<\/span><\/strong><\/h4>\n<\/span><\/strong><\/h4>\n\u0218ef. Lucr. Dr.\u00a0Voiculescu Vlad<\/span><\/strong>
\n Universitatea de Medicin\u0103 \u015fi Farmacie “Carol Davila\u201d Bucure\u015fti, Rom\u00e2nia<\/span><\/strong><\/h4>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.16″ global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.17.0″ global_colors_info=”{}”]<\/p>\n
CSIESA: un nou scor pentru evaluarea \u00eemb\u0103tr\u00e2nirii cutanate intrinseci \u0219i extrinseci bazat pe microscopie confocal\u0103 de reflectan\u021b\u0103 in vivo<\/span>
Autori: V.M. Voiculescu1,2, A.M. Malciu2, L. Banciu2, E.C. Dobric\u01032, M. Lupu1,3<\/span>
1 Catedra de Dermatologie, Universitatea de Medicin\u0103 \u0219i Farmacie \u201eCarol Davila\u201d Bucure\u0219ti, Rom\u00e2nia
2 Clinica de Dermatologie Oncologic\u0103 \u0219i Imunologie Clinic\u0103, Spitalul Universitar de Urgen\u021b\u0103 Elias, Bucure\u0219ti, Rom\u00e2nia
3 Departamentul de Dermatologie, Centrul Medical Med-As, Bucure\u0219ti, Rom\u00e2nia<\/p>\nCuvinte cheie: microscopie confocal\u0103 de reflectan\u021b\u0103; \u00eemb\u0103tr\u00e2nire cutanat\u0103; scor confocal<\/p>\n
\u00cemb\u0103tr\u00e2nirea cutanat\u0103 este un proces fiziologic complex guvernat de factori intrinseci \u0219i extrinseci. Cre\u0219terea speran\u021bei de via\u021b\u0103 a transformat \u00eemb\u0103tr\u00e2nirea cutanat\u0103 \u00eentr-un subiect de interes pentru popula\u021bia general\u0103. Examenul clinic nu descrie pe deplin acest proces. De\u0219i datele histologice sunt limitate, modific\u0103rile microscopice care apar \u00een procesul de \u00eemb\u0103tr\u00e2nire al pielii pot fi acum observate \u0219i cuantificate direct prin tehnici non-invazive, cum ar fi microscopia confocal\u0103 de reflectan\u021b\u0103 in vivo (MCR). Am conceput un studiu prospectiv observa\u021bional cu scopul de a dezvolta un scor confocal u\u0219or de utilizat pentru cuantificarea semnelor \u00eemb\u0103tr\u00e2nirii cutanate (CSIESA). Datele au fost colectate la \u201eCentrul Medical Panduri\u201d din Bucure\u0219ti, \u00een perioada 07-28.03.2022. Datorit\u0103 naturii pivotale a studiului, am decis s\u0103 \u00eenscriem 30 de subiec\u021bi. Lotul a fost \u00eemp\u0103r\u021bit \u00een 5 grupe de v\u00e2rst\u0103: <35; 36\u201345; 46\u201355; 56\u201365 \u0219i >65 de ani. Semnele clinice au fost cuantificate folosind scorul \u201eSCINEXA\u201d. Au fost evaluate variabilele confocale cunoscute ale \u00eemb\u0103tr\u00e2nirii cutanate. Am calculat trei scoruri semi-cantitative diferite: scorul dezorganiz\u0103rii epidermice (EDS), scorul hiperplaziei epidermice (EHS) \u0219i scorul dermal (DS). EDS a ar\u0103tat o tendin\u021b\u0103 stabil\u0103 p\u00e2n\u0103 la v\u00e2rsta de 65 de ani \u0219i o cre\u0219tere dramatic\u0103 la subiec\u021bii >65 ani. EHS a fost caracterizat de o tendin\u021b\u0103 ascendent\u0103 de la subiec\u021bii mai tineri la cei de v\u00e2rst\u0103 mijlocie. DS a crescut liniar cu v\u00e2rsta, cu o propor\u021bie diferit\u0103 a tipurilor de colagen. Scorul confocal CSIESA s-a corelat bine cu scorul clinic SCINEXA. MCR este o tehnic\u0103 non-invaziv\u0103 aplicabil\u0103 pentru cuantificarea microscopic\u0103 a semnelor de \u00eemb\u0103tr\u00e2nire cutanat\u0103.<\/p>\n
The CSIESA: A novel score for the assessment of intrinsic and extrinsic skin aging based on reflectance confocal microscopy imaging<\/span>
Authora: V.M. Voiculescu1,2, A.M. Malciu2, L. Banciu2, E.C. Dobric\u01032, M. Lupu1,3<\/span>
1Department of Dermatology, “Carol Davila” University of Medicine and Pharmacy Bucharest, Romania
2Clinic of Oncological Dermatology and Clinical Immunology, Elias University Emergency Hospital, Bucharest, Romania
3Department of Dermatology, Med-As Medical Center, Bucharest, Romania<\/p>\nKeywords: reflectance confocal microscopy, cheilitis, lichen, erythroplasia, psoriasis<\/p>\n
