<\/span><\/strong><\/h4>\n<\/span><\/strong><\/h4>\nProf. Dr. Tatu Alin Lauren\u021biu<\/span><\/strong>
Facultatea de Medicin\u0103 \u015fi Farmacie din Gala\u0163i, Rom\u00e2nia<\/span><\/strong><\/h4>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.16″ global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.17.0″ global_colors_info=”{}”]<\/p>\n
Consideratii noi privind leziunile cutanate veziculoase din infectia cu sars-cov2 si fenomenul koebner
Autori: Al. Tatu, T Nadasdy, FC Bujoreanu, Diana Sabina Radaschin, LC Nwabudike
<\/span><\/p>\nUniversitatea Dunarea de Jos din Galati- Facultatea de Medicina si Farmacie
Spitalul Clinic de Boli Infectioase \u201cSf Cuv Parascheva\u201d Galati \u2013 Sectia Clinica Dermato-venerologie
Universitatea Dunarea de Jos din Galati – Centrul Integrat Multidisciplinar pentru Cercetare de Interfa\u021b\u0103 Dermatologic\u0103 (CIM-CID)<\/p>\n
ACKNOWLEDGEMENTS: Aceasta lucrare a fost realizata prin sprijinul Universit\u0103\u021bii \u201c Dunarea de Jos\u201d din Galati prin Grantul de cercetare cu nr RF 3668 \/1.10.2021 si a Centrului Integrat Multidisciplinar pentru Cercetare de Interfa\u021b\u0103 Dermatologic\u0103 (CIM-CID)<\/p>\n
Introducere:
Infectia cu virusul SARS-Cov2 s-a asociat recent cu cazuri de reactivare a varicelei. Aceste transformari pot fi puse pe seama unei susceptibilitati locale cutanate in zonele in care se formeaza preponderant vezicule.
Material si metoda
Aceasta lucrare evidentiaza manifestarile cutanate si factorii infectiosi ce au fost asociati infectiei COVID-19. S-a descries conceptul de raspuns izotopic ce poate sa apara in context de imunosupresie, coroborat cu productie crescuta de citokine inflamatorii.
Prezenta unei eruptii cutanate alcatuit preponderent din vezicule debutata brusc la un pacient necesita prudenta, pentru a evita traumatizarea leziunilor, necesitand un plan de ingrijiri adecvat, pentru a evita fenomenul de autoinoculare sau dezvoltare a unei reactii de tip Koebner<\/p>\n
Concluzii
Din perspectiva si experienta noastra, tratamentele locale siccative ( cum ar fi mixturile, substantele antiseptic pe baza de alcool, AINS) \uf0e0 pot avea un rol benefic in tratamentul eruptiei alcatuita din vezicule la pacientii COVID-19 pozitivi.<\/p>\n
Keywords : COVID-19, SARS-CoV-2, Koebner phenomenon, wolf isotopic response, vesicular rash<\/p>\n
Introduction
SARS-CoV-2 has recently been associated with the reactivation of varicella zoster virus in patients. This is potentially an observation of a local susceptibility of the skin in areas of vesicle formation<\/p>\n
Materials and methods
This article explores the dermatologic manifestations that have been linked to the SARS-CoV-2 virus, their infectious risk, as well as potential confounding factors. An isotopic response may be occurring due to the occurrence of an immunocompromised district incited by sustained inflammation mediated by inflammatory cytokines. The presence of vesicular lesions on a patient should call for prudence in order to avoid traumatizing these lesions and maintain a traditional approach to local therapy by using treatments that are desiccating, recommendation which physicians should offer to their patients in order to avoid autoinoculation or creating a Koebner reaction.<\/p>\n
Conclusions
From this perspective and from our clinical experience, local treatments that are desiccating, such as mixtures, antiseptic alcohol-based solutions, and non-steroidal anti- inflammatory medications, could be recommended for the management of COVID vesicles alongside COVID19 treatment.<\/p>\n
Scurt CV<\/span><\/p>\nN\u0103scut \u00een 1968, urmeaz\u0103 etapele \u015fcolariz\u0103rii fiind absolvent al Liceului de Matematic\u0103-Fizic\u0103 \u201dVasile Alecsandri\u201d Gala\u0163i \u015fi olimpic na\u0163ional la matematic\u0103. Dup\u0103 stagiul militar, studiaz\u0103 apoi la Universitatea de Medicin\u0103 \u015fi Farmacie \u201dCarol Davila\u201d din Bucure\u015fti. Se formeaz\u0103 ca dermatolog \u00een Spitalul Clinic \u201dColentina\u201d sub bagheta Prof. Dr. Forsea, Prof. dr. Giurc\u0103neanu \u015fi a dr. Smaranda Iosif. Ob\u0163ine primul loc la examenul de medic specialist sus\u0163inut la Bucure\u015fti \u015fi de asemenea primul loc la examenul de medic primar sus\u0163inut la Timi\u015foara.
