{"id":7459,"date":"2023-02-14T15:40:51","date_gmt":"2023-02-14T13:40:51","guid":{"rendered":"https:\/\/primaderma.ro\/?page_id=7459"},"modified":"2023-03-15T17:14:20","modified_gmt":"2023-03-15T15:14:20","slug":"prof-dr-ancuceanu-robert","status":"publish","type":"post","link":"https:\/\/pdi.ro\/2023\/prof-dr-ancuceanu-robert\/","title":{"rendered":"Prof. Dr. Ancuceanu Robert"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; fullwidth=&#8221;on&#8221; disabled_on=&#8221;on|off|off&#8221; _builder_version=&#8221;4.19.4&#8243; custom_margin=&#8221;||&#8221; custom_padding=&#8221;15px||29px&#8221; top_divider_style=&#8221;waves2&#8243; top_divider_color=&#8221;#F0622A&#8221; top_divider_flip=&#8221;horizontal|vertical&#8221; bottom_divider_style=&#8221;waves2&#8243; bottom_divider_color=&#8221;#fcdedb&#8221; bottom_divider_height=&#8221;105px&#8221; bottom_divider_flip=&#8221;vertical&#8221; global_module=&#8221;9062&#8243; saved_tabs=&#8221;all&#8221; collapsed=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_fullwidth_header title=&#8221;@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF90aXRsZSIsInNldHRpbmdzIjp7ImJlZm9yZSI6IiIsImFmdGVyIjoiIn19@&#8221; disabled_on=&#8221;on|on|off&#8221; _builder_version=&#8221;4.19.4&#8243; _dynamic_attributes=&#8221;title&#8221; title_font=&#8221;Kaushan Script||||||||&#8221; title_text_align=&#8221;left&#8221; title_text_color=&#8221;#f0622a&#8221; title_font_size=&#8221;55px&#8221; content_font=&#8221;|600||on|||||&#8221; content_text_align=&#8221;center&#8221; content_text_color=&#8221;#686766&#8243; content_font_size=&#8221;15px&#8221; subhead_font=&#8221;||||||||&#8221; background_enable_color=&#8221;off&#8221; background_image=&#8221;https:\/\/pdi.ro\/2023\/wp-content\/uploads\/2022\/12\/PDI2023_header__-scaled.jpg&#8221; background_blend=&#8221;luminosity&#8221; background_layout=&#8221;light&#8221; custom_margin=&#8221;||-5px||false|false&#8221; custom_padding=&#8221;150px||150px||true|false&#8221; content_font_size_tablet=&#8221;&#8221; content_font_size_phone=&#8221;15px&#8221; content_font_size_last_edited=&#8221;on|desktop&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;2_5,3_5&#8243; _builder_version=&#8221;4.16&#8243; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;2_5&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_image src=&#8221;https:\/\/pdi.ro\/2023\/wp-content\/uploads\/2022\/04\/Robert-Ancuceanu-circle.png&#8221; title_text=&#8221;Robert Ancuceanu-circle&#8221; align=&#8221;center&#8221; align_tablet=&#8221;center&#8221; align_phone=&#8221;&#8221; align_last_edited=&#8221;on|desktop&#8221; _builder_version=&#8221;4.19.5&#8243; max_width=&#8221;25%&#8221; border_radii=&#8221;on|100px|100px|100px|100px&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][et_pb_column type=&#8221;3_5&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.16.1&#8243; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h4><span style=\"color: #ff6600;\"><strong><\/strong><\/span><\/h4>\n<h4><span style=\"color: #ff6600;\"><strong><\/strong><\/span><\/h4>\n<h4><span style=\"color: #ff6600;\"><strong><\/strong><\/span><\/h4>\n<h4><span style=\"color: #ff6600;\"><strong>Prof. Dr. Ancuceanu Robert<\/strong><\/span><br \/><span style=\"color: #ff6600;\"><strong>Facultatea de Farmacie, U.M.F. &#8220;Carol Davila&#8221;, Bucure\u015fti<\/strong><\/span><\/h4>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.16&#8243; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.20.2&#8243; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #ff6600;\">Dermatita atopic\u0103 la copii \u0219i microbiomul &#8211; implica\u021bii pentru preven\u021bie \u0219i terapie<\/span><\/p>\n<p><span style=\"color: #ff6600;\"> Autori: R. Ancuceanu, Mihaela Dinu<\/span><br \/>\nUMF \u201eCarol Davila\u201c, Facultatea de