{"id":9537,"date":"2021-06-25T14:50:54","date_gmt":"2021-06-25T12:50:54","guid":{"rendered":"https:\/\/primaderma.ro\/?page_id=9537"},"modified":"2021-06-25T14:50:54","modified_gmt":"2021-06-25T12:50:54","slug":"prof-dr-zipeto-donato","status":"publish","type":"page","link":"https:\/\/pdi.ro\/2021\/prof-dr-zipeto-donato\/","title":{"rendered":"Prof. Dr. Zipeto Donato"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; fullwidth=&#8221;on&#8221; disabled_on=&#8221;on|off|off&#8221; _builder_version=&#8221;3.22&#8243; custom_margin=&#8221;||&#8221; custom_padding=&#8221;15px||29px&#8221; top_divider_style=&#8221;waves2&#8243; top_divider_color=&#8221;#f0622a&#8221; top_divider_flip=&#8221;horizontal|vertical&#8221; bottom_divider_style=&#8221;waves2&#8243; bottom_divider_color=&#8221;#fcdedb&#8221; bottom_divider_height=&#8221;105px&#8221; bottom_divider_flip=&#8221;vertical&#8221; global_module=&#8221;9062&#8243; collapsed=&#8221;off&#8221;][et_pb_fullwidth_header title=&#8221;@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF90aXRsZSIsInNldHRpbmdzIjp7ImJlZm9yZSI6IiIsImFmdGVyIjoiIn19@&#8221; 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content_font_size_last_edited=&#8221;on|desktop&#8221;][\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.4.8&#8243;][et_pb_row column_structure=&#8221;2_5,3_5&#8243; _builder_version=&#8221;3.25&#8243; locked=&#8221;off&#8221;][et_pb_column type=&#8221;2_5&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_image src=&#8221;https:\/\/pdi.ro\/2021\/wp-content\/uploads\/2021\/06\/Zipeto-Donato_1.jpg&#8221; align=&#8221;center&#8221; align_tablet=&#8221;center&#8221; align_phone=&#8221;&#8221; align_last_edited=&#8221;on|desktop&#8221; _builder_version=&#8221;4.9.6&#8243; max_width=&#8221;25%&#8221; hover_enabled=&#8221;0&#8243; border_radii=&#8221;on|100px|100px|100px|100px&#8221; title_text=&#8221;Zipeto Donato_1&#8243; sticky_enabled=&#8221;0&#8243;][\/et_pb_image][\/et_pb_column][et_pb_column type=&#8221;3_5&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.9.6&#8243; hover_enabled=&#8221;0&#8243; sticky_enabled=&#8221;0&#8243;]<\/p>\n<h4><span style=\"color: #ff6600;\"><strong><\/strong><\/span><\/h4>\n<h4><span style=\"color: #ff6600;\"><strong><\/strong><\/span><\/h4>\n<h4><span style=\"color: #ff6600;\"><strong><\/strong><\/span><\/h4>\n<h4><span style=\"color: #ff6600;\"><strong>Prof. Dr. Zipeto Donato<\/strong><\/span><br \/>\n<span style=\"color: #ff6600;\"><strong>University of Verona, Italia<\/strong><\/span><\/h4>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;3.25&#8243; locked=&#8221;off&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.9.6&#8243; hover_enabled=&#8221;0&#8243; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p><span style=\"color: #ff6600;\">Response to vaccination in na\u00efve versus previously SARS-CoV-2 infected subjects<\/span><br \/><span style=\"color: #ff6600;\"> Autori: Luca Dalle Carbonare1, Maria Teresa Valenti1, Zeno Bisoffi2,3, Chiara Piubelli2, Massimo Pizzato4, Silvia Accordini4, Sara Mariotto5, Sergio Ferrari5, Arianna Minoia1, Jessica Bertacco1, Veronica Li Vigni1, Gianluigi Dorelli1, Ernesto Crisafulli1, Daniela Alberti5, Laura Masin5, Natalia Tiberti2, Silvia Stefania Longoni2, Lucia Lopalco6, Alberto Beretta7, DONATO ZIPETO5*<\/span><\/p>\n<p><span style=\"color: #000000;\">1Department of Medicine, University of Verona<\/span><br \/><span style=\"color: #000000;\">2Department of Infectious, Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar (Verona)<\/span><br \/><span style=\"color: #000000;\">3Department of Diagnostics and Public Health, University of Verona<\/span><br \/><span style=\"color: #000000;\">4Department of Cellular, Computational and Integrative Biology, University of Trento, Povo (Trento)<\/span><br \/><span style=\"color: #000000;\">5Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona<\/span><br \/><span style=\"color: #000000;\">6Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, Milan<\/span><br \/><span style=\"color: #000000;\">7Covi2 Technologies Srl, Novara<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">We profiled antibody responses in a cohort of recipients of the BTN162b2 mRNA vaccine who were either immunologically na\u00efve (n=50) or had been previously infected with SARS\u0002CoV-2 (n=51). Of the previously infected, 25 and 26 were infected during the first and second pandemic waves in Italy, respectively; the majority of those from the first wave had corresponding waning antibody titres with low to undetectable levels of anti-S antibodies and low anti-N antibodies. We observed in recipients who had been previously infected that spike-specific IgG and pseudovirus neutralization titres were rapidly recalled by a single vaccine dose to higher levels than those in na\u00efve recipients after the second vaccine dose, irrespective of waning antibody responses. In all recipients, a single vaccine dose was sufficient to induce a potent IgA response that was not associated with serum neutralization titres.