Ob\u0163ine prin concurs postul de medic dermato venerolog la Spitalul de Urgen\u0163\u0103 \u201dSf. Apostol Andrei\u201d din Gala\u0163i \u015fi lucreaz\u0103 \u00een paralel \u00een sistem privat. Se implic\u0103 \u00een dezvoltarea tematicilor \u015fi programelor noii Facult\u0103\u0163i de Medicin\u0103 \u015fi Farmacie din cadrul Universit\u0103\u0163ii \u201dDun\u0103rea de Jos\u201d din Gala\u0163i unde sus\u0163ine ini\u0163ial cursuri \u015fi lucr\u0103ri ca asociat, apoi din 2011 ca titular angajat.
\u00cen 2017 sus\u0163ine Teza de Abilitare \u015fi tot din acel an devine Profesor universitar abilitat al Facult\u0103\u0163ii de Medicin\u0103 \u015fi Farmacie din Gala\u0163i. Din 2018 este conduc\u0103tor de doctorat av\u00e2nd \u00een coordonare 3 doctoranzi \u015fi sus\u0163ine cursuri de studii doctorale avansate \u00een cadrul \u015ecolii Doctorale de \u015etiin\u0163e Fundamentale \u015fi Inginere\u015fti. A publicat numeroase articole de specialitate in extenso indexate ISI, BDI realiz\u00e2nd un indice Hirsch 7 la \u00eenceputul lui 2019.
Este membru al EADV, AAD, EHRS, ISD, ESDR, ESPD \u015fi al Societ\u0103\u0163ii Japoneze de Dermatologie Investigativ\u0103. Este Board Director \u015fi Vicepre\u015fedinte al Societ\u0103\u0163ii Interna\u0163ionale de Dermatologie\u2013ISD.
Domeniile de cercetare de interes sunt reprezentate de Demodex Folliculorum, microbiomul cutanat asociat\/independent de Demodex, Dermoscopia\/Entomodermoscopia, Rozacee, inclusiv cea indus\u0103 steroidian, vitiligo, alter\u0103ri cutanate asociate tulbur\u0103rilor endocrine, prurit, durere cutanat\u0103, alter\u0103ri pilare.<\/p>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.9.6″ background_color=”rgba(117,194,33,0.23)” background_image=”https:\/\/pdi.ro\/2022\/wp-content\/uploads\/2021\/05\/PDI2021_header_1920x550px.jpg” background_blend=”multiply” custom_padding=”54px|0px|0|0px|false|false” top_divider_style=”waves2″ top_divider_color=”#ffffff” top_divider_height=”155px” top_divider_height_tablet=”” top_divider_height_phone=”97px” top_divider_height_last_edited=”on|desktop” bottom_divider_style=”waves2″ bottom_divider_color=”#75c221″ bottom_divider_flip=”vertical” bottom_divider_height_tablet=”” bottom_divider_height_phone=”59px” bottom_divider_height_last_edited=”on|desktop” global_module=”9177″ saved_tabs=”all” global_colors_info=”{}”][et_pb_row column_structure=”3_5,2_5″ _builder_version=”4.16″ custom_padding=”61px|0px|69px|0px|false|false” global_colors_info=”{}”][et_pb_column type=”3_5″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” text_line_height=”1.2em” header_font=”||||||||” background_layout=”dark” text_font_size_tablet=”” text_font_size_phone=”” text_font_size_last_edited=”on|desktop” global_colors_info=”{}”]<\/p>\n
Contacteaz\u0103 operatorul PDI 2022<\/p>\n
[\/et_pb_text][et_pb_contact_form email=”contact@pdi.ro\/2019″ submit_button_text=”Trimite mesajul” _builder_version=”4.16″ _unique_id=”794aaef5-e005-432a-99fb-9ca53e06d67b” title_font=”||||||||” custom_button=”on” button_text_color=”#F0622A” global_colors_info=”{}”][et_pb_contact_field field_id=”Name” field_title=”Nume” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Email” field_title=”Adresa de e-mail” field_type=”email” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Message” field_title=”Mesajul dvs.” field_type=”text” fullwidth_field=”on” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][\/et_pb_contact_form][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” global_colors_info=”{}”]<\/p>\n