Farmacie, Bucure\u0219ti<\/p>\n<p style=\"text-align: justify;\">Cuvinte cheie: microbiom cutanat, dermatit\u0103 atopic\u0103, Staphylococcus aures, Staphylococcus epidermidis, Malassezia<\/p>\n<p>Dermatita atopic\u0103 (DA) este o afec\u021biune cronic\u0103 inflamatorie a pielii care apare cel mai frecvent \u00een copil\u0103rie. Aceasta se caracterizeaz\u0103 prin recuren\u021be \u0219i poate prezenta evolu\u021bii diferite la fiecare pacient, dar \u00een general este asociat\u0103 cu prurit intens. DA pare s\u0103 fie un sindrom rezultat din interac\u021biunea mai multor cauze interconectate, care includ factori inflamatori, func\u021bia de barier\u0103  pielii \u0219i factori microbieni. Desi s-a acordat o atentie sporita explorarii relatiei dintre microbiomul intestinal al copiilor si o serie de patologii sistemice, interesul pentru microbiomul pielii la copii a fost adesea neglijat. Cu toate acestea, \u00een ultimul deceniu au \u00eenceput s\u0103 se acumuleze mai multe date care s\u0103 clarifice diferen\u021bele \u00een structura \u0219i diversitatea microbiomului \u00eentre pacien\u021bii pediatrici cu DA \u0219i cei altminteri s\u0103n\u0103to\u0219i. Datele disponibile p\u00e2n\u0103 acum tind s\u0103 sugereze o disbioz\u0103 pronun\u021bat\u0103 \u00een cursul exacerb\u0103rilor DA, cu o diminuare substan\u021bial\u0103 a diversit\u0103\u021bii microbiene. Mai multe studii (\u00een general cu diverse limit\u0103ri metodologice) au raportat colonizarea sau amplificarea coloniz\u0103rii cu S. aureus \u00een cursul exacerb\u0103rilor, suger\u00e2nd o implicare a acestei specii bacteriene \u00een patologia DA. Exist\u0103 date care sugereaz\u0103 \u0219i o posibil\u0103 implicare a speciilor fungice de Malassezia \u00een apari\u021bia leziunilor DA, dar tiparele observate p\u00e2n\u0103 acum nu se preteaz\u0103 la o interpretare simpl\u0103. Solu\u021bii terapeutice diverse sunt ast\u0103zi evaluate, incluz\u00e2nd utilizarea de probiotice \u0219i alte mijloace de repopulare cu specii microbiene benefice, terapii pe baz\u0103 de fagi, substan\u021be cu molecul\u0103 mic\u0103 sau peptide \u00eempotriva S. aureus. <\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #ff6600;\">Atopic dermatitis in children and the microbiome &#8211; implications for prevention and therapy<\/span><\/p>\n<p><span style=\"color: #ff6600;\">Authors: R. Ancuceanu, Mihaela Dinu<\/span><br \/>\n\u201cCarol Davila\u201d University of Medicine and Pharmacy, Faculty of Pharmacy, Bucharest<\/p>\n<p>Keywords: skin microbiome, atopic dermatitis, Staphylococcus aures, Staphylococcus epidermidis, Malassezia<\/p>\n<p>Atopic dermatitis (AD) is a chronic inflammatory skin condition that most commonly occurs in childhood. It is characterised by recurrences and may present different courses in each patient, but is generally associated with intense itching. AD appears to be a syndrome resulting from the interaction of several interconnected causes, which include inflammatory factors, skin barrier function and microbial factors. Although increased attention has been paid to exploring the relationship between the gut microbiome of children and a range of systemic pathologies, interest in the skin microbiome in children has often been neglected. However, in the last decade more data have begun to accumulate clarifying differences in microbiome structure and diversity between pediatric AD patients and otherwise healthy patients. The data available so far tend to suggest a pronounced dysbiosis during AD exacerbations, with a substantial decrease in microbial diversity. Several studies (generally with various methodological limitations) have reported colonisation or enhanced colonisation with S. aureus during exacerbations, suggesting an involvement of this bacterial species in AD pathology. There are also data suggesting a possible involvement of fungal Malassezia species in the development of AD lesions, but the patterns observed so far do not lend themselves to simple interpretation. Various therapeutic solutions are now being evaluated, including the use of probiotics and other means of repopulation with beneficial microbial species, phage-based therapies, small molecule substances or peptides against S. aureus.