medicale, teza de doctorat \u201dDisfunc\u021bia endotelial\u0103 \u00een hipertensiunea arterial\u0103\u201d, 2006
Competen\u021be \u00een Ecocardiografie General\u0103 \u0219i Ultrasonografie General\u0103
Masterat “Bazele nutri\u0163iei clinice”, 2011<\/p>\nApartenen\u0163a la Societ\u0103\u0163i \u015ftiin\u0163ifice:<\/strong>
Membr\u0103 \u00een Societatea Rom\u00e2n\u0103 de Cardiologie
Membr\u0103 \u00een Societatea European\u0103 de Cardiologie
Membr\u0103 \u00een Societatea European\u0103 de Hipertensiune
Membr\u0103 \u00een American Heart Association\/American College of Cardiology)<\/p>\nDistinc\u021bii:<\/strong>
European Hypertension Specialist
Diplom\u0103 de excelen\u021b\u0103 din partea Societ\u0103\u021bii Rom\u00e2ne de Hipertensiune
Fellow of European Society of Cardiology<\/p>\nDomenii de interes \u015ftiin\u0163ific:<\/strong>
Afectarea cardiovascular\u0103 \u00een patologia medical\u0103, hipertensiunea arterial\u0103, disfunc\u0163ia endotelial\u0103 \u015fi rigiditatea arterial\u0103, insuficien\u0163a cardiac\u0103, bolile vasculare, boli metabolice.
Implicare activ\u0103 \u00een activitatea de cercetare \u0219tiin\u021bific\u0103 (granturi de cercetare \u0219tiin\u021bific\u0103, coinvestigator \u00een studii clinice multicentrice interna\u021bionale, colaborator \u00een registre na\u021bionale \u0219i europene de specialitate)
Metode de investiga\u0163ie sau tratament originale introduse \u00een premier\u0103 na\u021bional\u0103 (studiul comparativ \u015fi integrat al disfunc\u0163iei endoteliale \u00een hipertensiunea arterial\u0103 prin metoda Complior \u015fi ecografie vascular\u0103 (2001), tromboliza ghidat\u0103 pe cateter \u00een trombozele venoase profunde (echipa Prof. Dr. Datcu \u2013 2004)
Editor de c\u0103r\u021bi de specialitate cu colectiv na\u021bional, manuale, peste 100 lucr\u0103ri \u0219tiin\u021bifice \u00een reviste ISI \u0219i BDI<\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22″ background_color=”rgba(117,194,33,0.23)” background_image=”https:\/\/pdi.ro\/2021\/wp-content\/uploads\/2020\/02\/back_justflowers_overlay1.png” background_blend=”luminosity” custom_padding=”54px|0px|0|0px|false|false” top_divider_style=”waves2″ top_divider_color=”#ffffff” top_divider_height=”155px” top_divider_height_tablet=”” top_divider_height_phone=”97px” top_divider_height_last_edited=”on|desktop” bottom_divider_style=”waves2″ bottom_divider_color=”#75c221″ bottom_divider_flip=”vertical” bottom_divider_height_tablet=”” bottom_divider_height_phone=”59px” bottom_divider_height_last_edited=”on|desktop”][et_pb_row column_structure=”3_5,2_5″ _builder_version=”3.25″ custom_padding=”61px|0px|69px|0px|false|false”][et_pb_column type=”3_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.4″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” text_line_height=”1.2em” header_font=”||||||||” background_layout=”dark” text_font_size_tablet=”” text_font_size_phone=”” text_font_size_last_edited=”on|desktop”]<\/p>\n
Contacteaz\u0103 operatorul PDI 2021<\/p>\n
[\/et_pb_text][et_pb_contact_form email=”contact@pdi.ro\/2021\/2019″ submit_button_text=”Trimite mesajul” _builder_version=”3.19.4″ title_font=”||||||||”][et_pb_contact_field field_id=”Name” field_title=”Nume” _builder_version=”3.18.9″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Email” field_title=”Adresa de e-mail” field_type=”email” _builder_version=”3.19.4″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Message” field_title=”Mesajul dvs.” field_type=”text” fullwidth_field=”on” _builder_version=”3.18.9″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][\/et_pb_contact_form][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.4″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark”]<\/p>\n
Operatorul PDI 2021<\/p>\n