Skin ageing is an intricate physiologic process that is governed by intrinsic (chronoageing) and extrinsic factors. Increasing life expectancy have turned skin aging into a topic of growing concern for the general population. Clinical examination of the skin does not fully describe the skin ageing process. Although histological data is limited, the microscopic changes occurring during skin ageing can now be directly observed and quantified through non-invasive techniques, such as in vivo reflectance confocal microscopy (RCM). An observational prospective study was designed with the aim of developing an easy to use confocal score to quantify skin ageing related signs (\u201cCSIESA\u201d). Data were collected at \u201cCentrul Medical Panduri\u201d Clinic in Bucharest between 07- 28.03.2022. Due to the pivotal nature of the study, we decided to empirically enroll 30 subjects. The study population was split into 5 age groups: <35; 36\u201345; 46\u201355; 56\u201365 and >65 years old. Clinical signs were quantified using the \u201cSCINEXA\u201d score. Known confocal variables of skin ageing were evaluated. Three different semi-quantitative scores were calculated: epidermal disarrangement score (EDS), epidermal hyperplasia score (EHS), and dermal score (DS). The EDS showed a stable trend up to the age of 65 and a dramatic increase in older subjects. EHS was characterized by an ascending trend from younger subjects to middle aged ones. The DS was progressive with age with a different proportion of distinct collagen type. The confocal \u201cCSIESA\u201d score correlated well with the SCINEXA score. RCM is a powerful, non-invasive technique for microscopically quantifying the ageing signs.<\/p>\n
Scurt CV<\/span><\/p>\nExperien\u021ba Personal\u0103:
2018-prezent – \u0218ef de lucr\u0103ri – Universitatea de Medicin\u0103 \u015fi Farmacie “Carol Davila\u201d Bucure\u015fti, Rom\u00e2nia<\/p>\n
Educa\u0163ie \u015fi formare:
2013 – prezent – Medic primar dermato-venerolog – Spitalul Universitar de Urgen\u0163\u0103 \u201eElias\u201d, Bucure\u015fti
2014 – prezent – Doctor in stiinte medicale – Universitatea de Medicin\u0103 \u015fi Farmacie “Carol Davila\u201d Bucure\u015fti, Rom\u00e2nia<\/p>\n
Membru \u00een organiza\u0163ii profesionale:
\u2022 2015 – prezent: membru al Consiliului director al SRD (Romanian Society of Dermatology)
\u2022 2013 – prezent: membru al European Academy of Dermatology and Venerology (EADV) Alumi Club
\u2022 2011 – prezent: membru al International Dermoscopy Society (IDS)
\u2022 2010 – prezent: membru al EADV (European Academy of Dermatology and Venerology)
\u2022 2008 – prezent: membru al Societ\u0103\u0163ii Romane de Dermatologie
\u2022 2008 – prezent: membru \u00een Colegiul Medicilor din Bucure\u015fti<\/p>\n
Lista lucr\u0103rilor \u015ftiin\u0163ifice publicate:
\u2022 2008 \u2013 prezent: am publicat 21 articole ISI in extenso, 32 de articole IDB (international data-base indexed) in extenso si peste 40 de articole in resumat (prezentate ca postre sau comunicari oreale la diferite manifestari stiintifice nationale sau internationale)
\u2022 2016 \u2013 prezent: speaker invitat la peste 10 manifestari nationale de Dermatologie
\u2022 2008 \u2013 prezent: am participat la peste 18 manifestari stiintifice internationale si peste 20 de manifestari stiintifice nationale (din domeniul meu de activitate)<\/p>\n
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Contacteaz\u0103 operatorul PDI 2022<\/p>\n
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Operatorul PDI 2022<\/p>\n
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<\/span><\/p>\n<\/span><\/p>\n<\/span><\/p>\nAdresa: Str. A. Panu nr. 13, Iasi<\/span>
Tel.: 0332.40.88.00-05<\/span>
E-mail: contact@pdi.ro<\/a>
<\/span>Website:\u00a0<\/span>www.eventernet.ro<\/a><\/p>\n[\/et_pb_text][et_pb_text disabled_on=”on|on|on” _builder_version=”4.16″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” disabled=”on” locked=”off” global_colors_info=”{}”]<\/p>\n
