<\/strong><\/span><\/h4>\n<\/strong><\/span><\/h4>\nProf. Dr. Antoniu Petri\u0219<\/strong><\/span>
Universitatea de Medicin\u0103 \u0219i Farmacie \u201cGrigore T. Popa\u201d Ia\u0219i
Spitalul Clinic de Urgen\u021b\u0103 “Sf. Spiridon” Ia\u0219i<\/strong><\/span><\/h4>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.16″ locked=”off” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.17.1″ global_colors_info=”{}”]<\/p>\n
Simpozion Alfasigma<\/span><\/p>\n\u2018\u2019ROLUL SULODEXID IN AFECTIUNILE VASCULARE\u2018\u2019!
Lectori: A.O. Petri\u0219, D.C.\u00a0 Br\u0103ni\u0219teanu
<\/span><\/span><\/p>\nBoala venoasa cronica netratata poate avea o evolutie progresiva avand un impact semnificativ asupra calitatii vietii pacientilor.
Factorii de risc ai bolii venoase impreuna cu stresul tensional, determina alterarea morfologica si functionala a glicocalixului endotelial si a endoteliului contribuind astfel la dezvoltarea bolii venoase.
In boala venoasa cronica hipertensiunea venoasa va activa tromboza, inflamatia parietala si remodelarea vasculara.
Tratamentul cu glicozaminoglicani (ex. Vessel Due F\u00ae \u2013 sulodexid original, considerat un precursor natural de glicocalix, un glicozaminoglican compozit 80% heparan-sulfat si 20% dermatan-sulfat) poate reface si mentine integritatea glicocalixului endotelial.<\/p>\n
Diabetul zaharat este o patologie care poate duce frecvent la complicatii microvasculare, precum picior diabetic, retinopatie diabetica si nefropatie diabetica (boala renala cronica), ca urmare a stresului chimic si metabolic generat de valorile crescute ale glicemiei asociate cresterii rezistentei tisulare la insulina.<\/p>\n
In cazul unui pacient cu retinopatie diabetica masurile terapeutice trebuie sa vizeze in primul rand eliminarea\/reducerea factorilor de risc, limitarea evolutiei leziunilor vasculare, ameliorarea hemodinamicii si refacerea structurii peretelui vascular.<\/p>\n
Tratamentul cu Vessel Due F\u00ae a inregistrat o crestere semnificativa a grosimii stratului de glicocalix masurat la nivelul vaselor retiniene, sustinand in acest fel caracterul vasculotrop marcant in refacerea endoteliului si a glicocalixului vascular, cu ameliorarea consecutiva a hemodinamicii si a functiei endoteliale.<\/p>\n
Untreated chronic venous disease can have a progressive evolution with a significant impact on patients\u2019 quality of life.
The risk factors of venous disease together with the tensional stress, determine the morphological and functional alteration of the endothelial glycocalyx and of the endothelium, thus contributing to the development of venous disease.
In chronic venous disease, venous hypertension will activate thrombosis, parietal inflammation, and vascular remodeling.
Treatment with glycosaminoglycans (eg Vessel Due F\u00ae, considered a natural precursor of glycocalyx, a composite glycosaminoglycan 80% heparan sulfate and 20% dermatan sulfate) can restore and maintain the integrity of the endothelial glycocalyx.<\/p>\n
Diabetes is a condition that can frequently lead to microvascular complications, such as diabetic foot, diabetic retinopathy and diabetic nephropathy (chronic kidney disease), due to chemical and metabolic stress caused by high blood sugar levels associated with increased tissue resistance to insulin.<\/p>\n
In the case of a patient with diabetic retinopathy, the therapeutic measures must primarily aim at eliminating \/ reducing the risk factors, limiting the evolution of the vascular lesions, improving the hemodynamics and restoring the structure of the vascular wall.<\/p>\n
Vessel Due F\u00ae treatment proved a significant increase in the thickness of the glycocalyx layer measured in the retinal vessels, thus supporting the marked vasculotropism in the restoration of the endothelium and vascular glycocalyx, with the consequent improvement of hemodynamics and endothelial function.<\/p>\n
Keywords: original sulodexide, antithrombotic, chronic venous disease, diabetic retinopathy, microvascular complications, vascular lesions, endothelial function.<\/p>\n
\n
Scurt CV<\/span><\/p>\n\u2022 Profesor universitar, din octombrie 2016 la Universitatea de Medicina si Farmacie \u201eGrigore T. Popa\u201d Iasi\u00a0
\u2022 Medic primar cardiolog – Spitalul Clinic Judetean de Urgenta \u201eSf. Spiridon\u201d Iasi, Clinica de Cardiologie
Competen\u0163e \u015ftiin\u0163ifice (din ultimii 10 ani):
\u2022Vicepresedinte al Societatii Rom\u00e2ne de Cardiologie (2017-2020)
Secretarul Societatii Rom\u00e2ne de Cardiologie (2014-2017)
\u2022 Membru in Consiliul de Conducere al Societatii Rom\u00e2ne de Cardiologie (2008-2011, 2014-2017).