Operatorul PDI 2022<\/p>\n
[\/et_pb_text][et_pb_text _builder_version=”4.16″ text_font=”||||||||” global_colors_info=”{}”]<\/p>\n
![\"\"](\"https:\/\/pdi.ro\/2022\/wp-content\/uploads\/2020\/02\/eventer_logo_150px.png\")
<\/span><\/p>\n<\/span><\/p>\n<\/span><\/p>\nAdresa: Str. A. Panu nr. 13, Iasi<\/span>
Tel.: 0332.40.88.00-05<\/span>
E-mail: contact@pdi.ro<\/a>
<\/span>Website:\u00a0<\/span>www.eventernet.ro<\/a><\/p>\n[\/et_pb_text][et_pb_text disabled_on=”on|on|on” _builder_version=”4.16″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” disabled=”on” locked=”off” global_colors_info=”{}”]<\/p>\n
Parteneri Media<\/p>\n
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Prof. Dr. Tatu Alin Lauren\u021biuFacultatea de Medicin\u0103 \u015fi Farmacie din Gala\u0163i, Rom\u00e2niaConsideratii noi privind leziunile cutanate veziculoase din infectia cu sars-cov2 si fenomenul koebnerAutori: Al. Tatu, T Nadasdy, FC Bujoreanu, Diana Sabina Radaschin, LC Nwabudike Universitatea Dunarea de Jos din Galati- Facultatea de Medicina si Farmacie Spitalul Clinic de Boli Infectioase \u201cSf Cuv Parascheva\u201d Galati […]<\/p>\n","protected":false},"author":2,"featured_media":11458,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[12],"tags":[],"class_list":["post-8381","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lectori"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts\/8381","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/comments?post=8381"}],"version-history":[{"count":10,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts\/8381\/revisions"}],"predecessor-version":[{"id":11457,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts\/8381\/revisions\/11457"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/media\/11458"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/media?parent=8381"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/categories?post=8381"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/tags?post=8381"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Prof. Dr. Tatu Alin Lauren\u021biu<\/span><\/strong>
Facultatea de Medicin\u0103 \u015fi Farmacie din Gala\u0163i, Rom\u00e2nia<\/span><\/strong><\/h4>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.16″ global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.17.0″ global_colors_info=”{}”]<\/p>\n
Consideratii noi privind leziunile cutanate veziculoase din infectia cu sars-cov2 si fenomenul koebner
Autori: Al. Tatu, T Nadasdy, FC Bujoreanu, Diana Sabina Radaschin, LC Nwabudike
<\/span><\/p>\nUniversitatea Dunarea de Jos din Galati- Facultatea de Medicina si Farmacie
Spitalul Clinic de Boli Infectioase \u201cSf Cuv Parascheva\u201d Galati \u2013 Sectia Clinica Dermato-venerologie
Universitatea Dunarea de Jos din Galati – Centrul Integrat Multidisciplinar pentru Cercetare de Interfa\u021b\u0103 Dermatologic\u0103 (CIM-CID)<\/p>\n
ACKNOWLEDGEMENTS: Aceasta lucrare a fost realizata prin sprijinul Universit\u0103\u021bii \u201c Dunarea de Jos\u201d din Galati prin Grantul de cercetare cu nr RF 3668 \/1.10.2021 si a Centrului Integrat Multidisciplinar pentru Cercetare de Interfa\u021b\u0103 Dermatologic\u0103 (CIM-CID)<\/p>\n
Introducere:
Infectia cu virusul SARS-Cov2 s-a asociat recent cu cazuri de reactivare a varicelei. Aceste transformari pot fi puse pe seama unei susceptibilitati locale cutanate in zonele in care se formeaza preponderant vezicule.
