<\/span><\/strong><\/h4>\n<\/span><\/strong><\/h4>\nProf. Dr. Tatu Alin Lauren\u021biu<\/span><\/strong>
Facultatea de Medicin\u0103 \u015fi Farmacie din Gala\u0163i, Rom\u00e2nia<\/span><\/strong><\/h4>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.16″ global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.20.4″ hover_enabled=”0″ global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n
Profilul in vivo prin Microscopie Confocala de Reflectanta si Tomografie in Coerenta optica al unei tr\u0103s\u0103turi particulare ce caracterizeaz\u0103 carcinomul bazocelular \u2013 separarea tumor\u0103-strom\u0103<\/span><\/p>\nAutori: Elena Niculet1,2, Florin Bujoreanu2,3, Diana Sabina Radaschin2,3,4, Andra Gherghi2,3, Simona Ioana Silion3, Alin Laurentiu Tatu2,4,5
<\/span><\/p>\n1Departmentul de \u0218tiin\u021be Morfologice \u0219i Func\u021bionale, Facultatea de Medicin\u0103 \u0219i Farmacie, Universitatea \u201cDun\u0103rea de Jos\u201d, Gala\u021bi, Rom\u00e2nia
2Centrul Integrat Multidisciplinar de Cercetare de Interfata Dermatologica – CIM-CID, Universitatea \u201cDun\u0103rea de Jos\u201d, Gala\u021bi, Rom\u00e2nia
3Departamentul de Dermatologie \u0219i Venerologie, Spitalul Clinic de Boli Infec\u021bioase “Sf. Cuvioasa Parascheva”, Gala\u021bi, Rom\u00e2nia
4Departamentul Clinic Medical, Facultatea de Medicin\u0103 \u0219i Farmacie, Universitatea \u201cDun\u0103rea de Jos\u201d, Gala\u021bi, Rom\u00e2nia<\/p>\n
Cuvinte cheie: carcinomul bazocelular, tr\u0103s\u0103turi structurale de agresivitate, fant\u0103, separa\u021bie, tomografia de coeren\u021b\u0103 optic\u0103, microscopia confocal\u0103 de reflexie, morfopatologie<\/p>\n
Carcinomul bazocelular este o tumor\u0103 malign\u0103 cutanat\u0103 bine documentat\u0103 \u00een ceea ce prive\u0219te tr\u0103s\u0103turile clinice, aspectele morfopatologice, factorii de prognostic \u0219i op\u021biunile terapeutice. Cercetarea medical\u0103 contemporan\u0103 beneficiaz\u0103 de modalit\u0103\u021bi inovative de diagnostic \u0219i investiga\u021bie a acestor tumori, utiliz\u00e2nd tomografia de coeren\u021b\u0103 optic\u0103 \u0219i microscopia confocal\u0103 de reflexie \u00een scopul identific\u0103rii unor fa\u021bete noi ale carcinomului bazocelular. Datorit\u0103 acestor dou\u0103 tehnici este posibil\u0103 examinarea in vivo a profunzimii invaziei, a marginilor prolifer\u0103rii tumorale anterior exciziei chirurgicale a acesteia, r\u0103spunsul tumorii la tratamentul non-invaziv, precum \u0219i profilul vascular ce caracterizeaza tumora. De asemenea, prin utilizarea acestor dou\u0103 tehnici de examinare s-a descoperit un aspect particular al carcinomului bazocelular: fanta sau artefactul de separare dintre cuiburile tumorale \u0219i stroma \u00eenconjur\u0103toare, despre care s-a crezut ca este un artefact, un rezultat al proces\u0103rii tisulare din laboratorul de morfopatologie, este de fapt o structur\u0103 ce poate fi evaulat\u0103 in vivo, aparent cu identificarea unui material la acest nivel (posibil, mucn\u0103). Este esen\u021bial\u0103 stabilirea rolului acestui aspect structural ca factor prognostic pentru pacient, rolul pe care \u00eel joac\u0103 \u00een evolu\u021bia post-terapeutic\u0103 non-invaziv\u0103 \u0219i dac\u0103 acesta este frecvent \u00eent\u00e2lnit \u00een tumorile considerate ca fiind cu risc redus, sau \u00een cele cu risc crescut. Acest subiect de cercetare poate fi elucidat prin \u00eencorporarea tehnicilor de investiga\u021bie a carcinomului bazocelular ce sunt disponibile, invazive (analiza morfopatologic\u0103) \u0219i non-invazive (dermatoscopie, tomografia de coeren\u021b\u0103 optic\u0103 \u0219i microscopia confocal\u0103 de reflexie).<\/p>\n