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![\"\"](\"https:\/\/pdi.ro\/2021\/wp-content\/uploads\/2020\/02\/eventer_logo_150px.png\")
<\/span><\/p>\n<\/span><\/p>\n<\/span><\/p>\nAdresa: Str. A. Panu nr. 13, Iasi<\/span>
Tel.: 0332.40.88.00-05<\/span>
E-mail: inscrieri@primaderma.ro<\/a>
<\/span>Website:\u00a0<\/span>www.eventernet.ro<\/a><\/p>\n[\/et_pb_text][et_pb_text disabled_on=”off|off|off” _builder_version=”4.0.11″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” locked=”off”]<\/p>\n
Parteneri Media<\/p>\n
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Conf. Univ. Dr. Onofrei Viviana Universitatea de Medicin\u0103 \u0219i Farmacie \u201dGrigore T. Popa\u201d, Ia\u0219i Spitalul Jude\u021bean Clinic de Urgen\u021be, Sec\u021bia Cardiologie, Ia\u0219i, Rom\u00e2niaActualit\u0103\u021bi \u00een diagnosticul \u0219i strategiile terapeutice la pacien\u021bii cu sindrom posttromboticAutor: Viviana Onofrei Cuvinte cheie: sindrom posttrombotic, tratament conservator, tratament invaziv Introducere: Sindromul posttrombotic (SPT) este o complica\u021bie frecvent\u0103 \u0219i invalidant\u0103 a trombozei […]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-8086","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/8086","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/comments?post=8086"}],"version-history":[{"count":8,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/8086\/revisions"}],"predecessor-version":[{"id":9917,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/8086\/revisions\/9917"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/media?parent=8086"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Conf. Univ. Dr. Onofrei Viviana<\/span><\/strong>
\nUniversitatea de Medicin\u0103 \u0219i Farmacie \u201dGrigore T. Popa\u201d, Ia\u0219i
\nSpitalul Jude\u021bean Clinic de Urgen\u021be, Sec\u021bia Cardiologie, Ia\u0219i, Rom\u00e2nia<\/span><\/strong><\/h4>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”3.25″][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.7″ hover_enabled=”0″ sticky_enabled=”0″]<\/p>\n
Actualit\u0103\u021bi \u00een diagnosticul \u0219i strategiile terapeutice la pacien\u021bii cu sindrom posttrombotic<\/span>
Autor: Viviana Onofrei<\/span><\/p>\nCuvinte cheie: sindrom posttrombotic, tratament conservator, tratament invaziv<\/p>\n
Introducere: Sindromul posttrombotic (SPT) este o complica\u021bie frecvent\u0103 \u0219i invalidant\u0103 a trombozei venoase profunde (TVP), care reduce calitatea vie\u021bii \u0219i este costisitoare. SPT apare chiar \u0219i dup\u0103 tratamentul adecvat al TVP.
Materiale \u0219i metod\u0103: Pornind de la revizuirea sistematic\u0103 a literaturii recente, subiectul se axeaz\u0103 pe factorii de risc pentru SPT \u0219i noile metode disponibile de preven\u021bie \u0219i tratament.
Rezultate: Manifest\u0103rile clinice ale SPT sunt variate \u0219i diferite ca severitate. Obstruc\u021bia venoas\u0103 cronic\u0103 \u0219i refluxul valvular sunt principalele mecanisme care contribuie la apari\u021bia hipertensiunii venoase. Inflama\u021bia \u0219i predispozi\u021bia genetic\u0103 au de asemnea rol \u00een apari\u021bia \u0219i dezvoltarea SPT. Riscul absolut individual de apari\u021bie a SPT este dificil de estimat, dar date recente furnizeaz\u0103 informa\u021bii noi \u00een acest sens. \u00cen timp ce terapiile de compresie sunt esen\u021biale, eficien\u021ba drogurilor venoactive este incert\u0103. Tratamentul anticoagulant dizolv\u0103 frecvent trombusul par\u021bial. O serie de tehnici invazive, ca reconstruc\u021bia chirurgical\u0103, procedee hibride \u0219i recanalizarea endovascular\u0103 sunt disponibile actual. Utilizarea adecvat\u0103 a acestor tehnici noi la pacien\u021bi selec\u021biona\u021bi are poten\u021bialul de a reduce manifest\u0103rile SPT.