Material si metoda
Aceasta lucrare evidentiaza manifestarile cutanate si factorii infectiosi ce au fost asociati infectiei COVID-19. S-a descries conceptul de raspuns izotopic ce poate sa apara in context de imunosupresie, coroborat cu productie crescuta de citokine inflamatorii.
Prezenta unei eruptii cutanate alcatuit preponderent din vezicule debutata brusc la un pacient necesita prudenta, pentru a evita traumatizarea leziunilor, necesitand un plan de ingrijiri adecvat, pentru a evita fenomenul de autoinoculare sau dezvoltare a unei reactii de tip Koebner<\/p>\n
Concluzii
Din perspectiva si experienta noastra, tratamentele locale siccative ( cum ar fi mixturile, substantele antiseptic pe baza de alcool, AINS) \uf0e0 pot avea un rol benefic in tratamentul eruptiei alcatuita din vezicule la pacientii COVID-19 pozitivi.<\/p>\n
Keywords : COVID-19, SARS-CoV-2, Koebner phenomenon, wolf isotopic response, vesicular rash<\/p>\n
Introduction
SARS-CoV-2 has recently been associated with the reactivation of varicella zoster virus in patients. This is potentially an observation of a local susceptibility of the skin in areas of vesicle formation<\/p>\n
Materials and methods
This article explores the dermatologic manifestations that have been linked to the SARS-CoV-2 virus, their infectious risk, as well as potential confounding factors. An isotopic response may be occurring due to the occurrence of an immunocompromised district incited by sustained inflammation mediated by inflammatory cytokines. The presence of vesicular lesions on a patient should call for prudence in order to avoid traumatizing these lesions and maintain a traditional approach to local therapy by using treatments that are desiccating, recommendation which physicians should offer to their patients in order to avoid autoinoculation or creating a Koebner reaction.<\/p>\n
Conclusions
From this perspective and from our clinical experience, local treatments that are desiccating, such as mixtures, antiseptic alcohol-based solutions, and non-steroidal anti- inflammatory medications, could be recommended for the management of COVID vesicles alongside COVID19 treatment.<\/p>\n
Scurt CV<\/span><\/p>\nN\u0103scut \u00een 1968, urmeaz\u0103 etapele \u015fcolariz\u0103rii fiind absolvent al Liceului de Matematic\u0103-Fizic\u0103 \u201dVasile Alecsandri\u201d Gala\u0163i \u015fi olimpic na\u0163ional la matematic\u0103. Dup\u0103 stagiul militar, studiaz\u0103 apoi la Universitatea de Medicin\u0103 \u015fi Farmacie \u201dCarol Davila\u201d din Bucure\u015fti. Se formeaz\u0103 ca dermatolog \u00een Spitalul Clinic \u201dColentina\u201d sub bagheta Prof. Dr. Forsea, Prof. dr. Giurc\u0103neanu \u015fi a dr. Smaranda Iosif. Ob\u0163ine primul loc la examenul de medic specialist sus\u0163inut la Bucure\u015fti \u015fi de asemenea primul loc la examenul de medic primar sus\u0163inut la Timi\u015foara.