Parteneri Media<\/p>\n
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\u0218ef. Lucr. Dr.\u00a0Voiculescu Vlad Universitatea de Medicin\u0103 \u015fi Farmacie “Carol Davila\u201d Bucure\u015fti, Rom\u00e2niaCSIESA: un nou scor pentru evaluarea \u00eemb\u0103tr\u00e2nirii cutanate intrinseci \u0219i extrinseci bazat pe microscopie confocal\u0103 de reflectan\u021b\u0103 in vivoAutori: V.M. Voiculescu1,2, A.M. Malciu2, L. Banciu2, E.C. Dobric\u01032, M. Lupu1,31 Catedra de Dermatologie, Universitatea de Medicin\u0103 \u0219i Farmacie \u201eCarol Davila\u201d Bucure\u0219ti, Rom\u00e2nia2 Clinica de […]<\/p>\n","protected":false},"author":2,"featured_media":11474,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[12],"tags":[],"class_list":["post-10117","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lectori"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts\/10117","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/comments?post=10117"}],"version-history":[{"count":9,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts\/10117\/revisions"}],"predecessor-version":[{"id":11475,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts\/10117\/revisions\/11475"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/media\/11474"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/media?parent=10117"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/categories?post=10117"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/tags?post=10117"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\u0218ef. Lucr. Dr.\u00a0Voiculescu Vlad<\/span><\/strong>
\n Universitatea de Medicin\u0103 \u015fi Farmacie “Carol Davila\u201d Bucure\u015fti, Rom\u00e2nia<\/span><\/strong><\/h4>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.16″ global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.17.0″ global_colors_info=”{}”]<\/p>\n
CSIESA: un nou scor pentru evaluarea \u00eemb\u0103tr\u00e2nirii cutanate intrinseci \u0219i extrinseci bazat pe microscopie confocal\u0103 de reflectan\u021b\u0103 in vivo<\/span>
Autori: V.M. Voiculescu1,2, A.M. Malciu2, L. Banciu2, E.C. Dobric\u01032, M. Lupu1,3<\/span>
1 Catedra de Dermatologie, Universitatea de Medicin\u0103 \u0219i Farmacie \u201eCarol Davila\u201d Bucure\u0219ti, Rom\u00e2nia
2 Clinica de Dermatologie Oncologic\u0103 \u0219i Imunologie Clinic\u0103, Spitalul Universitar de Urgen\u021b\u0103 Elias, Bucure\u0219ti, Rom\u00e2nia
3 Departamentul de Dermatologie, Centrul Medical Med-As, Bucure\u0219ti, Rom\u00e2nia<\/p>\nCuvinte cheie: microscopie confocal\u0103 de reflectan\u021b\u0103; \u00eemb\u0103tr\u00e2nire cutanat\u0103; scor confocal<\/p>\n
\u00cemb\u0103tr\u00e2nirea cutanat\u0103 este un proces fiziologic complex guvernat de factori intrinseci \u0219i extrinseci. Cre\u0219terea speran\u021bei de via\u021b\u0103 a transformat \u00eemb\u0103tr\u00e2nirea cutanat\u0103 \u00eentr-un subiect de interes pentru popula\u021bia general\u0103. Examenul clinic nu descrie pe deplin acest proces. De\u0219i datele histologice sunt limitate, modific\u0103rile microscopice care apar \u00een procesul de \u00eemb\u0103tr\u00e2nire al pielii pot fi acum observate \u0219i cuantificate direct prin tehnici non-invazive, cum ar fi microscopia confocal\u0103 de reflectan\u021b\u0103 in vivo (MCR). Am conceput un studiu prospectiv observa\u021bional cu scopul de a dezvolta un scor confocal u\u0219or de utilizat pentru cuantificarea semnelor \u00eemb\u0103tr\u00e2nirii cutanate (CSIESA). Datele au fost colectate la \u201eCentrul Medical Panduri\u201d din Bucure\u0219ti, \u00een perioada 07-28.03.2022. Datorit\u0103 naturii pivotale a studiului, am decis s\u0103 \u00eenscriem 30 de subiec\u021bi. Lotul a fost \u00eemp\u0103r\u021bit \u00een 5 grupe de v\u00e2rst\u0103: <35; 36\u201345; 46\u201355; 56\u201365 \u0219i >65 de ani. Semnele clinice au fost cuantificate