Concluzii: Exist\u0103 multe necunoscute \u00een managementul SPT. Este nevoie de studii viitoare pentru \u00een\u021belegerea fiziopatologiei, dezvoltarea de noi \u021binte terapeutice, c\u00e2t \u0219i afirmarea eficien\u021bei, siguran\u021bei \u0219i beneficiului cost-eficien\u021b\u0103 a diferitelor strategii. Prima linnie de tratament r\u0103m\u00e2ne cea conservatoare. \u00cen cazul SPT rezistent la tratament, \u00eenso\u021bit de sc\u0103derea calit\u0103\u021bii vie\u021bii, se va decide individual posibilitatea terapiei invazive. <\/p>\n
Update on diagnosis and treatment strategies in patients with post-thrombotic syndrome
<\/span>
Author: Viviana Onofrei<\/span><\/p>\nKeywords: post-thrombotic syndrome, conservative therapy, invasive treatment<\/p>\n
Introduction: The post-thrombotic syndrome (PTS) is a frequent, disabling complication of deep vein thrombosis (DVT) that reduces quality of life and is costly. PTS develops even when appropriate therapy is used to treat the DVT.
Material and method: Based on the systematic review of recent literature the topic focuses on risk factors for PTS and the available new methods to prevent and treat it.
Results: The clinical manifestations of PTS can be present in various combinations and severity. Persistent venous obstruction and valvular reflux are the main mechanisms contributing to venous hypertension. Inflammation and the genetic predisposition also play a role in promoting the development of PTS. The individual absolute risk of PTS is difficult to be predicted, but recent research provides new information. While compression-based therapies are essential to manage PTS, the effectiveness of venoactive drugs is uncertain. The anticoagulant therapy frequently ensures only partial clearance of thrombus. Some invasive procedures are also available, such as open surgical reconstructions, hybrid procedures, and endovenous recanalization. Treating appropriately selected patients with PTS the new strategies may have potential to decrease post-thrombotic manifestations.
Conclusions: There are many gaps in the management of PTS. Future studies are needed to understand the pathophysiology, to suggest future therapeutic targets as well as the effectiveness, safety, and cost-effectiveness of various strategies. First-line treatment should be conservative therapy. In case of therapy-resistant PTS with poor quality of life, the possibility of an invasive treatment should be made individually. <\/p>\n
Scurt CV<\/span><\/p>\nAbsolvent\u0103 a Facult\u0103\u0163ii de Medicin\u0103 \u015fi Farmacie \u201dGrigore T. Popa\u201d Ia\u015fi, promo\u021bia 1991<\/p>\n
Experien\u0163a profesional\u0103:<\/strong>
Conferen\u021biar universitar, Disciplina Medicin\u0103 Intern\u0103 (Cardiologie), Facultatea de Medicin\u0103, U.M.F. \u201cGrigore T. Popa\u201d Ia\u0219i
Activitate didactic\u0103 curicular\u0103 \u0219i extracuricular\u0103 continu\u0103 din 1996
Medic primar cardiologie \u0219i medicin\u0103 intern\u0103 la Clinica de Cardiologie, USTACC, Spitalul Jude\u021bean Clinic de Urgen\u021be \u201cSf. Spiridon\u201d Ia\u0219i
Doctor \u00een \u0219tiin\u021be medicale, teza de doctorat \u201dDisfunc\u021bia endotelial\u0103 \u00een hipertensiunea arterial\u0103\u201d, 2006
Competen\u021be \u00een Ecocardiografie General\u0103 \u0219i Ultrasonografie General\u0103
Masterat “Bazele nutri\u0163iei clinice”, 2011<\/p>\nApartenen\u0163a la Societ\u0103\u0163i \u015ftiin\u0163ifice:<\/strong>
Membr\u0103 \u00een Societatea Rom\u00e2n\u0103 de Cardiologie
Membr\u0103 \u00een Societatea European\u0103 de Cardiologie
Membr\u0103 \u00een Societatea European\u0103 de Hipertensiune
Membr\u0103 \u00een American Heart Association\/American College of Cardiology)<\/p>\nDistinc\u021bii:<\/strong>
European Hypertension Specialist
Diplom\u0103 de excelen\u021b\u0103 din partea Societ\u0103\u021bii Rom\u00e2ne de Hipertensiune
Fellow of European Society of Cardiology<\/p>\nDomenii de interes \u015ftiin\u0163ific:<\/strong>
Afectarea cardiovascular\u0103 \u00een patologia medical\u0103, hipertensiunea arterial\u0103, disfunc\u0163ia endotelial\u0103 \u015fi rigiditatea arterial\u0103, insuficien\u0163a cardiac\u0103, bolile vasculare, boli metabolice.