Ob\u0163ine prin concurs postul de medic dermato venerolog la Spitalul de Urgen\u0163\u0103 \u201dSf. Apostol Andrei\u201d din Gala\u0163i \u015fi lucreaz\u0103 \u00een paralel \u00een sistem privat. Se implic\u0103 \u00een dezvoltarea tematicilor \u015fi programelor noii Facult\u0103\u0163i de Medicin\u0103 \u015fi Farmacie din cadrul Universit\u0103\u0163ii \u201dDun\u0103rea de Jos\u201d din Gala\u0163i unde sus\u0163ine ini\u0163ial cursuri \u015fi lucr\u0103ri ca asociat, apoi din 2011 ca titular angajat.
\u00cen 2017 sus\u0163ine Teza de Abilitare \u015fi tot din acel an devine Profesor universitar abilitat al Facult\u0103\u0163ii de Medicin\u0103 \u015fi Farmacie din Gala\u0163i. Din 2018 este conduc\u0103tor de doctorat av\u00e2nd \u00een coordonare 3 doctoranzi \u015fi sus\u0163ine cursuri de studii doctorale avansate \u00een cadrul \u015ecolii Doctorale de \u015etiin\u0163e Fundamentale \u015fi Inginere\u015fti. A publicat numeroase articole de specialitate in extenso indexate ISI, BDI realiz\u00e2nd un indice Hirsch 7 la \u00eenceputul lui 2019.
Este membru al EADV, AAD, EHRS, ISD, ESDR, ESPD \u015fi al Societ\u0103\u0163ii Japoneze de Dermatologie Investigativ\u0103. Este Board Director \u015fi Vicepre\u015fedinte al Societ\u0103\u0163ii Interna\u0163ionale de Dermatologie\u2013ISD.
Domeniile de cercetare de interes sunt reprezentate de Demodex Folliculorum, microbiomul cutanat asociat\/independent de Demodex, Dermoscopia\/Entomodermoscopia, Rozacee, inclusiv cea indus\u0103 steroidian, vitiligo, alter\u0103ri cutanate asociate tulbur\u0103rilor endocrine, prurit, durere cutanat\u0103, alter\u0103ri pilare.<\/p>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.9.6″ background_color=”rgba(117,194,33,0.23)” background_image=”https:\/\/pdi.ro\/2022\/wp-content\/uploads\/2021\/05\/PDI2021_header_1920x550px.jpg” background_blend=”multiply” custom_padding=”54px|0px|0|0px|false|false” top_divider_style=”waves2″ top_divider_color=”#ffffff” top_divider_height=”155px” top_divider_height_tablet=”” top_divider_height_phone=”97px” top_divider_height_last_edited=”on|desktop” bottom_divider_style=”waves2″ bottom_divider_color=”#75c221″ bottom_divider_flip=”vertical” bottom_divider_height_tablet=”” bottom_divider_height_phone=”59px” bottom_divider_height_last_edited=”on|desktop” global_module=”9177″ saved_tabs=”all” global_colors_info=”{}”][et_pb_row column_structure=”3_5,2_5″ _builder_version=”4.16″ custom_padding=”61px|0px|69px|0px|false|false” global_colors_info=”{}”][et_pb_column type=”3_5″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” text_line_height=”1.2em” header_font=”||||||||” background_layout=”dark” text_font_size_tablet=”” text_font_size_phone=”” text_font_size_last_edited=”on|desktop” global_colors_info=”{}”]<\/p>\n
Contacteaz\u0103 operatorul PDI 2022<\/p>\n
[\/et_pb_text][et_pb_contact_form email=”contact@pdi.ro\/2019″ submit_button_text=”Trimite mesajul” _builder_version=”4.16″ _unique_id=”794aaef5-e005-432a-99fb-9ca53e06d67b” title_font=”||||||||” custom_button=”on” button_text_color=”#F0622A” global_colors_info=”{}”][et_pb_contact_field field_id=”Name” field_title=”Nume” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Email” field_title=”Adresa de e-mail” field_type=”email” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Message” field_title=”Mesajul dvs.” field_type=”text” fullwidth_field=”on” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][\/et_pb_contact_form][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” global_colors_info=”{}”]<\/p>\n