folosind scorul \u201eSCINEXA\u201d. Au fost evaluate variabilele confocale cunoscute ale \u00eemb\u0103tr\u00e2nirii cutanate. Am calculat trei scoruri semi-cantitative diferite: scorul dezorganiz\u0103rii epidermice (EDS), scorul hiperplaziei epidermice (EHS) \u0219i scorul dermal (DS). EDS a ar\u0103tat o tendin\u021b\u0103 stabil\u0103 p\u00e2n\u0103 la v\u00e2rsta de 65 de ani \u0219i o cre\u0219tere dramatic\u0103 la subiec\u021bii >65 ani. EHS a fost caracterizat de o tendin\u021b\u0103 ascendent\u0103 de la subiec\u021bii mai tineri la cei de v\u00e2rst\u0103 mijlocie. DS a crescut liniar cu v\u00e2rsta, cu o propor\u021bie diferit\u0103 a tipurilor de colagen. Scorul confocal CSIESA s-a corelat bine cu scorul clinic SCINEXA. MCR este o tehnic\u0103 non-invaziv\u0103 aplicabil\u0103 pentru cuantificarea microscopic\u0103 a semnelor de \u00eemb\u0103tr\u00e2nire cutanat\u0103.<\/p>\n
The CSIESA: A novel score for the assessment of intrinsic and extrinsic skin aging based on reflectance confocal microscopy imaging<\/span>
Authora: V.M. Voiculescu1,2, A.M. Malciu2, L. Banciu2, E.C. Dobric\u01032, M. Lupu1,3<\/span>
1Department of Dermatology, “Carol Davila” University of Medicine and Pharmacy Bucharest, Romania
2Clinic of Oncological Dermatology and Clinical Immunology, Elias University Emergency Hospital, Bucharest, Romania
3Department of Dermatology, Med-As Medical Center, Bucharest, Romania<\/p>\nKeywords: reflectance confocal microscopy, cheilitis, lichen, erythroplasia, psoriasis<\/p>\n
Skin ageing is an intricate physiologic process that is governed by intrinsic (chronoageing) and extrinsic factors. Increasing life expectancy have turned skin aging into a topic of growing concern for the general population. Clinical examination of the skin does not fully describe the skin ageing process. Although histological data is limited, the microscopic changes occurring during skin ageing can now be directly observed and quantified through non-invasive techniques, such as in vivo reflectance confocal microscopy (RCM). An observational prospective study was designed with the aim of developing an easy to use confocal score to quantify skin ageing related signs (\u201cCSIESA\u201d). Data were collected at \u201cCentrul Medical Panduri\u201d Clinic in Bucharest between 07- 28.03.2022. Due to the pivotal nature of the study, we decided to empirically enroll 30 subjects. The study population was split into 5 age groups: <35; 36\u201345; 46\u201355; 56\u201365 and >65 years old. Clinical signs were quantified using the \u201cSCINEXA\u201d score. Known confocal variables of skin ageing were evaluated. Three different semi-quantitative scores were calculated: epidermal disarrangement score (EDS), epidermal hyperplasia score (EHS), and dermal score (DS). The EDS showed a stable trend up to the age of 65 and a dramatic increase in older subjects. EHS was characterized by an ascending trend from younger subjects to middle aged ones. The DS was progressive with age with a different proportion of distinct collagen type. The confocal \u201cCSIESA\u201d score correlated well with the SCINEXA score. RCM is a powerful, non-invasive technique for microscopically quantifying the ageing signs.<\/p>\n
Scurt CV<\/span><\/p>\nExperien\u021ba Personal\u0103:
2018-prezent – \u0218ef de lucr\u0103ri – Universitatea de Medicin\u0103 \u015fi Farmacie “Carol Davila\u201d Bucure\u015fti, Rom\u00e2nia<\/p>\n
Educa\u0163ie \u015fi formare:
2013 – prezent – Medic primar dermato-venerolog – Spitalul Universitar de Urgen\u0163\u0103 \u201eElias\u201d, Bucure\u015fti
2014 – prezent – Doctor in stiinte medicale – Universitatea de Medicin\u0103 \u015fi Farmacie “Carol Davila\u201d Bucure\u015fti, Rom\u00e2nia<\/p>\n
Membru \u00een organiza\u0163ii profesionale:
\u2022 2015 – prezent: membru al Consiliului director al SRD (Romanian Society of Dermatology)