Innovation through discovery \u2013 the basal cell carcinoma\u2019s clefting artifact and its in vivoprofile<\/span><\/p>\nElena Niculet1,2, Florin Bujoreanu2,3, Diana Sabina Radaschin2,3,4, Andra Gherghi2,3, Simona Ioana Silion3, Alin Laurentiu Tatu2,4,5<\/span><\/p>\n1Department of Morphological and Functional Sciences, Faculty of Medicine and Pharmacy, “Dun\u0103rea de Jos” University, Gala\u021bi, Rom\u00e2nia
2 Integrated Multidisciplinary Center for Dermatological Interface Research – CIM-CID, “Dun\u0103rea de Jos” University, Gala\u021bi, Rom\u00e2nia
3Department of Dermatology and Venereology, Clinical Hospital for Infectious Diseases “St. Cuvioasa Parascheva”, Gala\u021bi, Rom\u00e2nia
4Clinical Medical Department, Faculty of Medicine and Pharmacy, “Dun\u0103rea de Jos” University, Gala\u021bi, Rom\u00e2nia<\/p>\n
Keywords: basal cell carcinoma, structural features of aggression, cleft, clefting, optical coherence tomography, reflectance confocalmicroscopy, morfopathology<\/p>\n
As a well-documented malignant tumor, the basal cell carcinoma (and inherently the patients) benefits from an almost complete record of its clinical features, histopathological aspects, prognostic factors and treatment modalities. Research has shed light on new types of in vivo investigative methods, namely optical coherence tomography and reflectance confocal microscopy, which help in identifying other facets of this tumor. The aforementioned techniques make possible the in vivo examination of a basal cell carcinoma\u2019s depth of invasion, its tumor mass margins preceding the surgical excision, its non-invasive treatment response, along with the vascular profile of such tumor. By using the optical coherence tomography and reflectance confocal microscopy analysis techniques, a key aspect has been found regarding basal cell carcinoma \u2013 its cleft or clefting artifact (being found in-between the tumor nodules\/chords and the encompassing tumor stroma, thought about as being a pathology laboratory processing artifact), is actually a structural trait which can be found in vivo, having apparent mucin material. Of interest would be whether this tumor aspect can be a predictive factor in the patient\u2019s post-treatment evolution and whether it can be found more frequently in tumors considered as having a low-risk behavior, or in those having a more aggressive one. This research query can be solved by incorporating the investigative methods at hand, both invasive ones (histopathology, with thenewly, simplified proposed classification) and those that are non-invasive (dermatoscopy, optical, coherence tomography and reflectance confocal microscopy), which are used in examining basal cell carcinomas.<\/p>\n
Scurt CV<\/span><\/p>\nN\u0103scut \u00een 1968, urmeaz\u0103 etapele \u015fcolariz\u0103rii fiind absolvent al Liceului de Matematic\u0103-Fizic\u0103 \u201dVasile Alecsandri\u201d Gala\u0163i \u015fi olimpic na\u0163ional la matematic\u0103. Dup\u0103 stagiul militar, studiaz\u0103 apoi la Universitatea de Medicin\u0103 \u015fi Farmacie \u201dCarol Davila\u201d din Bucure\u015fti. Se formeaz\u0103 ca dermatolog \u00een Spitalul Clinic \u201dColentina\u201d sub bagheta Prof. Dr. Forsea, Prof. dr. Giurc\u0103neanu \u015fi a dr. Smaranda Iosif. Ob\u0163ine primul loc la examenul de medic specialist sus\u0163inut la Bucure\u015fti \u015fi de asemenea primul loc la examenul de medic primar sus\u0163inut la Timi\u015foara.