Operatorul PDI 2022<\/p>\n
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<\/span><\/p>\n<\/span><\/p>\n<\/span><\/p>\nAdresa: Str. A. Panu nr. 13, Iasi<\/span>
Tel.: 0332.40.88.00-05<\/span>
E-mail: contact@pdi.ro<\/a>
<\/span>Website:\u00a0<\/span>www.eventernet.ro<\/a><\/p>\n[\/et_pb_text][et_pb_text disabled_on=”on|on|on” _builder_version=”4.16″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” disabled=”on” locked=”off” global_colors_info=”{}”]<\/p>\n
Parteneri Media<\/p>\n
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Prof. Dr. Tatu Alin Lauren\u021biuFacultatea de Medicin\u0103 \u015fi Farmacie din Gala\u0163i, Rom\u00e2niaConsideratii noi privind leziunile cutanate veziculoase din infectia cu sars-cov2 si fenomenul koebnerAutori: Al. Tatu, T Nadasdy, FC Bujoreanu, Diana Sabina Radaschin, LC Nwabudike Universitatea Dunarea de Jos din Galati- Facultatea de Medicina si Farmacie Spitalul Clinic de Boli Infectioase \u201cSf Cuv Parascheva\u201d Galati […]<\/p>\n","protected":false},"author":2,"featured_media":11458,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[12],"tags":[],"class_list":["post-8381","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lectori"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts\/8381","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/comments?post=8381"}],"version-history":[{"count":10,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts\/8381\/revisions"}],"predecessor-version":[{"id":11457,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts\/8381\/revisions\/11457"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/media\/11458"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/media?parent=8381"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/categories?post=8381"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/tags?post=8381"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Autori: Al. Tatu, T Nadasdy, FC Bujoreanu, Diana Sabina Radaschin, LC Nwabudike
<\/span><\/p>\n
Universitatea Dunarea de Jos din Galati- Facultatea de Medicina si Farmacie
Spitalul Clinic de Boli Infectioase \u201cSf Cuv Parascheva\u201d Galati \u2013 Sectia Clinica Dermato-venerologie
Universitatea Dunarea de Jos din Galati – Centrul Integrat Multidisciplinar pentru Cercetare de Interfa\u021b\u0103 Dermatologic\u0103 (CIM-CID)<\/p>\n
ACKNOWLEDGEMENTS: Aceasta lucrare a fost realizata prin sprijinul Universit\u0103\u021bii \u201c Dunarea de Jos\u201d din Galati prin Grantul de cercetare cu nr RF 3668 \/1.10.2021 si a Centrului Integrat Multidisciplinar pentru Cercetare de Interfa\u021b\u0103 Dermatologic\u0103 (CIM-CID)<\/p>\n
Introducere:
Infectia cu virusul SARS-Cov2 s-a asociat recent cu cazuri de reactivare a varicelei. Aceste transformari pot fi puse pe seama unei susceptibilitati locale cutanate in zonele in care se formeaza preponderant vezicule.
Material si metoda
Aceasta lucrare evidentiaza manifestarile cutanate si factorii infectiosi ce au fost asociati infectiei COVID-19. S-a descries conceptul de raspuns izotopic ce poate sa apara in context de imunosupresie, coroborat cu productie crescuta de citokine inflamatorii.