<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #ff6600;\">Scurt CV<\/span><\/p>\n<p style=\"text-align: justify;\">Robert Ancuceanu este profesor \u015fi prodecan \u00een cadrul Facult\u0103\u0163ii de Farmacie din Bucure\u015fti, disciplina Botanic\u0103 farmaceutic\u0103 \u015fi biologie celular\u0103. Cu un doctorat \u00een farmacie, un masterat \u00een biostatistic\u0103 \u015fi licen\u0163\u0103 \u00een drept, a lucrat \u00een diferite domenii farmaceutice, de la cel academic la cel industrial \u015fi \u00een cadrul autorit\u0103\u0163ilor de reglementare. A fost director general al Direc\u0163iei Generale Farmaceutice \u015fi Aparatur\u0103 Medical\u0103 din Ministerul S\u0103n\u0103t\u0103\u0163ii \u015fi Vicepre\u015fedinte al Agen\u0163iei Na\u0163ionale a Medicamentului. A fost membru al Comitetului pentru Medicamente de Uz Uman (CHMP) \u015fi al Comitetului Pediatric (PDCO) \u015fi membru altern (supleant) al Comitetului pentru Medicamente pe baz\u0103 de Plante din cadrul Agen\u0163iei Europene a Medicamentului (EMA), precum \u015fi membru \u00een mai multe comitete sau grupuri de lucru din domeniul farmaceutic. A publicat 56 articole \u015ftiin\u0163ifice indexate ISI, este autor a dou\u0103 c\u0103r\u0163i \u015fi co-autor la alte patru. Pe l\u00e2ng\u0103 interesul s\u0103u larg pentru toate aspectele domeniului farmaceutic, Robert se consider\u0103 un renascentist \u00eent\u00e2rziat, fiind interesat \u015fi de drept, istorie, muzic\u0103, biostatistic\u0103 \u0219i machine learning, sociologie \u015fi literatur\u0103.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.19.4&#8243; background_color=&#8221;rgba(240,98,42,0.19)&#8221; background_image=&#8221;https:\/\/pdi.ro\/2023\/wp-content\/uploads\/2022\/12\/PDI2023_header__-scaled.jpg&#8221; background_blend=&#8221;multiply&#8221; custom_padding=&#8221;54px|0px|0|0px|false|false&#8221; top_divider_style=&#8221;waves2&#8243; top_divider_color=&#8221;#ffffff&#8221; top_divider_height=&#8221;155px&#8221; top_divider_height_tablet=&#8221;&#8221; top_divider_height_phone=&#8221;97px&#8221; top_divider_height_last_edited=&#8221;on|desktop&#8221; bottom_divider_style=&#8221;waves2&#8243; bottom_divider_color=&#8221;#F0622A&#8221; 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text_font_size_phone=&#8221;&#8221; text_font_size_last_edited=&#8221;on|desktop&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Contacteaz\u0103 operatorul PDI 2023<\/p>\n<p>[\/et_pb_text][et_pb_contact_form email=&#8221;contact@pdi.ro&#8221; submit_button_text=&#8221;Trimite mesajul&#8221; disabled_on=&#8221;off|off|off&#8221; _builder_version=&#8221;4.20.2&#8243; _unique_id=&#8221;794aaef5-e005-432a-99fb-9ca53e06d67b&#8221; title_font=&#8221;||||||||&#8221; custom_button=&#8221;on&#8221; button_text_color=&#8221;#F0622A&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_contact_field