Ob\u0163ine prin concurs postul de medic dermato venerolog la Spitalul de Urgen\u0163\u0103 \u201dSf. Apostol Andrei\u201d din Gala\u0163i \u015fi lucreaz\u0103 \u00een paralel \u00een sistem privat. Se implic\u0103 \u00een dezvoltarea tematicilor \u015fi programelor noii Facult\u0103\u0163i de Medicin\u0103 \u015fi Farmacie din cadrul Universit\u0103\u0163ii \u201dDun\u0103rea de Jos\u201d din Gala\u0163i unde sus\u0163ine ini\u0163ial cursuri \u015fi lucr\u0103ri ca asociat, apoi din 2011 ca titular angajat.
\u00cen 2017 sus\u0163ine Teza de Abilitare \u015fi tot din acel an devine Profesor universitar abilitat al Facult\u0103\u0163ii de Medicin\u0103 \u015fi Farmacie din Gala\u0163i. Din 2018 este conduc\u0103tor de doctorat av\u00e2nd \u00een coordonare 3 doctoranzi \u015fi sus\u0163ine cursuri de studii doctorale avansate \u00een cadrul \u015ecolii Doctorale de \u015etiin\u0163e Fundamentale \u015fi Inginere\u015fti. A publicat numeroase articole de specialitate in extenso indexate ISI, BDI realiz\u00e2nd un indice Hirsch 7 la \u00eenceputul lui 2019.
Este membru al EADV, AAD, EHRS, ISD, ESDR, ESPD \u015fi al Societ\u0103\u0163ii Japoneze de Dermatologie Investigativ\u0103. Este Board Director \u015fi Vicepre\u015fedinte al Societ\u0103\u0163ii Interna\u0163ionale de Dermatologie\u2013ISD.
Domeniile de cercetare de interes sunt reprezentate de Demodex Folliculorum, microbiomul cutanat asociat\/independent de Demodex, Dermoscopia\/Entomodermoscopia, Rozacee, inclusiv cea indus\u0103 steroidian, vitiligo, alter\u0103ri cutanate asociate tulbur\u0103rilor endocrine, prurit, durere cutanat\u0103, alter\u0103ri pilare.<\/p>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.19.4″ background_color=”rgba(240,98,42,0.19)” background_image=”https:\/\/pdi.ro\/2023\/wp-content\/uploads\/2022\/12\/PDI2023_header__-scaled.jpg” background_blend=”multiply” custom_padding=”54px|0px|0|0px|false|false” top_divider_style=”waves2″ top_divider_color=”#ffffff” top_divider_height=”155px” top_divider_height_tablet=”” top_divider_height_phone=”97px” top_divider_height_last_edited=”on|desktop” bottom_divider_style=”waves2″ bottom_divider_color=”#F0622A” bottom_divider_flip=”vertical” bottom_divider_height_tablet=”” bottom_divider_height_phone=”59px” bottom_divider_height_last_edited=”on|desktop” global_module=”9177″ saved_tabs=”all” global_colors_info=”{}”][et_pb_row column_structure=”3_5,2_5″ _builder_version=”4.19.4″ custom_padding=”100px|0px|69px|0px|false|false” global_colors_info=”{}”][et_pb_column type=”3_5″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text disabled_on=”off|off|off” _builder_version=”4.20.2″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” text_line_height=”1.2em” header_font=”||||||||” background_layout=”dark” text_font_size_tablet=”” text_font_size_phone=”” text_font_size_last_edited=”on|desktop” global_colors_info=”{}”]<\/p>\n
Contacteaz\u0103 operatorul PDI 2023<\/p>\n
[\/et_pb_text][et_pb_contact_form email=”contact@pdi.ro” submit_button_text=”Trimite mesajul” disabled_on=”off|off|off” _builder_version=”4.20.2″ _unique_id=”794aaef5-e005-432a-99fb-9ca53e06d67b” title_font=”||||||||” custom_button=”on” button_text_color=”#F0622A” global_colors_info=”{}”][et_pb_contact_field field_id=”Name” field_title=”Nume” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Email” field_title=”Adresa de e-mail” field_type=”email” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Message” field_title=”Mesajul dvs.” field_type=”text” fullwidth_field=”on” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][\/et_pb_contact_form][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.19.4″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” global_colors_info=”{}”]<\/p>\n