Prezenta unei eruptii cutanate alcatuit preponderent din vezicule debutata brusc la un pacient necesita prudenta, pentru a evita traumatizarea leziunilor, necesitand un plan de ingrijiri adecvat, pentru a evita fenomenul de autoinoculare sau dezvoltare a unei reactii de tip Koebner<\/p>\n
Concluzii
Din perspectiva si experienta noastra, tratamentele locale siccative ( cum ar fi mixturile, substantele antiseptic pe baza de alcool, AINS) \uf0e0 pot avea un rol benefic in tratamentul eruptiei alcatuita din vezicule la pacientii COVID-19 pozitivi.<\/p>\n
Keywords : COVID-19, SARS-CoV-2, Koebner phenomenon, wolf isotopic response, vesicular rash<\/p>\n
Introduction
SARS-CoV-2 has recently been associated with the reactivation of varicella zoster virus in patients. This is potentially an observation of a local susceptibility of the skin in areas of vesicle formation<\/p>\n
Materials and methods
This article explores the dermatologic manifestations that have been linked to the SARS-CoV-2 virus, their infectious risk, as well as potential confounding factors. An isotopic response may be occurring due to the occurrence of an immunocompromised district incited by sustained inflammation mediated by inflammatory cytokines. The presence of vesicular lesions on a patient should call for prudence in order to avoid traumatizing these lesions and maintain a traditional approach to local therapy by using treatments that are desiccating, recommendation which physicians should offer to their patients in order to avoid autoinoculation or creating a Koebner reaction.<\/p>\n
Conclusions
From this perspective and from our clinical experience, local treatments that are desiccating, such as mixtures, antiseptic alcohol-based solutions, and non-steroidal anti- inflammatory medications, could be recommended for the management of COVID vesicles alongside COVID19 treatment.<\/p>\n
Scurt CV<\/span><\/p>\n N\u0103scut \u00een 1968, urmeaz\u0103 etapele \u015fcolariz\u0103rii fiind absolvent al Liceului de Matematic\u0103-Fizic\u0103 \u201dVasile Alecsandri\u201d Gala\u0163i \u015fi olimpic na\u0163ional la matematic\u0103. Dup\u0103 stagiul militar, studiaz\u0103 apoi la Universitatea de Medicin\u0103 \u015fi Farmacie \u201dCarol Davila\u201d din Bucure\u015fti. Se formeaz\u0103 ca dermatolog \u00een Spitalul Clinic \u201dColentina\u201d sub bagheta Prof. Dr. Forsea, Prof. dr. Giurc\u0103neanu \u015fi a dr. Smaranda Iosif. Ob\u0163ine primul loc la examenul de medic specialist sus\u0163inut la Bucure\u015fti \u015fi de asemenea primul loc la examenul de medic primar sus\u0163inut la Timi\u015foara. [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.9.6″ background_color=”rgba(117,194,33,0.23)” background_image=”https:\/\/pdi.ro\/2022\/wp-content\/uploads\/2021\/05\/PDI2021_header_1920x550px.jpg” background_blend=”multiply” custom_padding=”54px|0px|0|0px|false|false” top_divider_style=”waves2″ top_divider_color=”#ffffff” top_divider_height=”155px” top_divider_height_tablet=”” top_divider_height_phone=”97px” top_divider_height_last_edited=”on|desktop” bottom_divider_style=”waves2″ bottom_divider_color=”#75c221″ bottom_divider_flip=”vertical” bottom_divider_height_tablet=”” bottom_divider_height_phone=”59px” bottom_divider_height_last_edited=”on|desktop” global_module=”9177″ saved_tabs=”all” global_colors_info=”{}”][et_pb_row column_structure=”3_5,2_5″ _builder_version=”4.16″ custom_padding=”61px|0px|69px|0px|false|false” global_colors_info=”{}”][et_pb_column type=”3_5″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” text_line_height=”1.2em” header_font=”||||||||” background_layout=”dark” text_font_size_tablet=”” text_font_size_phone=”” text_font_size_last_edited=”on|desktop” global_colors_info=”{}”]<\/p>\n Contacteaz\u0103 operatorul PDI 2022<\/p>\n [\/et_pb_text][et_pb_contact_form email=”contact@pdi.ro\/2019″ submit_button_text=”Trimite mesajul” _builder_version=”4.16″ _unique_id=”794aaef5-e005-432a-99fb-9ca53e06d67b” title_font=”||||||||” custom_button=”on” button_text_color=”#F0622A” global_colors_info=”{}”][et_pb_contact_field