\u2022 2013 – prezent: membru al European Academy of Dermatology and Venerology (EADV) Alumi Club
\u2022 2011 – prezent: membru al International Dermoscopy Society (IDS)
\u2022 2010 – prezent: membru al EADV (European Academy of Dermatology and Venerology)
\u2022 2008 – prezent: membru al Societ\u0103\u0163ii Romane de Dermatologie
\u2022 2008 – prezent: membru \u00een Colegiul Medicilor din Bucure\u015fti<\/p>\n
Lista lucr\u0103rilor \u015ftiin\u0163ifice publicate:
\u2022 2008 \u2013 prezent: am publicat 21 articole ISI in extenso, 32 de articole IDB (international data-base indexed) in extenso si peste 40 de articole in resumat (prezentate ca postre sau comunicari oreale la diferite manifestari stiintifice nationale sau internationale)
\u2022 2016 \u2013 prezent: speaker invitat la peste 10 manifestari nationale de Dermatologie
\u2022 2008 \u2013 prezent: am participat la peste 18 manifestari stiintifice internationale si peste 20 de manifestari stiintifice nationale (din domeniul meu de activitate)<\/p>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.9.6″ background_color=”rgba(117,194,33,0.23)” background_image=”https:\/\/pdi.ro\/2022\/wp-content\/uploads\/2021\/05\/PDI2021_header_1920x550px.jpg” background_blend=”multiply” custom_padding=”54px|0px|0|0px|false|false” top_divider_style=”waves2″ top_divider_color=”#ffffff” top_divider_height=”155px” top_divider_height_tablet=”” top_divider_height_phone=”97px” top_divider_height_last_edited=”on|desktop” bottom_divider_style=”waves2″ bottom_divider_color=”#75c221″ bottom_divider_flip=”vertical” bottom_divider_height_tablet=”” bottom_divider_height_phone=”59px” bottom_divider_height_last_edited=”on|desktop” global_module=”9177″ saved_tabs=”all” global_colors_info=”{}”][et_pb_row column_structure=”3_5,2_5″ _builder_version=”4.16″ custom_padding=”61px|0px|69px|0px|false|false” global_colors_info=”{}”][et_pb_column type=”3_5″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” text_line_height=”1.2em” header_font=”||||||||” background_layout=”dark” text_font_size_tablet=”” text_font_size_phone=”” text_font_size_last_edited=”on|desktop” global_colors_info=”{}”]<\/p>\n
Contacteaz\u0103 operatorul PDI 2022<\/p>\n
[\/et_pb_text][et_pb_contact_form email=”contact@pdi.ro\/2019″ submit_button_text=”Trimite mesajul” _builder_version=”4.16″ _unique_id=”794aaef5-e005-432a-99fb-9ca53e06d67b” title_font=”||||||||” custom_button=”on” button_text_color=”#F0622A” global_colors_info=”{}”][et_pb_contact_field field_id=”Name” field_title=”Nume” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Email” field_title=”Adresa de e-mail” field_type=”email” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Message” field_title=”Mesajul dvs.” field_type=”text” fullwidth_field=”on” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][\/et_pb_contact_form][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” global_colors_info=”{}”]<\/p>\n
Operatorul PDI 2022<\/p>\n
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<\/span><\/p>\n<\/span><\/p>\n<\/span><\/p>\nAdresa: Str. A. Panu nr. 13, Iasi<\/span>
Tel.: 0332.40.88.00-05<\/span>
E-mail: contact@pdi.ro<\/a>
<\/span>Website:\u00a0<\/span>www.eventernet.ro<\/a><\/p>\n[\/et_pb_text][et_pb_text disabled_on=”on|on|on” _builder_version=”4.16″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” disabled=”on” locked=”off” global_colors_info=”{}”]<\/p>\n
Parteneri Media<\/p>\n