Operatorul PDI 2023<\/p>\n
[\/et_pb_text][et_pb_text _builder_version=”4.16″ text_font=”||||||||” global_colors_info=”{}”]<\/p>\n
![\"\"](\"https:\/\/pdi.ro\/2023\/2022\/wp-content\/uploads\/2020\/02\/eventer_logo_150px.png\")
<\/span><\/p>\n<\/span><\/p>\n<\/span><\/p>\nAdresa: Str. A. Panu nr. 13, Iasi<\/span>
Tel.: 0332.40.88.00-05<\/span>
E-mail: contact@pdi.ro<\/a>
<\/span>Website:\u00a0<\/span>www.eventernet.ro<\/a><\/p>\n[\/et_pb_text][et_pb_text disabled_on=”off|off|off” _builder_version=”4.20.2″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” locked=”off” global_colors_info=”{}”]<\/p>\n
Parteneri Media<\/p>\n
[\/et_pb_text][et_pb_slider disabled_on=”off|off|off” _builder_version=”4.20.2″ _module_preset=”default” position_origin_r=”bottom_left” width=”200px” max_width=”200px” content_width=”200px” content_max_width=”200px” min_height=”100px” height=”100px” max_height=”100px” custom_margin=”0px||0px||false|false” custom_padding=”0px||0px||false|false” auto=”on” auto_speed=”3000″ global_colors_info=”{}”][et_pb_slide _builder_version=”4.20.2″ _module_preset=”default” background_enable_color=”off” background_image=”https:\/\/pdi.ro\/2023\/2022\/wp-content\/uploads\/2022\/05\/timpul_.jpg” background_enable_image=”on” background_size=”initial” custom_padding=”0px||0px||false|false” link_option_url=”#” link_option_url_new_window=”on” global_colors_info=”{}” sticky_transition=”on”][\/et_pb_slide][et_pb_slide _builder_version=”4.20.2″ _module_preset=”default” background_enable_color=”off” background_image=”https:\/\/pdi.ro\/2023\/2022\/wp-content\/uploads\/2022\/05\/medical-market_.jpg” background_enable_image=”on” background_size=”initial” custom_padding=”0px||0px||false|false” link_option_url=”https:\/\/issuu.com\/finwatch\/docs\/dermato?fr=sYWIzMjQ1MDUxNTY” link_option_url_new_window=”on” global_colors_info=”{}” sticky_transition=”on”][\/et_pb_slide][\/et_pb_slider][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"
Prof. Dr. Tatu Alin Lauren\u021biuFacultatea de Medicin\u0103 \u015fi Farmacie din Gala\u0163i, Rom\u00e2niaProfilul in vivo prin Microscopie Confocala de Reflectanta si Tomografie in Coerenta optica al unei tr\u0103s\u0103turi particulare ce caracterizeaz\u0103 carcinomul bazocelular \u2013 separarea tumor\u0103-strom\u0103 Autori: Elena Niculet1,2, Florin Bujoreanu2,3, Diana Sabina Radaschin2,3,4, Andra Gherghi2,3, Simona Ioana Silion3, Alin Laurentiu Tatu2,4,5 1Departmentul de \u0218tiin\u021be Morfologice […]<\/p>\n","protected":false},"author":2,"featured_media":11458,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[12],"tags":[],"class_list":["post-8381","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lectori"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/posts\/8381","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/comments?post=8381"}],"version-history":[{"count":16,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/posts\/8381\/revisions"}],"predecessor-version":[{"id":13079,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/posts\/8381\/revisions\/13079"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/media\/11458"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/media?parent=8381"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/categories?post=8381"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/tags?post=8381"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Prof. Dr. Tatu Alin Lauren\u021biu<\/span><\/strong>