\u2022 Secretarul Grupului de Lucru \u201cCardiologie de Urgenta\u201d al Societatii Rom\u00e2ne de Cardiologie (2011-
2014).
\u2022 Presedintele Grupului de Lucru \u201cCardiologie de Urgenta\u201d al Societatii Rom\u00e2ne de Cardiologie (2008-
2011).
\u2022 Secretar al Grupului de Lucru pentru Resuscitare Cardio-Respiratorie al Societatii Rom\u00e2ne de
Cardiologie (2000-2002).
\u2022 Membru fondator (din partea Societatii Rom\u00e2ne de Cardiologie) al Consiliului National Rom\u00e2n de
Resuscitare (Sinaia, 6 noiembrie 1998).
\u2022 Vicepresedinte al Grupului de Lucru pentru Resuscitare Cardio-Respiratorie al Societatii Rom\u00e2ne de
Cardiologie (1995). <\/p>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.9.6″ background_color=”rgba(117,194,33,0.23)” background_image=”https:\/\/pdi.ro\/2022\/wp-content\/uploads\/2021\/05\/PDI2021_header_1920x550px.jpg” background_blend=”multiply” custom_padding=”54px|0px|0|0px|false|false” top_divider_style=”waves2″ top_divider_color=”#ffffff” top_divider_height=”155px” top_divider_height_tablet=”” top_divider_height_phone=”97px” top_divider_height_last_edited=”on|desktop” bottom_divider_style=”waves2″ bottom_divider_color=”#75c221″ bottom_divider_flip=”vertical” bottom_divider_height_tablet=”” bottom_divider_height_phone=”59px” bottom_divider_height_last_edited=”on|desktop” global_module=”9177″ saved_tabs=”all” global_colors_info=”{}”][et_pb_row column_structure=”3_5,2_5″ _builder_version=”4.16″ custom_padding=”61px|0px|69px|0px|false|false” global_colors_info=”{}”][et_pb_column type=”3_5″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” text_line_height=”1.2em” header_font=”||||||||” background_layout=”dark” text_font_size_tablet=”” text_font_size_phone=”” text_font_size_last_edited=”on|desktop” global_colors_info=”{}”]<\/p>\n
Contacteaz\u0103 operatorul PDI 2022<\/p>\n
[\/et_pb_text][et_pb_contact_form email=”contact@pdi.ro\/2019″ submit_button_text=”Trimite mesajul” _builder_version=”4.16″ _unique_id=”794aaef5-e005-432a-99fb-9ca53e06d67b” title_font=”||||||||” custom_button=”on” button_text_color=”#F0622A” global_colors_info=”{}”][et_pb_contact_field field_id=”Name” field_title=”Nume” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Email” field_title=”Adresa de e-mail” field_type=”email” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Message” field_title=”Mesajul dvs.” field_type=”text” fullwidth_field=”on” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][\/et_pb_contact_form][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” global_colors_info=”{}”]<\/p>\n
Operatorul PDI 2022<\/p>\n
[\/et_pb_text][et_pb_text _builder_version=”4.16″ text_font=”||||||||” global_colors_info=”{}”]<\/p>\n
![\"\"](\"https:\/\/pdi.ro\/2022\/wp-content\/uploads\/2020\/02\/eventer_logo_150px.png\")
<\/span><\/p>\n<\/span><\/p>\n<\/span><\/p>\nAdresa: Str. A. Panu nr. 13, Iasi<\/span>
Tel.: 0332.40.88.00-05<\/span>
E-mail: contact@pdi.ro<\/a>
<\/span>Website:\u00a0<\/span>www.eventernet.ro<\/a><\/p>\n[\/et_pb_text][et_pb_text disabled_on=”on|on|on” _builder_version=”4.16″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” disabled=”on” locked=”off” global_colors_info=”{}”]<\/p>\n
Parteneri Media<\/p>\n
