{"id":9596,"date":"2021-06-29T14:56:15","date_gmt":"2021-06-29T12:56:15","guid":{"rendered":"https:\/\/primaderma.ro\/?page_id=9596"},"modified":"2021-06-29T14:56:15","modified_gmt":"2021-06-29T12:56:15","slug":"prof-dr-calina-daniela","status":"publish","type":"page","link":"https:\/\/pdi.ro\/2021\/prof-dr-calina-daniela\/","title":{"rendered":"Prof. Dr. C\u0103lina Daniela"},"content":{"rendered":"

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Prof. Dr. C\u0103lina Daniela<\/strong><\/span>
\n Universitatea de Medicin\u0103 \u0219i Farmacie Craiova<\/strong><\/span><\/h4>\n

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Tratamentul acneei – de la empiricul fitoterapeutic la nanotehnologii<\/span>
Autori: Daniela C\u0103lina, Alice Elena Ghenea, Anca Oana Docea<\/span>
Universitatea de Medicin\u0103 \u015fi Farmacie din Craiova<\/p>\n

Acneea este \u00eent\u00e2lnit\u0103 \u00een r\u00e2ndul adolescen\u021bilor \u0219i adul\u021bilor iar efectele psihosociale sunt semnificative. De-a lungul timpului s-au \u00eencercat diverse terapii pornind de la utilizarea produselor botanice \u0219i fitochimice \u00een produsele dermatologice; la terapiile standard orale \u0219i topice dar cu efecte secundare semnificative cum ar fi iritarea, \u00eenro\u0219irea, peelingul pielii, tulbur\u0103ri gastro-intestinale \u0219i dezvoltarea bacteriilor rezistente la medicamente. \u020an ultimii ani s-au dezvoltat nanotehnologiile (nano: o miliardime) iar nanodermatologia s-a conturat ca o lumin\u0103 str\u0103lucitoare dincolo de acest orizont; noile tratamente cu nanoparticule in afec\u021biunile dermatologice, \u00een special acneea av\u00e2nd rezultate promi\u021b\u0103toare. Nanoparticulele 10 -1000 nm \u0219i au avantajul eliber\u0103rii la \u021bint\u0103 a substan\u021belor, eliberarea sus\u021binut\u0103, protejarea medicamentelor labile de degradare, toxicitate sc\u0103zut\u0103 \u0219i aderen\u021b\u0103 mare de tegumente. Nanotransportorii cu eliberare la \u021bint\u0103 sunt lipozomii, micelii, nanoparticule lipidice polimerice, nanocapsule, nanosfere cu aur sau argint, cubozomi, nanoparticule solide cu substan\u021be anorganice \u0219i emulsii sub-micrometrice. Dac\u0103 \u00een formul\u0103rile farmaceutice topice clasice, particulele de oxid de zinc sunt \u00een mod obi\u0219nuit opace \u0219i grase; \u00eencorporarea lor \u00een nanocarriers determin\u0103 un efect de vanishing \u015fi comfort pl\u0103cut la administrare. Emulsiile cu nanoparticule sunt mai pu\u021bin uleioase, au o textur\u0103 mai bun\u0103 \u0219i penetreaz\u0103 mai ad\u00e2nc pielea \u0219i p\u0103rul atunci c\u00e2nd sunt \u00eencorporate \u00een emolien\u021bi \u0219i balsamuri pentru p\u0103r. \u020an lumina acestor aspecte s-au dezvoltat formul\u0103ri topice antiacneice inovatoare cu nanoparticule \u00een care s-au \u00eencorporat: acid azelaic; adapalene sau adapalene-vitamina C; oxid nitric cu efect antibacterian; chitosan-alginat cu efecte antiinflamatorii \u0219i antibacteriene (anti Propionibacterium acnes); gluconat de clorhexidin\u0103, dioxid de Titan, argint cu efecte antiseptic.<\/span><\/p>\n

Acne treatment – from empirical phytotherapy to nanotechnologies<\/span>
Autori: Daniela Calina, Alice Elena Ghenea, Anca Oana Docea<\/span>
University of Medicine and Pharmacy of Craiova<\/p>\n