Facultatea de Medicin\u0103 \u015fi Farmacie din Gala\u0163i, Rom\u00e2nia<\/span><\/strong><\/h4>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.16″ global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.20.4″ hover_enabled=”0″ global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n
Profilul in vivo prin Microscopie Confocala de Reflectanta si Tomografie in Coerenta optica al unei tr\u0103s\u0103turi particulare ce caracterizeaz\u0103 carcinomul bazocelular \u2013 separarea tumor\u0103-strom\u0103<\/span><\/p>\nAutori: Elena Niculet1,2, Florin Bujoreanu2,3, Diana Sabina Radaschin2,3,4, Andra Gherghi2,3, Simona Ioana Silion3, Alin Laurentiu Tatu2,4,5
<\/span><\/p>\n1Departmentul de \u0218tiin\u021be Morfologice \u0219i Func\u021bionale, Facultatea de Medicin\u0103 \u0219i Farmacie, Universitatea \u201cDun\u0103rea de Jos\u201d, Gala\u021bi, Rom\u00e2nia
2Centrul Integrat Multidisciplinar de Cercetare de Interfata Dermatologica – CIM-CID, Universitatea \u201cDun\u0103rea de Jos\u201d, Gala\u021bi, Rom\u00e2nia
3Departamentul de Dermatologie \u0219i Venerologie, Spitalul Clinic de Boli Infec\u021bioase “Sf. Cuvioasa Parascheva”, Gala\u021bi, Rom\u00e2nia
4Departamentul Clinic Medical, Facultatea de Medicin\u0103 \u0219i Farmacie, Universitatea \u201cDun\u0103rea de Jos\u201d, Gala\u021bi, Rom\u00e2nia<\/p>\n
Cuvinte cheie: carcinomul bazocelular, tr\u0103s\u0103turi structurale de agresivitate, fant\u0103, separa\u021bie, tomografia de coeren\u021b\u0103 optic\u0103, microscopia confocal\u0103 de reflexie, morfopatologie<\/p>\n
Carcinomul bazocelular este o tumor\u0103 malign\u0103 cutanat\u0103 bine documentat\u0103 \u00een ceea ce prive\u0219te tr\u0103s\u0103turile clinice, aspectele morfopatologice, factorii de prognostic \u0219i op\u021biunile terapeutice. Cercetarea medical\u0103 contemporan\u0103 beneficiaz\u0103 de modalit\u0103\u021bi inovative de diagnostic \u0219i investiga\u021bie a acestor tumori, utiliz\u00e2nd tomografia de coeren\u021b\u0103 optic\u0103 \u0219i microscopia confocal\u0103 de reflexie \u00een scopul identific\u0103rii unor fa\u021bete noi ale carcinomului bazocelular. Datorit\u0103 acestor dou\u0103 tehnici este posibil\u0103 examinarea in vivo a profunzimii invaziei, a marginilor prolifer\u0103rii tumorale anterior exciziei chirurgicale a acesteia, r\u0103spunsul tumorii la tratamentul non-invaziv, precum \u0219i profilul vascular ce caracterizeaza tumora. De asemenea, prin utilizarea acestor dou\u0103 tehnici de examinare s-a descoperit un aspect particular al carcinomului bazocelular: fanta sau artefactul de separare dintre cuiburile tumorale \u0219i stroma \u00eenconjur\u0103toare, despre care s-a crezut ca este un artefact, un rezultat al proces\u0103rii tisulare din laboratorul de morfopatologie, este de fapt o structur\u0103 ce poate fi evaulat\u0103 in vivo, aparent cu identificarea unui material la acest nivel (posibil, mucn\u0103). Este esen\u021bial\u0103 stabilirea rolului acestui aspect structural ca factor prognostic pentru pacient, rolul pe care \u00eel joac\u0103 \u00een evolu\u021bia post-terapeutic\u0103 non-invaziv\u0103 \u0219i dac\u0103 acesta este frecvent \u00eent\u00e2lnit \u00een tumorile considerate ca fiind cu risc redus, sau \u00een cele cu risc crescut. Acest subiect de cercetare poate fi elucidat prin \u00eencorporarea tehnicilor de investiga\u021bie a carcinomului bazocelular ce sunt disponibile, invazive (analiza morfopatologic\u0103) \u0219i non-invazive (dermatoscopie, tomografia de coeren\u021b\u0103 optic\u0103 \u0219i microscopia confocal\u0103 de reflexie).<\/p>\n