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Prof. Dr. Antoniu Petri\u0219Universitatea de Medicin\u0103 \u0219i Farmacie \u201cGrigore T. Popa\u201d Ia\u0219iSpitalul Clinic de Urgen\u021b\u0103 “Sf. Spiridon” Ia\u0219iSimpozion Alfasigma \u2018\u2019ROLUL SULODEXID IN AFECTIUNILE VASCULARE\u2018\u2019!Lectori: A.O. Petri\u0219, D.C.\u00a0 Br\u0103ni\u0219teanu Boala venoasa cronica netratata poate avea o evolutie progresiva avand un impact semnificativ asupra calitatii vietii pacientilor.Factorii de risc ai bolii venoase impreuna cu stresul tensional, determina […]<\/p>\n","protected":false},"author":2,"featured_media":11641,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[12],"tags":[],"class_list":["post-11640","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lectori"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts\/11640","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/comments?post=11640"}],"version-history":[{"count":3,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts\/11640\/revisions"}],"predecessor-version":[{"id":11649,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts\/11640\/revisions\/11649"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/media\/11641"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/media?parent=11640"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/categories?post=11640"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/tags?post=11640"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Prof. Dr. Antoniu Petri\u0219<\/strong><\/span>
Universitatea de Medicin\u0103 \u0219i Farmacie \u201cGrigore T. Popa\u201d Ia\u0219i
Spitalul Clinic de Urgen\u021b\u0103 “Sf. Spiridon” Ia\u0219i<\/strong><\/span><\/h4>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.16″ locked=”off” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.17.1″ global_colors_info=”{}”]<\/p>\n
Simpozion Alfasigma<\/span><\/p>\n\u2018\u2019ROLUL SULODEXID IN AFECTIUNILE VASCULARE\u2018\u2019!
Lectori: A.O. Petri\u0219, D.C.\u00a0 Br\u0103ni\u0219teanu
<\/span><\/span><\/p>\nBoala venoasa cronica netratata poate avea o evolutie progresiva avand un impact semnificativ asupra calitatii vietii pacientilor.
Factorii de risc ai bolii venoase impreuna cu stresul tensional, determina alterarea morfologica si functionala a glicocalixului endotelial si a endoteliului contribuind astfel la dezvoltarea bolii venoase.
In boala venoasa cronica hipertensiunea venoasa va activa tromboza, inflamatia parietala si remodelarea vasculara.
Tratamentul cu glicozaminoglicani (ex. Vessel Due F\u00ae \u2013 sulodexid original, considerat un precursor natural de glicocalix, un glicozaminoglican compozit 80% heparan-sulfat si 20% dermatan-sulfat) poate reface si mentine integritatea glicocalixului endotelial.<\/p>\n
Diabetul zaharat este o patologie care poate duce frecvent la complicatii microvasculare, precum picior diabetic, retinopatie diabetica si nefropatie diabetica (boala renala cronica), ca urmare a stresului chimic si metabolic generat de valorile crescute ale glicemiei asociate cresterii rezistentei tisulare la insulina.<\/p>\n
In cazul unui pacient cu retinopatie diabetica masurile terapeutice trebuie sa vizeze in primul rand eliminarea\/reducerea factorilor de risc, limitarea evolutiei leziunilor vasculare, ameliorarea hemodinamicii si refacerea structurii peretelui vascular.<\/p>\n
Tratamentul cu Vessel Due F\u00ae a inregistrat o crestere semnificativa a grosimii stratului de glicocalix masurat la nivelul vaselor retiniene, sustinand in acest fel caracterul vasculotrop marcant in refacerea endoteliului si a glicocalixului vascular, cu ameliorarea consecutiva a hemodinamicii si a functiei endoteliale.<\/p>\n
Untreated chronic venous disease can have a progressive evolution with a significant impact on patients\u2019 quality of life.
The risk factors of venous disease together with the tensional stress, determine the morphological and functional alteration of the endothelial glycocalyx and of the endothelium, thus contributing to the development of venous disease.