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\u0218ef. Lucr. Dr.\u00a0Voiculescu Vlad Universitatea de Medicin\u0103 \u015fi Farmacie “Carol Davila\u201d Bucure\u015fti, Rom\u00e2niaCSIESA: un nou scor pentru evaluarea \u00eemb\u0103tr\u00e2nirii cutanate intrinseci \u0219i extrinseci bazat pe microscopie confocal\u0103 de reflectan\u021b\u0103 in vivoAutori: V.M. Voiculescu1,2, A.M. Malciu2, L. Banciu2, E.C. Dobric\u01032, M. Lupu1,31 Catedra de Dermatologie, Universitatea de Medicin\u0103 \u0219i Farmacie \u201eCarol Davila\u201d Bucure\u0219ti, Rom\u00e2nia2 Clinica de […]<\/p>\n","protected":false},"author":2,"featured_media":11474,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[12],"tags":[],"class_list":["post-10117","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lectori"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts\/10117","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/comments?post=10117"}],"version-history":[{"count":9,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts\/10117\/revisions"}],"predecessor-version":[{"id":11475,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts\/10117\/revisions\/11475"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/media\/11474"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/media?parent=10117"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/categories?post=10117"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/tags?post=10117"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Autori: V.M. Voiculescu1,2, A.M. Malciu2, L. Banciu2, E.C. Dobric\u01032, M. Lupu1,3<\/span>
1 Catedra de Dermatologie, Universitatea de Medicin\u0103 \u0219i Farmacie \u201eCarol Davila\u201d Bucure\u0219ti, Rom\u00e2nia
2 Clinica de Dermatologie Oncologic\u0103 \u0219i Imunologie Clinic\u0103, Spitalul Universitar de Urgen\u021b\u0103 Elias, Bucure\u0219ti, Rom\u00e2nia
3 Departamentul de Dermatologie, Centrul Medical Med-As, Bucure\u0219ti, Rom\u00e2nia<\/p>\n
Cuvinte cheie: microscopie confocal\u0103 de reflectan\u021b\u0103; \u00eemb\u0103tr\u00e2nire cutanat\u0103; scor confocal<\/p>\n
\u00cemb\u0103tr\u00e2nirea cutanat\u0103 este un proces fiziologic complex guvernat de factori intrinseci \u0219i extrinseci. Cre\u0219terea speran\u021bei de via\u021b\u0103 a transformat \u00eemb\u0103tr\u00e2nirea cutanat\u0103 \u00eentr-un subiect de interes pentru popula\u021bia general\u0103. Examenul clinic nu descrie pe deplin acest proces. De\u0219i datele histologice sunt limitate, modific\u0103rile microscopice care apar \u00een procesul de \u00eemb\u0103tr\u00e2nire al pielii pot fi acum observate \u0219i cuantificate direct prin tehnici non-invazive, cum ar fi microscopia confocal\u0103 de reflectan\u021b\u0103 in vivo (MCR). Am conceput un studiu prospectiv observa\u021bional cu scopul de a dezvolta un scor confocal u\u0219or de utilizat pentru cuantificarea semnelor \u00eemb\u0103tr\u00e2nirii cutanate (CSIESA). Datele au fost colectate la \u201eCentrul Medical Panduri\u201d din Bucure\u0219ti, \u00een perioada 07-28.03.2022. Datorit\u0103 naturii pivotale a studiului, am decis s\u0103 \u00eenscriem 30 de subiec\u021bi. Lotul a fost \u00eemp\u0103r\u021bit \u00een 5 grupe de v\u00e2rst\u0103: <35; 36\u201345; 46\u201355; 56\u201365 \u0219i >65 de ani. Semnele clinice au fost cuantificate folosind scorul \u201eSCINEXA\u201d. Au fost evaluate variabilele confocale cunoscute ale \u00eemb\u0103tr\u00e2nirii cutanate. Am calculat trei scoruri semi-cantitative diferite: scorul dezorganiz\u0103rii epidermice (EDS), scorul hiperplaziei epidermice (EHS) \u0219i scorul dermal (DS). EDS a ar\u0103tat o tendin\u021b\u0103 stabil\u0103 p\u00e2n\u0103 la v\u00e2rsta de 65 de ani \u0219i o cre\u0219tere dramatic\u0103 la subiec\u021bii >65 ani. EHS a fost caracterizat de o tendin\u021b\u0103 ascendent\u0103 de la subiec\u021bii mai tineri la cei de v\u00e2rst\u0103 mijlocie. DS a crescut liniar cu v\u00e2rsta, cu o propor\u021bie diferit\u0103 a tipurilor de colagen. Scorul confocal CSIESA s-a corelat bine cu scorul clinic SCINEXA. MCR este o tehnic\u0103 non-invaziv\u0103 aplicabil\u0103 pentru cuantificarea microscopic\u0103 a semnelor de \u00eemb\u0103tr\u00e2nire cutanat\u0103.<\/p>\n