field_id=”Name” field_title=”Nume” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” 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A. Panu nr. 13, Iasi<\/span> [\/et_pb_text][et_pb_text disabled_on=”on|on|on” _builder_version=”4.16″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” disabled=”on” locked=”off” global_colors_info=”{}”]<\/p>\n Parteneri Media<\/p>\n [\/et_pb_text][et_pb_gallery gallery_ids=”7203,7204,9252,9464,10156,10157,10556″ fullwidth=”on” disabled_on=”on|on|on” _builder_version=”4.16″ transform_scale=”86%|86%” max_width=”63%” auto=”on” auto_speed=”3500″ hover_transition_duration=”100ms” hover_transition_delay=”50ms” hover_transition_speed_curve=”ease-in-out” disabled=”on” locked=”off” global_colors_info=”{}”][\/et_pb_gallery][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" Prof. Dr. Tatu Alin Lauren\u021biuFacultatea de Medicin\u0103 \u015fi Farmacie din Gala\u0163i, Rom\u00e2niaConsideratii noi privind leziunile cutanate veziculoase din infectia cu sars-cov2 si fenomenul koebnerAutori: Al. Tatu, T Nadasdy, FC Bujoreanu, Diana Sabina Radaschin, LC Nwabudike Universitatea Dunarea de Jos din Galati- Facultatea de Medicina si Farmacie Spitalul Clinic de Boli Infectioase \u201cSf Cuv Parascheva\u201d Galati […]<\/p>\n","protected":false},"author":2,"featured_media":11458,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[12],"tags":[],"class_list":["post-8381","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lectori"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts\/8381","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/comments?post=8381"}],"version-history":[{"count":10,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts\/8381\/revisions"}],"predecessor-version":[{"id":11457,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/posts\/8381\/revisions\/11457"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/media\/11458"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/media?parent=8381"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/categories?post=8381"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pdi.ro\/2022\/wp-json\/wp\/v2\/tags?post=8381"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Ob\u0163ine prin concurs postul de medic dermato venerolog la Spitalul de Urgen\u0163\u0103 \u201dSf. Apostol Andrei\u201d din Gala\u0163i \u015fi lucreaz\u0103 \u00een paralel \u00een sistem privat. Se implic\u0103 \u00een dezvoltarea tematicilor \u015fi programelor noii Facult\u0103\u0163i de Medicin\u0103 \u015fi Farmacie din cadrul Universit\u0103\u0163ii \u201dDun\u0103rea de Jos\u201d din Gala\u0163i unde sus\u0163ine ini\u0163ial cursuri \u015fi lucr\u0103ri ca asociat, apoi din 2011 ca titular angajat.
\u00cen 2017 sus\u0163ine Teza de Abilitare \u015fi tot din acel an devine Profesor universitar abilitat al Facult\u0103\u0163ii de Medicin\u0103 \u015fi Farmacie din Gala\u0163i. Din 2018 este conduc\u0103tor de doctorat av\u00e2nd \u00een coordonare 3 doctoranzi \u015fi sus\u0163ine cursuri de studii doctorale avansate \u00een cadrul \u015ecolii Doctorale de \u015etiin\u0163e Fundamentale \u015fi Inginere\u015fti. A publicat numeroase articole de specialitate in extenso indexate ISI, BDI realiz\u00e2nd un indice Hirsch 7 la \u00eenceputul lui 2019.
Este membru al EADV, AAD, EHRS, ISD, ESDR, ESPD \u015fi al Societ\u0103\u0163ii Japoneze de Dermatologie Investigativ\u0103. Este Board Director \u015fi Vicepre\u015fedinte al Societ\u0103\u0163ii Interna\u0163ionale de Dermatologie\u2013ISD.
Domeniile de cercetare de interes sunt reprezentate de Demodex Folliculorum, microbiomul cutanat asociat\/independent de Demodex, Dermoscopia\/Entomodermoscopia, Rozacee, inclusiv cea indus\u0103 steroidian, vitiligo, alter\u0103ri cutanate asociate tulbur\u0103rilor endocrine, prurit, durere cutanat\u0103, alter\u0103ri pilare.<\/p>\n<\/span><\/p>\n
Tel.: 0332.40.88.00-05<\/span>
E-mail: contact@pdi.ro<\/a>
<\/span>Website:\u00a0<\/span>www.eventernet.ro<\/a><\/p>\n