In chronic venous disease, venous hypertension will activate thrombosis, parietal inflammation, and vascular remodeling.
Treatment with glycosaminoglycans (eg Vessel Due F\u00ae, considered a natural precursor of glycocalyx, a composite glycosaminoglycan 80% heparan sulfate and 20% dermatan sulfate) can restore and maintain the integrity of the endothelial glycocalyx.<\/p>\n
Diabetes is a condition that can frequently lead to microvascular complications, such as diabetic foot, diabetic retinopathy and diabetic nephropathy (chronic kidney disease), due to chemical and metabolic stress caused by high blood sugar levels associated with increased tissue resistance to insulin.<\/p>\n
In the case of a patient with diabetic retinopathy, the therapeutic measures must primarily aim at eliminating \/ reducing the risk factors, limiting the evolution of the vascular lesions, improving the hemodynamics and restoring the structure of the vascular wall.<\/p>\n
Vessel Due F\u00ae treatment proved a significant increase in the thickness of the glycocalyx layer measured in the retinal vessels, thus supporting the marked vasculotropism in the restoration of the endothelium and vascular glycocalyx, with the consequent improvement of hemodynamics and endothelial function.<\/p>\n
Keywords: original sulodexide, antithrombotic, chronic venous disease, diabetic retinopathy, microvascular complications, vascular lesions, endothelial function.<\/p>\n
\n
Scurt CV<\/span><\/p>\n\u2022 Profesor universitar, din octombrie 2016 la Universitatea de Medicina si Farmacie \u201eGrigore T. Popa\u201d Iasi\u00a0
\u2022 Medic primar cardiolog – Spitalul Clinic Judetean de Urgenta \u201eSf. Spiridon\u201d Iasi, Clinica de Cardiologie
Competen\u0163e \u015ftiin\u0163ifice (din ultimii 10 ani):
\u2022Vicepresedinte al Societatii Rom\u00e2ne de Cardiologie (2017-2020)
Secretarul Societatii Rom\u00e2ne de Cardiologie (2014-2017)
\u2022 Membru in Consiliul de Conducere al Societatii Rom\u00e2ne de Cardiologie (2008-2011, 2014-2017).
\u2022 Secretarul Grupului de Lucru \u201cCardiologie de Urgenta\u201d al Societatii Rom\u00e2ne de Cardiologie (2011-
2014).
\u2022 Presedintele Grupului de Lucru \u201cCardiologie de Urgenta\u201d al Societatii Rom\u00e2ne de Cardiologie (2008-
2011).
\u2022 Secretar al Grupului de Lucru pentru Resuscitare Cardio-Respiratorie al Societatii Rom\u00e2ne de
Cardiologie (2000-2002).
\u2022 Membru fondator (din partea Societatii Rom\u00e2ne de Cardiologie) al Consiliului National Rom\u00e2n de
Resuscitare (Sinaia, 6 noiembrie 1998).
\u2022 Vicepresedinte al Grupului de Lucru pentru Resuscitare Cardio-Respiratorie al Societatii Rom\u00e2ne de
Cardiologie (1995). <\/p>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.9.6″ background_color=”rgba(117,194,33,0.23)” background_image=”https:\/\/pdi.ro\/2022\/wp-content\/uploads\/2021\/05\/PDI2021_header_1920x550px.jpg” background_blend=”multiply” custom_padding=”54px|0px|0|0px|false|false” top_divider_style=”waves2″ top_divider_color=”#ffffff” top_divider_height=”155px” top_divider_height_tablet=”” top_divider_height_phone=”97px” top_divider_height_last_edited=”on|desktop” bottom_divider_style=”waves2″ bottom_divider_color=”#75c221″ bottom_divider_flip=”vertical” bottom_divider_height_tablet=”” bottom_divider_height_phone=”59px” bottom_divider_height_last_edited=”on|desktop” global_module=”9177″ saved_tabs=”all” global_colors_info=”{}”][et_pb_row column_structure=”3_5,2_5″ _builder_version=”4.16″ custom_padding=”61px|0px|69px|0px|false|false” global_colors_info=”{}”][et_pb_column type=”3_5″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” text_line_height=”1.2em” header_font=”||||||||” background_layout=”dark” text_font_size_tablet=”” text_font_size_phone=”” text_font_size_last_edited=”on|desktop” global_colors_info=”{}”]<\/p>\n
Contacteaz\u0103 operatorul PDI 2022<\/p>\n