Implicare activ\u0103 \u00een activitatea de cercetare \u0219tiin\u021bific\u0103 (granturi de cercetare \u0219tiin\u021bific\u0103, coinvestigator \u00een studii clinice multicentrice interna\u021bionale, colaborator \u00een registre na\u021bionale \u0219i europene de specialitate)
Metode de investiga\u0163ie sau tratament originale introduse \u00een premier\u0103 na\u021bional\u0103 (studiul comparativ \u015fi integrat al disfunc\u0163iei endoteliale \u00een hipertensiunea arterial\u0103 prin metoda Complior \u015fi ecografie vascular\u0103 (2001), tromboliza ghidat\u0103 pe cateter \u00een trombozele venoase profunde (echipa Prof. Dr. Datcu \u2013 2004)
Editor de c\u0103r\u021bi de specialitate cu colectiv na\u021bional, manuale, peste 100 lucr\u0103ri \u0219tiin\u021bifice \u00een reviste ISI \u0219i BDI<\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22″ background_color=”rgba(117,194,33,0.23)” background_image=”https:\/\/pdi.ro\/2021\/wp-content\/uploads\/2020\/02\/back_justflowers_overlay1.png” background_blend=”luminosity” custom_padding=”54px|0px|0|0px|false|false” top_divider_style=”waves2″ top_divider_color=”#ffffff” top_divider_height=”155px” top_divider_height_tablet=”” top_divider_height_phone=”97px” top_divider_height_last_edited=”on|desktop” bottom_divider_style=”waves2″ bottom_divider_color=”#75c221″ bottom_divider_flip=”vertical” bottom_divider_height_tablet=”” bottom_divider_height_phone=”59px” bottom_divider_height_last_edited=”on|desktop”][et_pb_row column_structure=”3_5,2_5″ _builder_version=”3.25″ custom_padding=”61px|0px|69px|0px|false|false”][et_pb_column type=”3_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.4″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” text_line_height=”1.2em” header_font=”||||||||” background_layout=”dark” text_font_size_tablet=”” text_font_size_phone=”” text_font_size_last_edited=”on|desktop”]<\/p>\n
Contacteaz\u0103 operatorul PDI 2021<\/p>\n
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Operatorul PDI 2021<\/p>\n
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<\/span><\/p>\n<\/span><\/p>\n<\/span><\/p>\nAdresa: Str. A. Panu nr. 13, Iasi<\/span>
Tel.: 0332.40.88.00-05<\/span>
E-mail: inscrieri@primaderma.ro<\/a>
<\/span>Website:\u00a0<\/span>www.eventernet.ro<\/a><\/p>\n[\/et_pb_text][et_pb_text disabled_on=”off|off|off” _builder_version=”4.0.11″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” locked=”off”]<\/p>\n
Parteneri Media<\/p>\n
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Conf. Univ. Dr. Onofrei Viviana Universitatea de Medicin\u0103 \u0219i Farmacie \u201dGrigore T. Popa\u201d, Ia\u0219i Spitalul Jude\u021bean Clinic de Urgen\u021be, Sec\u021bia Cardiologie, Ia\u0219i, Rom\u00e2niaActualit\u0103\u021bi \u00een diagnosticul \u0219i strategiile terapeutice la pacien\u021bii cu sindrom posttromboticAutor: Viviana Onofrei Cuvinte cheie: sindrom posttrombotic, tratament conservator, tratament invaziv Introducere: Sindromul posttrombotic (SPT) este o complica\u021bie frecvent\u0103 \u0219i invalidant\u0103 a trombozei […]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-8086","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/8086","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/comments?post=8086"}],"version-history":[{"count":8,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/8086\/revisions"}],"predecessor-version":[{"id":9917,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/8086\/revisions\/9917"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/media?parent=8086"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Autor: Viviana Onofrei<\/span><\/p>\n