The CSIESA: A novel score for the assessment of intrinsic and extrinsic skin aging based on reflectance confocal microscopy imaging<\/span> Keywords: reflectance confocal microscopy, cheilitis, lichen, erythroplasia, psoriasis<\/p>\n Skin ageing is an intricate physiologic process that is governed by intrinsic (chronoageing) and extrinsic factors. Increasing life expectancy have turned skin aging into a topic of growing concern for the general population. Clinical examination of the skin does not fully describe the skin ageing process. Although histological data is limited, the microscopic changes occurring during skin ageing can now be directly observed and quantified through non-invasive techniques, such as in vivo reflectance confocal microscopy (RCM). An observational prospective study was designed with the aim of developing an easy to use confocal score to quantify skin ageing related signs (\u201cCSIESA\u201d). Data were collected at \u201cCentrul Medical Panduri\u201d Clinic in Bucharest between 07- 28.03.2022. Due to the pivotal nature of the study, we decided to empirically enroll 30 subjects. The study population was split into 5 age groups: <35; 36\u201345; 46\u201355; 56\u201365 and >65 years old. Clinical signs were quantified using the \u201cSCINEXA\u201d score. Known confocal variables of skin ageing were evaluated. Three different semi-quantitative scores were calculated: epidermal disarrangement score (EDS), epidermal hyperplasia score (EHS), and dermal score (DS). The EDS showed a stable trend up to the age of 65 and a dramatic increase in older subjects. EHS was characterized by an ascending trend from younger subjects to middle aged ones. The DS was progressive with age with a different proportion of distinct collagen type. The confocal \u201cCSIESA\u201d score correlated well with the SCINEXA score. RCM is a powerful, non-invasive technique for microscopically quantifying the ageing signs.<\/p>\n Scurt CV<\/span><\/p>\n Experien\u021ba Personal\u0103: Educa\u0163ie \u015fi formare: Membru \u00een organiza\u0163ii profesionale: Lista lucr\u0103rilor \u015ftiin\u0163ifice publicate: [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.9.6″ background_color=”rgba(117,194,33,0.23)” background_image=”https:\/\/pdi.ro\/2022\/wp-content\/uploads\/2021\/05\/PDI2021_header_1920x550px.jpg” background_blend=”multiply” custom_padding=”54px|0px|0|0px|false|false” top_divider_style=”waves2″ top_divider_color=”#ffffff” top_divider_height=”155px” top_divider_height_tablet=”” top_divider_height_phone=”97px” top_divider_height_last_edited=”on|desktop” bottom_divider_style=”waves2″ bottom_divider_color=”#75c221″ bottom_divider_flip=”vertical” bottom_divider_height_tablet=”” bottom_divider_height_phone=”59px” bottom_divider_height_last_edited=”on|desktop” global_module=”9177″ saved_tabs=”all” global_colors_info=”{}”][et_pb_row column_structure=”3_5,2_5″ _builder_version=”4.16″ custom_padding=”61px|0px|69px|0px|false|false” global_colors_info=”{}”][et_pb_column type=”3_5″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” text_line_height=”1.2em” header_font=”||||||||” background_layout=”dark” text_font_size_tablet=”” text_font_size_phone=”” text_font_size_last_edited=”on|desktop” global_colors_info=”{}”]<\/p>\n Contacteaz\u0103 operatorul PDI 2022<\/p>\n [\/et_pb_text][et_pb_contact_form email=”contact@pdi.ro\/2019″ submit_button_text=”Trimite mesajul” _builder_version=”4.16″ _unique_id=”794aaef5-e005-432a-99fb-9ca53e06d67b” title_font=”||||||||” custom_button=”on” button_text_color=”#F0622A” 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button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][\/et_pb_contact_form][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” global_colors_info=”{}”]<\/p>\n Operatorul PDI 2022<\/p>\n [\/et_pb_text][et_pb_text _builder_version=”4.16″ text_font=”||||||||” global_colors_info=”{}”]<\/p>\n <\/span><\/p>\n <\/span><\/p>\n Adresa: Str. A. Panu nr. 13, Iasi<\/span> [\/et_pb_text][et_pb_text disabled_on=”on|on|on” _builder_version=”4.16″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” disabled=”on” locked=”off” global_colors_info=”{}”]<\/p>\n Parteneri Media<\/p>\n [\/et_pb_text][et_pb_gallery gallery_ids=”7203,7204,9252,9464,10156,10157,10556″ fullwidth=”on” disabled_on=”on|on|on” _builder_version=”4.16″ transform_scale=”86%|86%” max_width=”63%” auto=”on” auto_speed=”3500″ hover_transition_duration=”100ms” hover_transition_delay=”50ms” hover_transition_speed_curve=”ease-in-out” disabled=”on” locked=”off” global_colors_info=”{}”][\/et_pb_gallery][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" \u0218ef. Lucr. Dr.