[\/et_pb_text][et_pb_contact_form email=”contact@pdi.ro\/2019″ submit_button_text=”Trimite mesajul” _builder_version=”4.16″ _unique_id=”794aaef5-e005-432a-99fb-9ca53e06d67b” title_font=”||||||||” custom_button=”on” button_text_color=”#F0622A” global_colors_info=”{}”][et_pb_contact_field field_id=”Name” field_title=”Nume” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Email” field_title=”Adresa de e-mail” field_type=”email” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Message” field_title=”Mesajul dvs.” field_type=”text” fullwidth_field=”on” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][\/et_pb_contact_form][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” global_colors_info=”{}”]<\/p>\n
Operatorul PDI 2022<\/p>\n
[\/et_pb_text][et_pb_text _builder_version=”4.16″ text_font=”||||||||” global_colors_info=”{}”]<\/p>\n
<\/span><\/p>\n<\/span><\/p>\n<\/span><\/p>\nAdresa: Str. A. Panu nr. 13, Iasi<\/span>
Tel.: 0332.40.88.00-05<\/span>
E-mail: contact@pdi.ro<\/a>
<\/span>Website:\u00a0<\/span>www.eventernet.ro<\/a><\/p>\n[\/et_pb_text][et_pb_text disabled_on=”on|on|on” _builder_version=”4.16″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” disabled=”on” locked=”off” global_colors_info=”{}”]<\/p>\n
Parteneri Media<\/p>\n
[\/et_pb_text][et_pb_gallery gallery_ids=”9252,9464,10556″ fullwidth=”on” disabled_on=”off|off|off” _builder_version=”4.17.1″ transform_scale=”86%|86%” max_width=”63%” auto=”on” auto_speed=”3500″ hover_transition_duration=”100ms” hover_transition_delay=”50ms” hover_transition_speed_curve=”ease-in-out” locked=”off” global_colors_info=”{}”][\/et_pb_gallery][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"
Prof. Dr. Antoniu Petri\u0219Universitatea de Medicin\u0103 \u0219i Farmacie \u201cGrigore T. Popa\u201d Ia\u0219iSpitalul Clinic de Urgen\u021b\u0103 “Sf. Spiridon” Ia\u0219iSimpozion Alfasigma \u2018\u2019ROLUL SULODEXID IN AFECTIUNILE VASCULARE\u2018\u2019!Lectori: A.O. Petri\u0219, D.C.\u00a0 Br\u0103ni\u0219teanu Boala venoasa cronica netratata poate avea o evolutie progresiva avand un impact semnificativ asupra calitatii vietii pacientilor.Factorii de risc ai bolii venoase impreuna cu stresul tensional, determina […]<\/p>\n","protected":false},"author":2,"featured_media":11641,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[12],"tags":[],"class_list":["post-11640","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lectori"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts\/11640","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/comments?post=11640"}],"version-history":[{"count":3,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts\/11640\/revisions"}],"predecessor-version":[{"id":11649,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts\/11640\/revisions\/11649"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/media\/11641"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/media?parent=11640"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/categories?post=11640"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/tags?post=11640"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\u2018\u2019ROLUL SULODEXID IN AFECTIUNILE VASCULARE\u2018\u2019! Boala venoasa cronica netratata poate avea o evolutie progresiva avand un impact semnificativ asupra calitatii vietii pacientilor. Diabetul zaharat este o patologie care poate duce frecvent la complicatii microvasculare, precum picior diabetic, retinopatie diabetica si nefropatie diabetica (boala renala cronica), ca urmare a stresului chimic si metabolic generat de valorile crescute ale glicemiei asociate cresterii rezistentei tisulare la insulina.<\/p>\n In cazul unui pacient cu retinopatie diabetica masurile terapeutice trebuie sa vizeze in primul rand eliminarea\/reducerea factorilor de risc, limitarea evolutiei leziunilor vasculare, ameliorarea hemodinamicii si refacerea structurii peretelui vascular.<\/p>\n Tratamentul cu Vessel Due F\u00ae a inregistrat o crestere semnificativa a grosimii stratului de glicocalix masurat la nivelul vaselor retiniene, sustinand in acest fel caracterul vasculotrop marcant in refacerea endoteliului si a glicocalixului vascular, cu ameliorarea consecutiva a hemodinamicii si a functiei endoteliale.