Innovation through discovery \u2013 the basal cell carcinoma\u2019s clefting artifact and its in vivoprofile<\/span><\/p>\nElena Niculet1,2, Florin Bujoreanu2,3, Diana Sabina Radaschin2,3,4, Andra Gherghi2,3, Simona Ioana Silion3, Alin Laurentiu Tatu2,4,5<\/span><\/p>\n1Department of Morphological and Functional Sciences, Faculty of Medicine and Pharmacy, “Dun\u0103rea de Jos” University, Gala\u021bi, Rom\u00e2nia
2 Integrated Multidisciplinary Center for Dermatological Interface Research – CIM-CID, “Dun\u0103rea de Jos” University, Gala\u021bi, Rom\u00e2nia
3Department of Dermatology and Venereology, Clinical Hospital for Infectious Diseases “St. Cuvioasa Parascheva”, Gala\u021bi, Rom\u00e2nia
4Clinical Medical Department, Faculty of Medicine and Pharmacy, “Dun\u0103rea de Jos” University, Gala\u021bi, Rom\u00e2nia<\/p>\n
Keywords: basal cell carcinoma, structural features of aggression, cleft, clefting, optical coherence tomography, reflectance confocalmicroscopy, morfopathology<\/p>\n
As a well-documented malignant tumor, the basal cell carcinoma (and inherently the patients) benefits from an almost complete record of its clinical features, histopathological aspects, prognostic factors and treatment modalities. Research has shed light on new types of in vivo investigative methods, namely optical coherence tomography and reflectance confocal microscopy, which help in identifying other facets of this tumor. The aforementioned techniques make possible the in vivo examination of a basal cell carcinoma\u2019s depth of invasion, its tumor mass margins preceding the surgical excision, its non-invasive treatment response, along with the vascular profile of such tumor. By using the optical coherence tomography and reflectance confocal microscopy analysis techniques, a key aspect has been found regarding basal cell carcinoma \u2013 its cleft or clefting artifact (being found in-between the tumor nodules\/chords and the encompassing tumor stroma, thought about as being a pathology laboratory processing artifact), is actually a structural trait which can be found in vivo, having apparent mucin material. Of interest would be whether this tumor aspect can be a predictive factor in the patient\u2019s post-treatment evolution and whether it can be found more frequently in tumors considered as having a low-risk behavior, or in those having a more aggressive one. This research query can be solved by incorporating the investigative methods at hand, both invasive ones (histopathology, with thenewly, simplified proposed classification) and those that are non-invasive (dermatoscopy, optical, coherence tomography and reflectance confocal microscopy), which are used in examining basal cell carcinomas.<\/p>\n
Scurt CV<\/span><\/p>\nN\u0103scut \u00een 1968, urmeaz\u0103 etapele \u015fcolariz\u0103rii fiind absolvent al Liceului de Matematic\u0103-Fizic\u0103 \u201dVasile Alecsandri\u201d Gala\u0163i \u015fi olimpic na\u0163ional la matematic\u0103. Dup\u0103 stagiul militar, studiaz\u0103 apoi la Universitatea de Medicin\u0103 \u015fi Farmacie \u201dCarol Davila\u201d din Bucure\u015fti. Se formeaz\u0103 ca dermatolog \u00een Spitalul Clinic \u201dColentina\u201d sub bagheta Prof. Dr. Forsea, Prof. dr. Giurc\u0103neanu \u015fi a dr. Smaranda Iosif. Ob\u0163ine primul loc la examenul de medic specialist sus\u0163inut la Bucure\u015fti \u015fi de asemenea primul loc la examenul de medic primar sus\u0163inut la Timi\u015foara.