Acne is common in adolescents and adults and the psychosocial effects are significant. Over time, various therapies have been tried, starting with the use of botanical and phytochemical products in dermatological products; to standard oral and topical therapies but with significant side effects such as irritation, redness, skin peeling, gastrointestinal disorders and the development of drug-resistant bacteria. In recent years, nanotechnologies have developed (nano: one billionth) and nanodermatology has emerged as a bright light beyond this horizon; new nanoparticle treatments in dermatological diseases, especially acne with promising results. Nanoparticles 10 -1000 nm and have the advantage of targeted release of substances, sustained release, protection from labile drugs of degradation, low toxicity and high skin adhesion. Targeted nanotransporters are liposomes, mycelia, polymeric lipid nanoparticles, nanocapsules, gold or silver nanospheres, cubosomes, solid nanoparticles with inorganic substances and sub-micrometric emulsions. If in classical topical pharmaceutical formulations, the zinc oxide particles are usually opaque and greasy; their incorporation into nanocarriers determines a vanishing effect and a pleasant comfort when administered. Nanoparticle emulsions are less oily, have a better texture and penetrate deeper into the skin and hair when incorporated into emollients and hair conditioners. In light of these aspects, innovative topical anti-acne formulations with nanoparticles have been developed which have incorporated: azelaic acid; adapalene or adapalene-vitamin C; nitric oxide with antibacterial effect; chitosan-alginate with anti-inflammatory and antibacterial effects (anti Propionibacterium acnes); chlorhexidine gluconate, titanium dioxide, silver with antiseptic effects.<\/span><\/p>\n

Scurt CV<\/span><\/p>\n

Dr. Daniela C\u0103lina este absolvent\u0103 a facult\u0103\u021bii de Medicin\u0103 General\u0103 (1998), \u0219i a Facult\u0103\u021bii de Farmacie (2003), U.M.F. Craiova, doctor \u00een Farmacie (2006), farmacist primar \u00een specialitatea Farmacie clinic\u0103. Din 2018 este Profesor Universitar la diciplina Farmacie Clinic\u0103, Facultatea de Farmacie U.M.F. Craiova. Activit\u0103\u021bile de cercetare sunt din domeniul farmaciei clinice, farmacologiei \u0219i toxicologiei experimentale prin colabor\u0103ri multidisciplinare, dermatofarmacie \u0219i cosmetology. Este autor a peste 100 de lucr\u0103ri \u00een extenso publicate \u00een jurnale interna\u021bionale, mai mult de 85 \u00een jurnale indexate ISI (1659 cit\u0103ri- Iulie 2021, Hirsch Index 25). De asemenea este autor a patru capitole de c\u0103r\u021bi publicate \u00een edituri interna\u021bionale \u0219i 12 capitole\/c\u0103r\u021bi publicate \u00een edituri na\u021bionale; Editorial Board Member \u0219i Guest Associate Editor al unor jurnale din edituri interna\u021bionale de prestigiu (Frontiers, Elsevier, MDPI), reviewer pentru 52 de jurnale \u0219tiin\u021bifice din domeniul Medicinei \u0219i Farmaciei clinice. <\/span><\/p>\n

Membru \u00een diferite asocia\u021bii profesionale interna\u021bionale:
\u2022 International Pharmaceutical Federation (FIP)
\u2022 European Society of Clinical Microbiology and Infectious Diseases (ESCMID)
\u2022 European Asociation of Toxicology (EUROTOX)
\u2022 European Association of hospital pharmacists (EAHP)
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Contacteaz\u0103 operatorul PDI 2021<\/p>\n

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Operatorul PDI 2021<\/p>\n

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\"\"<\/span><\/p>\n

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Adresa: Str. A. Panu nr. 13, Iasi<\/span>
Tel.: 0332.40.88.00-05<\/span>
E-mail: inscrieri@primaderma.ro<\/a>
<\/span>Website:\u00a0<\/span>www.eventernet.ro<\/a><\/p>\n

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Parteneri Media<\/p>\n

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Prof. Dr. C\u0103lina Daniela Universitatea de Medicin\u0103 \u0219i Farmacie CraiovaTratamentul acneei – de la empiricul fitoterapeutic la nanotehnologii Autori: Daniela C\u0103lina, Alice Elena Ghenea, Anca Oana DoceaUniversitatea de Medicin\u0103 \u015fi Farmacie din Craiova Acneea este \u00eent\u00e2lnit\u0103 \u00een r\u00e2ndul adolescen\u021bilor \u0219i adul\u021bilor iar efectele psihosociale sunt semnificative. De-a lungul timpului s-au \u00eencercat diverse terapii pornind de […]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-9596","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/9596","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/comments?post=9596"}],"version-history":[{"count":3,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/9596\/revisions"}],"predecessor-version":[{"id":9600,"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/pages\/9596\/revisions\/9600"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2021\/wp-json\/wp\/v2\/media?parent=9596"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}