Cuvinte cheie: sindrom posttrombotic, tratament conservator, tratament invaziv<\/p>\n
Introducere: Sindromul posttrombotic (SPT) este o complica\u021bie frecvent\u0103 \u0219i invalidant\u0103 a trombozei venoase profunde (TVP), care reduce calitatea vie\u021bii \u0219i este costisitoare. SPT apare chiar \u0219i dup\u0103 tratamentul adecvat al TVP.
Materiale \u0219i metod\u0103: Pornind de la revizuirea sistematic\u0103 a literaturii recente, subiectul se axeaz\u0103 pe factorii de risc pentru SPT \u0219i noile metode disponibile de preven\u021bie \u0219i tratament.
Rezultate: Manifest\u0103rile clinice ale SPT sunt variate \u0219i diferite ca severitate. Obstruc\u021bia venoas\u0103 cronic\u0103 \u0219i refluxul valvular sunt principalele mecanisme care contribuie la apari\u021bia hipertensiunii venoase. Inflama\u021bia \u0219i predispozi\u021bia genetic\u0103 au de asemnea rol \u00een apari\u021bia \u0219i dezvoltarea SPT. Riscul absolut individual de apari\u021bie a SPT este dificil de estimat, dar date recente furnizeaz\u0103 informa\u021bii noi \u00een acest sens. \u00cen timp ce terapiile de compresie sunt esen\u021biale, eficien\u021ba drogurilor venoactive este incert\u0103. Tratamentul anticoagulant dizolv\u0103 frecvent trombusul par\u021bial. O serie de tehnici invazive, ca reconstruc\u021bia chirurgical\u0103, procedee hibride \u0219i recanalizarea endovascular\u0103 sunt disponibile actual. Utilizarea adecvat\u0103 a acestor tehnici noi la pacien\u021bi selec\u021biona\u021bi are poten\u021bialul de a reduce manifest\u0103rile SPT.
Concluzii: Exist\u0103 multe necunoscute \u00een managementul SPT. Este nevoie de studii viitoare pentru \u00een\u021belegerea fiziopatologiei, dezvoltarea de noi \u021binte terapeutice, c\u00e2t \u0219i afirmarea eficien\u021bei, siguran\u021bei \u0219i beneficiului cost-eficien\u021b\u0103 a diferitelor strategii. Prima linnie de tratament r\u0103m\u00e2ne cea conservatoare. \u00cen cazul SPT rezistent la tratament, \u00eenso\u021bit de sc\u0103derea calit\u0103\u021bii vie\u021bii, se va decide individual posibilitatea terapiei invazive. <\/p>\n
Update on diagnosis and treatment strategies in patients with post-thrombotic syndrome Keywords: post-thrombotic syndrome, conservative therapy, invasive treatment<\/p>\n Introduction: The post-thrombotic syndrome (PTS) is a frequent, disabling complication of deep vein thrombosis (DVT) that reduces quality of life and is costly. PTS develops even when appropriate therapy is used to treat the DVT. Scurt CV<\/span><\/p>\n Absolvent\u0103 a Facult\u0103\u0163ii de Medicin\u0103 \u015fi Farmacie \u201dGrigore T. Popa\u201d Ia\u015fi, promo\u021bia 1991<\/p>\n Experien\u0163a profesional\u0103:<\/strong> Apartenen\u0163a la Societ\u0103\u0163i \u015ftiin\u0163ifice:<\/strong> Distinc\u021bii:<\/strong> Domenii de interes \u015ftiin\u0163ific:<\/strong> [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22″ background_color=”rgba(117,194,33,0.23)” background_image=”https:\/\/pdi.ro\/2021\/wp-content\/uploads\/2020\/02\/back_justflowers_overlay1.png” background_blend=”luminosity” custom_padding=”54px|0px|0|0px|false|false” top_divider_style=”waves2″ top_divider_color=”#ffffff” top_divider_height=”155px” top_divider_height_tablet=”” top_divider_height_phone=”97px” top_divider_height_last_edited=”on|desktop” bottom_divider_style=”waves2″ bottom_divider_color=”#75c221″ bottom_divider_flip=”vertical” bottom_divider_height_tablet=”” bottom_divider_height_phone=”59px” bottom_divider_height_last_edited=”on|desktop”][et_pb_row column_structure=”3_5,2_5″ _builder_version=”3.25″ custom_padding=”61px|0px|69px|0px|false|false”][et_pb_column type=”3_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.4″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” text_line_height=”1.2em” header_font=”||||||||” background_layout=”dark” text_font_size_tablet=”” text_font_size_phone=”” text_font_size_last_edited=”on|desktop”]<\/p>\n Contacteaz\u0103 operatorul PDI 2021<\/p>\n [\/et_pb_text][et_pb_contact_form email=”contact@pdi.ro\/2021\/2019″ submit_button_text=”Trimite mesajul” _builder_version=”3.19.4″ title_font=”||||||||”][et_pb_contact_field field_id=”Name” field_title=”Nume” _builder_version=”3.18.9″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” 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_builder_version=”4.9.4″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark”]<\/p>\n Operatorul PDI 2021<\/p>\n [\/et_pb_text][et_pb_text _builder_version=”4.0.11″ text_font=”||||||||”]<\/p>\n <\/span><\/p>\n <\/span><\/p>\n Adresa: Str. A. Panu nr. 13, Iasi<\/span> [\/et_pb_text][et_pb_text disabled_on=”off|off|off” _builder_version=”4.0.11″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” locked=”off”]<\/p>\n Parteneri Media<\/p>\n [\/et_pb_text][et_pb_gallery gallery_ids=”7203,7204,7232,7231″ fullwidth=”on” _builder_version=”4.0.11″ transform_scale=”86%|86%” max_width=”63%” auto=”on” auto_speed=”3500″ hover_transition_duration=”100ms” hover_transition_delay=”50ms” hover_transition_speed_curve=”ease-in-out” locked=”off”][\/et_pb_gallery][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" Conf. Univ. Dr. Onofrei Viviana Universitatea de Medicin\u0103 \u0219i Farmacie \u201dGrigore T. Popa\u201d, Ia\u0219i Spitalul Jude\u021bean Clinic de Urgen\u021be, Sec\u021bia Cardiologie, Ia\u0219i, Rom\u00e2niaActualit\u0103\u021bi \u00een diagnosticul \u0219i strategiile terapeutice la pacien\u021bii cu sindrom posttromboticAutor: Viviana Onofrei Cuvinte cheie: sindrom posttrombotic, tratament conservator, tratament invaziv Introducere: Sindromul posttrombotic (SPT) este o complica\u021bie frecvent\u0103 \u0219i invalidant\u0103 a trombozei […]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-8086","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/8086","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/comments?post=8086"}],"version-history":[{"count":8,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/8086\/revisions"}],"predecessor-version":[{"id":9917,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/8086\/revisions\/9917"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/media?parent=8086"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
<\/span>
Author: Viviana Onofrei<\/span><\/p>\n
Material and method: Based on the systematic review of recent literature the topic focuses on risk factors for PTS and the available new methods to prevent and treat it.