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #ff6600;\">Scurt CV<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\"><em>A. Personal Statement:<\/em><br \/>My current specific areas of expertise include molecular biology and genome editing (CRISPR\/Cas9 technique) and<br \/>molecular virology. Current research interests are the analysis of the interactions between viral and cellular proteins, the<br \/>study of MHC-I variants related to HIV infection progression to AIDS, the study of the relationship between viral infections<br \/>and neurodegenerative diseases, and the study of the immunity against SARS-CoV-2.<br \/><em>B. Positions and Honors<\/em><br \/>Professional Experience:<br \/>Associate Professor in Molecular Biology, University of Verona (2014-current)<br \/>Assistant Professor in Molecular Biology, University of Verona (2002-2014)<br \/>Teaching duties: molecular biology, Basics of Molecular Virology and Gene Therapy, Pharmacogenomics, Human<br \/>Retroviruses, zoonosis and emerging viruses.<br \/><em>Main Grants and Awards:<\/em><br \/>Brain Research Foundation Verona, Project \u201cNeurotropism of SARS-CoV-2: virological, cellular, molecular and<br \/>pathogenetic aspects (2020).<br \/>Gilead Fellowship Program Grant, project \u201cHIV-associated neurocognitive disorders: a clinical, virological and<br \/>immunological approach to early definition of biomarkers\u201d (2019)<br \/>EUROPRISE Innovation Award, \u201cAnalysis of the interaction between HLA-C and HIV-1 Env\u201d, European Commission, 6th<br \/>FP (2011).<br \/>6th FP, \u201cEuropean Vaccines and Microbicides Enterprise\u201d. European Commission EUROPRISE Project (2007-2011)<br \/><em>International duties:<\/em><br \/>2014-2020: Expert evaluator, European Commission, REA, H2020-HSCA-IF, LIF Panel<br \/>2016-2017: Post-project evaluator, Baltinfect Project, Riga Stradina University, Riga (LV)<br \/>2014-2018: GHIT Fund Reviewer, Japanese R&amp;D for Global Health<br \/>2014: Expert evaluator, European Commission, H2020-PCH-2014-two-stage (01, 03, 17, 18, 22)<br \/>2010-2014: Expert evaluator, European Commission, REA, FP7-PEOPLE, Life Panel<br \/>2009: Evaluator NHLS Research Trust Grant<br \/><em>C. Editorial Activity<\/em><br \/>Guest Editor for the Journal of Immunology Research, Special Issue on \u201cInflammation in Cancer: Part of the problem or Part<br \/>of the Solution?\u201d, 2018 and 2020.<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.9.6&#8243; background_color=&#8221;rgba(117,194,33,0.23)&#8221; background_image=&#8221;https:\/\/pdi.ro\/2021\/wp-content\/uploads\/2021\/05\/PDI2021_header_1920x550px.jpg&#8221; background_blend=&#8221;multiply&#8221; custom_padding=&#8221;54px|0px|0|0px|false|false&#8221; top_divider_style=&#8221;waves2&#8243; top_divider_color=&#8221;#ffffff&#8221; top_divider_height=&#8221;155px&#8221; top_divider_height_tablet=&#8221;&#8221; top_divider_height_phone=&#8221;97px&#8221; top_divider_height_last_edited=&#8221;on|desktop&#8221; bottom_divider_style=&#8221;waves2&#8243; bottom_divider_color=&#8221;#75c221&#8243; bottom_divider_flip=&#8221;vertical&#8221; 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A. Panu nr. 13, Iasi<\/span><br \/> <span>Tel.: 0332.40.88.00-05<\/span><br \/> <span>E-mail: <a href=\"mailto:inscrieri@primaderma.ro\" target=\"_blank\" rel=\"noopener noreferrer\">inscrieri@primaderma.ro<\/a><br \/> <\/span><span>Website:\u00a0<\/span><a href=\"http:\/\/www.eventernet.ro\/\" target=\"Blank\" rel=\"noopener noreferrer\">www.eventernet.ro<\/a><\/p>\n<p>[\/et_pb_text][et_pb_text disabled_on=&#8221;off|off|off&#8221; _builder_version=&#8221;4.0.11&#8243; text_font=&#8221;Kaushan Script||||||||&#8221; text_text_color=&#8221;#f0622a&#8221; text_font_size=&#8221;30px&#8221; header_font=&#8221;||||||||&#8221; background_layout=&#8221;dark&#8221; locked=&#8221;off&#8221;]<\/p>\n<p>Parteneri Media<\/p>\n<p>[\/et_pb_text][et_pb_gallery gallery_ids=&#8221;7203,7204,9252,9464&#8243; fullwidth=&#8221;on&#8221; _builder_version=&#8221;4.9.6&#8243; transform_scale=&#8221;86%|86%&#8221; max_width=&#8221;63%&#8221; auto=&#8221;on&#8221; auto_speed=&#8221;3500&#8243; hover_transition_duration=&#8221;100ms&#8221; hover_transition_delay=&#8221;50ms&#8221; hover_transition_speed_curve=&#8221;ease-in-out&#8221; locked=&#8221;off&#8221;][\/et_pb_gallery][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Prof. Dr. Zipeto Donato University of Verona, ItaliaResponse to vaccination in na\u00efve versus previously SARS-CoV-2 infected subjects Autori: Luca Dalle Carbonare1, Maria Teresa Valenti1, Zeno Bisoffi2,3, Chiara Piubelli2, Massimo Pizzato4, Silvia Accordini4, Sara Mariotto5, Sergio Ferrari5, Arianna Minoia1, Jessica Bertacco1, Veronica Li Vigni1, Gianluigi Dorelli1, Ernesto Crisafulli1, Daniela Alberti5, Laura Masin5, Natalia Tiberti2, Silvia Stefania [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-9537","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/9537","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/comments?post=9537"}],"version-history":[{"count":3,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/9537\/revisions"}],"predecessor-version":[{"id":9541,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/9537\/revisions\/9541"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/media?parent=9537"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}