\u00a0Voiculescu Vlad Universitatea de Medicin\u0103 \u015fi Farmacie “Carol Davila\u201d Bucure\u015fti, Rom\u00e2niaCSIESA: un nou scor pentru evaluarea \u00eemb\u0103tr\u00e2nirii cutanate intrinseci \u0219i extrinseci bazat pe microscopie confocal\u0103 de reflectan\u021b\u0103 in vivoAutori: V.M. Voiculescu1,2, A.M. Malciu2, L. Banciu2, E.C. Dobric\u01032, M. Lupu1,31 Catedra de Dermatologie, Universitatea de Medicin\u0103 \u0219i Farmacie \u201eCarol Davila\u201d Bucure\u0219ti, Rom\u00e2nia2 Clinica de […]<\/p>\n","protected":false},"author":2,"featured_media":11474,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[12],"tags":[],"class_list":["post-10117","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lectori"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts\/10117","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/comments?post=10117"}],"version-history":[{"count":9,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts\/10117\/revisions"}],"predecessor-version":[{"id":11475,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts\/10117\/revisions\/11475"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/media\/11474"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/media?parent=10117"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/categories?post=10117"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/tags?post=10117"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Authora: V.M. Voiculescu1,2, A.M. Malciu2, L. Banciu2, E.C. Dobric\u01032, M. Lupu1,3<\/span>
1Department of Dermatology, “Carol Davila” University of Medicine and Pharmacy Bucharest, Romania
2Clinic of Oncological Dermatology and Clinical Immunology, Elias University Emergency Hospital, Bucharest, Romania
3Department of Dermatology, Med-As Medical Center, Bucharest, Romania<\/p>\n
2018-prezent – \u0218ef de lucr\u0103ri – Universitatea de Medicin\u0103 \u015fi Farmacie “Carol Davila\u201d Bucure\u015fti, Rom\u00e2nia<\/p>\n
2013 – prezent – Medic primar dermato-venerolog – Spitalul Universitar de Urgen\u0163\u0103 \u201eElias\u201d, Bucure\u015fti
2014 – prezent – Doctor in stiinte medicale – Universitatea de Medicin\u0103 \u015fi Farmacie “Carol Davila\u201d Bucure\u015fti, Rom\u00e2nia<\/p>\n
\u2022 2015 – prezent: membru al Consiliului director al SRD (Romanian Society of Dermatology)
\u2022 2013 – prezent: membru al European Academy of Dermatology and Venerology (EADV) Alumi Club
\u2022 2011 – prezent: membru al International Dermoscopy Society (IDS)
\u2022 2010 – prezent: membru al EADV (European Academy of Dermatology and Venerology)
\u2022 2008 – prezent: membru al Societ\u0103\u0163ii Romane de Dermatologie
\u2022 2008 – prezent: membru \u00een Colegiul Medicilor din Bucure\u015fti<\/p>\n
\u2022 2008 \u2013 prezent: am publicat 21 articole ISI in extenso, 32 de articole IDB (international data-base indexed) in extenso si peste 40 de articole in resumat (prezentate ca postre sau comunicari oreale la diferite manifestari stiintifice nationale sau internationale)
\u2022 2016 \u2013 prezent: speaker invitat la peste 10 manifestari nationale de Dermatologie
\u2022 2008 \u2013 prezent: am participat la peste 18 manifestari stiintifice internationale si peste 20 de manifestari stiintifice nationale (din domeniul meu de activitate)<\/p>\n<\/span><\/p>\n
Tel.: 0332.40.88.00-05<\/span>
E-mail: contact@pdi.ro<\/a>
<\/span>Website:\u00a0<\/span>www.eventernet.ro<\/a><\/p>\n