Results: The clinical manifestations of PTS can be present in various combinations and severity. Persistent venous obstruction and valvular reflux are the main mechanisms contributing to venous hypertension. Inflammation and the genetic predisposition also play a role in promoting the development of PTS. The individual absolute risk of PTS is difficult to be predicted, but recent research provides new information. While compression-based therapies are essential to manage PTS, the effectiveness of venoactive drugs is uncertain. The anticoagulant therapy frequently ensures only partial clearance of thrombus. Some invasive procedures are also available, such as open surgical reconstructions, hybrid procedures, and endovenous recanalization. Treating appropriately selected patients with PTS the new strategies may have potential to decrease post-thrombotic manifestations.
Conclusions: There are many gaps in the management of PTS. Future studies are needed to understand the pathophysiology, to suggest future therapeutic targets as well as the effectiveness, safety, and cost-effectiveness of various strategies. First-line treatment should be conservative therapy. In case of therapy-resistant PTS with poor quality of life, the possibility of an invasive treatment should be made individually. <\/p>\n
Conferen\u021biar universitar, Disciplina Medicin\u0103 Intern\u0103 (Cardiologie), Facultatea de Medicin\u0103, U.M.F. \u201cGrigore T. Popa\u201d Ia\u0219i
Activitate didactic\u0103 curicular\u0103 \u0219i extracuricular\u0103 continu\u0103 din 1996
Medic primar cardiologie \u0219i medicin\u0103 intern\u0103 la Clinica de Cardiologie, USTACC, Spitalul Jude\u021bean Clinic de Urgen\u021be \u201cSf. Spiridon\u201d Ia\u0219i
Doctor \u00een \u0219tiin\u021be medicale, teza de doctorat \u201dDisfunc\u021bia endotelial\u0103 \u00een hipertensiunea arterial\u0103\u201d, 2006
Competen\u021be \u00een Ecocardiografie General\u0103 \u0219i Ultrasonografie General\u0103
Masterat “Bazele nutri\u0163iei clinice”, 2011<\/p>\n
Membr\u0103 \u00een Societatea Rom\u00e2n\u0103 de Cardiologie
Membr\u0103 \u00een Societatea European\u0103 de Cardiologie
Membr\u0103 \u00een Societatea European\u0103 de Hipertensiune
Membr\u0103 \u00een American Heart Association\/American College of Cardiology)<\/p>\n
European Hypertension Specialist
Diplom\u0103 de excelen\u021b\u0103 din partea Societ\u0103\u021bii Rom\u00e2ne de Hipertensiune
Fellow of European Society of Cardiology<\/p>\n
Afectarea cardiovascular\u0103 \u00een patologia medical\u0103, hipertensiunea arterial\u0103, disfunc\u0163ia endotelial\u0103 \u015fi rigiditatea arterial\u0103, insuficien\u0163a cardiac\u0103, bolile vasculare, boli metabolice.
Implicare activ\u0103 \u00een activitatea de cercetare \u0219tiin\u021bific\u0103 (granturi de cercetare \u0219tiin\u021bific\u0103, coinvestigator \u00een studii clinice multicentrice interna\u021bionale, colaborator \u00een registre na\u021bionale \u0219i europene de specialitate)
Metode de investiga\u0163ie sau tratament originale introduse \u00een premier\u0103 na\u021bional\u0103 (studiul comparativ \u015fi integrat al disfunc\u0163iei endoteliale \u00een hipertensiunea arterial\u0103 prin metoda Complior \u015fi ecografie vascular\u0103 (2001), tromboliza ghidat\u0103 pe cateter \u00een trombozele venoase profunde (echipa Prof. Dr. Datcu \u2013 2004)
Editor de c\u0103r\u021bi de specialitate cu colectiv na\u021bional, manuale, peste 100 lucr\u0103ri \u0219tiin\u021bifice \u00een reviste ISI \u0219i BDI<\/p>\n<\/span><\/p>\n
Tel.: 0332.40.88.00-05<\/span>
E-mail: inscrieri@primaderma.ro<\/a>
<\/span>Website:\u00a0<\/span>www.eventernet.ro<\/a><\/p>\n