<\/p>\n Untreated chronic venous disease can have a progressive evolution with a significant impact on patients\u2019 quality of life. Diabetes is a condition that can frequently lead to microvascular complications, such as diabetic foot, diabetic retinopathy and diabetic nephropathy (chronic kidney disease), due to chemical and metabolic stress caused by high blood sugar levels associated with increased tissue resistance to insulin.<\/p>\n In the case of a patient with diabetic retinopathy, the therapeutic measures must primarily aim at eliminating \/ reducing the risk factors, limiting the evolution of the vascular lesions, improving the hemodynamics and restoring the structure of the vascular wall.<\/p>\n Vessel Due F\u00ae treatment proved a significant increase in the thickness of the glycocalyx layer measured in the retinal vessels, thus supporting the marked vasculotropism in the restoration of the endothelium and vascular glycocalyx, with the consequent improvement of hemodynamics and endothelial function.<\/p>\n Keywords: original sulodexide, antithrombotic, chronic venous disease, diabetic retinopathy, microvascular complications, vascular lesions, endothelial function.<\/p>\n \n Scurt CV<\/span><\/p>\n \u2022 Profesor universitar, din octombrie 2016 la Universitatea de Medicina si Farmacie \u201eGrigore T. Popa\u201d Iasi\u00a0 [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.9.6″ background_color=”rgba(117,194,33,0.23)” background_image=”https:\/\/pdi.ro\/2022\/wp-content\/uploads\/2021\/05\/PDI2021_header_1920x550px.jpg” background_blend=”multiply” custom_padding=”54px|0px|0|0px|false|false” top_divider_style=”waves2″ top_divider_color=”#ffffff” top_divider_height=”155px” top_divider_height_tablet=”” top_divider_height_phone=”97px” top_divider_height_last_edited=”on|desktop” bottom_divider_style=”waves2″ bottom_divider_color=”#75c221″ bottom_divider_flip=”vertical” bottom_divider_height_tablet=”” bottom_divider_height_phone=”59px” bottom_divider_height_last_edited=”on|desktop” global_module=”9177″ saved_tabs=”all” global_colors_info=”{}”][et_pb_row column_structure=”3_5,2_5″ _builder_version=”4.16″ custom_padding=”61px|0px|69px|0px|false|false” global_colors_info=”{}”][et_pb_column type=”3_5″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” text_line_height=”1.2em” header_font=”||||||||” background_layout=”dark” text_font_size_tablet=”” text_font_size_phone=”” text_font_size_last_edited=”on|desktop” global_colors_info=”{}”]<\/p>\n Contacteaz\u0103 operatorul PDI 2022<\/p>\n [\/et_pb_text][et_pb_contact_form email=”contact@pdi.ro\/2019″ submit_button_text=”Trimite mesajul” _builder_version=”4.16″ _unique_id=”794aaef5-e005-432a-99fb-9ca53e06d67b” title_font=”||||||||” custom_button=”on” button_text_color=”#F0622A” global_colors_info=”{}”][et_pb_contact_field field_id=”Name” field_title=”Nume” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Email” field_title=”Adresa de e-mail” field_type=”email” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Message” field_title=”Mesajul dvs.” field_type=”text” fullwidth_field=”on” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][\/et_pb_contact_form][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” global_colors_info=”{}”]<\/p>\n Operatorul PDI 2022<\/p>\n [\/et_pb_text][et_pb_text _builder_version=”4.16″ text_font=”||||||||” global_colors_info=”{}”]<\/p>\n <\/span><\/p>\n <\/span><\/p>\n Adresa: Str. A. Panu nr. 13, Iasi<\/span> [\/et_pb_text][et_pb_text disabled_on=”on|on|on” _builder_version=”4.16″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” disabled=”on” locked=”off” global_colors_info=”{}”]<\/p>\n Parteneri Media<\/p>\n [\/et_pb_text][et_pb_gallery gallery_ids=”9252,9464,10556″ fullwidth=”on” disabled_on=”off|off|off” _builder_version=”4.17.1″ transform_scale=”86%|86%” max_width=”63%” auto=”on” auto_speed=”3500″ hover_transition_duration=”100ms” hover_transition_delay=”50ms” hover_transition_speed_curve=”ease-in-out” locked=”off” global_colors_info=”{}”][\/et_pb_gallery][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" Prof. Dr. Antoniu Petri\u0219Universitatea de Medicin\u0103 \u0219i Farmacie \u201cGrigore T. Popa\u201d Ia\u0219iSpitalul Clinic de Urgen\u021b\u0103 “Sf. Spiridon” Ia\u0219iSimpozion Alfasigma \u2018\u2019ROLUL SULODEXID IN AFECTIUNILE VASCULARE\u2018\u2019!Lectori: A.O. Petri\u0219, D.C.