field_id=&#8221;Name&#8221; field_title=&#8221;Nume&#8221; _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221; button_text_size__hover_enabled=&#8221;off&#8221; button_one_text_size__hover_enabled=&#8221;off&#8221; button_two_text_size__hover_enabled=&#8221;off&#8221; button_text_color__hover_enabled=&#8221;off&#8221; button_one_text_color__hover_enabled=&#8221;off&#8221; button_two_text_color__hover_enabled=&#8221;off&#8221; button_border_width__hover_enabled=&#8221;off&#8221; button_one_border_width__hover_enabled=&#8221;off&#8221; button_two_border_width__hover_enabled=&#8221;off&#8221; button_border_color__hover_enabled=&#8221;off&#8221; button_one_border_color__hover_enabled=&#8221;off&#8221; button_two_border_color__hover_enabled=&#8221;off&#8221; button_border_radius__hover_enabled=&#8221;off&#8221; button_one_border_radius__hover_enabled=&#8221;off&#8221; button_two_border_radius__hover_enabled=&#8221;off&#8221; button_letter_spacing__hover_enabled=&#8221;off&#8221; button_one_letter_spacing__hover_enabled=&#8221;off&#8221; button_two_letter_spacing__hover_enabled=&#8221;off&#8221; button_bg_color__hover_enabled=&#8221;off&#8221; button_one_bg_color__hover_enabled=&#8221;off&#8221; button_two_bg_color__hover_enabled=&#8221;off&#8221;][\/et_pb_contact_field][et_pb_contact_field field_id=&#8221;Email&#8221; field_title=&#8221;Adresa de e-mail&#8221; field_type=&#8221;email&#8221; _builder_version=&#8221;4.16&#8243; 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button_bg_color__hover_enabled=&#8221;off&#8221; button_one_bg_color__hover_enabled=&#8221;off&#8221; button_two_bg_color__hover_enabled=&#8221;off&#8221;][\/et_pb_contact_field][et_pb_contact_field field_id=&#8221;Message&#8221; field_title=&#8221;Mesajul dvs.&#8221; field_type=&#8221;text&#8221; fullwidth_field=&#8221;on&#8221; _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221; button_text_size__hover_enabled=&#8221;off&#8221; button_one_text_size__hover_enabled=&#8221;off&#8221; button_two_text_size__hover_enabled=&#8221;off&#8221; button_text_color__hover_enabled=&#8221;off&#8221; button_one_text_color__hover_enabled=&#8221;off&#8221; button_two_text_color__hover_enabled=&#8221;off&#8221; button_border_width__hover_enabled=&#8221;off&#8221; button_one_border_width__hover_enabled=&#8221;off&#8221; button_two_border_width__hover_enabled=&#8221;off&#8221; button_border_color__hover_enabled=&#8221;off&#8221; button_one_border_color__hover_enabled=&#8221;off&#8221; 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background_layout=&#8221;dark&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Operatorul PDI 2023<\/p>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.16&#8243; text_font=&#8221;||||||||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><span><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/pdi.ro\/2023\/2022\/wp-content\/uploads\/2020\/02\/eventer_logo_150px.png\" width=\"151\" height=\"33\" alt=\"\" class=\"wp-image-774 alignleft size-full\" \/><\/span><\/p>\n<p><span><\/span><\/p>\n<p><span><\/span><\/p>\n<p><span>Adresa: Str. A. 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Ancuceanu, Mihaela Dinu UMF \u201eCarol Davila\u201c, Facultatea de Farmacie, Bucure\u0219ti Cuvinte cheie: microbiom cutanat, dermatit\u0103 atopic\u0103, Staphylococcus aures, Staphylococcus epidermidis, Malassezia Dermatita atopic\u0103 (DA) este o afec\u021biune cronic\u0103 inflamatorie a pielii care [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":11334,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[12],"tags":[],"class_list":["post-7459","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lectori"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/posts\/7459","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/comments?post=7459"}],"version-history":[{"count":15,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/posts\/7459\/revisions"}],"predecessor-version":[{"id":12907,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/posts\/7459\/revisions\/12907"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/media\/11334"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/media?parent=7459"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/categories?post=7459"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/tags?post=7459"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}