\u00a0 Br\u0103ni\u0219teanu Boala venoasa cronica netratata poate avea o evolutie progresiva avand un impact semnificativ asupra calitatii vietii pacientilor.Factorii de risc ai bolii venoase impreuna cu stresul tensional, determina […]<\/p>\n","protected":false},"author":2,"featured_media":11641,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[12],"tags":[],"class_list":["post-11640","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lectori"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts\/11640","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/comments?post=11640"}],"version-history":[{"count":3,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts\/11640\/revisions"}],"predecessor-version":[{"id":11649,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts\/11640\/revisions\/11649"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/media\/11641"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/media?parent=11640"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/categories?post=11640"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/tags?post=11640"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Lectori: A.O. Petri\u0219, D.C.\u00a0 Br\u0103ni\u0219teanu
<\/span><\/span><\/p>\n
Factorii de risc ai bolii venoase impreuna cu stresul tensional, determina alterarea morfologica si functionala a glicocalixului endotelial si a endoteliului contribuind astfel la dezvoltarea bolii venoase.
In boala venoasa cronica hipertensiunea venoasa va activa tromboza, inflamatia parietala si remodelarea vasculara.
Tratamentul cu glicozaminoglicani (ex. Vessel Due F\u00ae \u2013 sulodexid original, considerat un precursor natural de glicocalix, un glicozaminoglican compozit 80% heparan-sulfat si 20% dermatan-sulfat) poate reface si mentine integritatea glicocalixului endotelial.<\/p>\n
The risk factors of venous disease together with the tensional stress, determine the morphological and functional alteration of the endothelial glycocalyx and of the endothelium, thus contributing to the development of venous disease.
In chronic venous disease, venous hypertension will activate thrombosis, parietal inflammation, and vascular remodeling.
Treatment with glycosaminoglycans (eg Vessel Due F\u00ae, considered a natural precursor of glycocalyx, a composite glycosaminoglycan 80% heparan sulfate and 20% dermatan sulfate) can restore and maintain the integrity of the endothelial glycocalyx.<\/p>\n
\u2022 Medic primar cardiolog – Spitalul Clinic Judetean de Urgenta \u201eSf. Spiridon\u201d Iasi, Clinica de Cardiologie
Competen\u0163e \u015ftiin\u0163ifice (din ultimii 10 ani):
\u2022Vicepresedinte al Societatii Rom\u00e2ne de Cardiologie (2017-2020)
Secretarul Societatii Rom\u00e2ne de Cardiologie (2014-2017)
\u2022 Membru in Consiliul de Conducere al Societatii Rom\u00e2ne de Cardiologie (2008-2011, 2014-2017).
\u2022 Secretarul Grupului de Lucru \u201cCardiologie de Urgenta\u201d al Societatii Rom\u00e2ne de Cardiologie (2011-
2014).
\u2022 Presedintele Grupului de Lucru \u201cCardiologie de Urgenta\u201d al Societatii Rom\u00e2ne de Cardiologie (2008-
2011).
\u2022 Secretar al Grupului de Lucru pentru Resuscitare Cardio-Respiratorie al Societatii Rom\u00e2ne de
Cardiologie (2000-2002).
\u2022 Membru fondator (din partea Societatii Rom\u00e2ne de Cardiologie) al Consiliului National Rom\u00e2n de
Resuscitare (Sinaia, 6 noiembrie 1998).
\u2022 Vicepresedinte al Grupului de Lucru pentru Resuscitare Cardio-Respiratorie al Societatii Rom\u00e2ne de
Cardiologie (1995). <\/p>\n<\/span><\/p>\n
Tel.: 0332.40.88.00-05<\/span>
E-mail: contact@pdi.ro<\/a>
<\/span>Website:\u00a0<\/span>www.eventernet.ro<\/a><\/p>\n