Ob\u0163ine prin concurs postul de medic dermato venerolog la Spitalul de Urgen\u0163\u0103 \u201dSf. Apostol Andrei\u201d din Gala\u0163i \u015fi lucreaz\u0103 \u00een paralel \u00een sistem privat. Se implic\u0103 \u00een dezvoltarea tematicilor \u015fi programelor noii Facult\u0103\u0163i de Medicin\u0103 \u015fi Farmacie din cadrul Universit\u0103\u0163ii \u201dDun\u0103rea de Jos\u201d din Gala\u0163i unde sus\u0163ine ini\u0163ial cursuri \u015fi lucr\u0103ri ca asociat, apoi din 2011 ca titular angajat.
\u00cen 2017 sus\u0163ine Teza de Abilitare \u015fi tot din acel an devine Profesor universitar abilitat al Facult\u0103\u0163ii de Medicin\u0103 \u015fi Farmacie din Gala\u0163i. Din 2018 este conduc\u0103tor de doctorat av\u00e2nd \u00een coordonare 3 doctoranzi \u015fi sus\u0163ine cursuri de studii doctorale avansate \u00een cadrul \u015ecolii Doctorale de \u015etiin\u0163e Fundamentale \u015fi Inginere\u015fti. A publicat numeroase articole de specialitate in extenso indexate ISI, BDI realiz\u00e2nd un indice Hirsch 7 la \u00eenceputul lui 2019.
Este membru al EADV, AAD, EHRS, ISD, ESDR, ESPD \u015fi al Societ\u0103\u0163ii Japoneze de Dermatologie Investigativ\u0103. Este Board Director \u015fi Vicepre\u015fedinte al Societ\u0103\u0163ii Interna\u0163ionale de Dermatologie\u2013ISD.
Domeniile de cercetare de interes sunt reprezentate de Demodex Folliculorum, microbiomul cutanat asociat\/independent de Demodex, Dermoscopia\/Entomodermoscopia, Rozacee, inclusiv cea indus\u0103 steroidian, vitiligo, alter\u0103ri cutanate asociate tulbur\u0103rilor endocrine, prurit, durere cutanat\u0103, alter\u0103ri pilare.<\/p>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.19.4″ background_color=”rgba(240,98,42,0.19)” background_image=”https:\/\/pdi.ro\/2023\/wp-content\/uploads\/2022\/12\/PDI2023_header__-scaled.jpg” background_blend=”multiply” custom_padding=”54px|0px|0|0px|false|false” top_divider_style=”waves2″ top_divider_color=”#ffffff” top_divider_height=”155px” top_divider_height_tablet=”” top_divider_height_phone=”97px” top_divider_height_last_edited=”on|desktop” bottom_divider_style=”waves2″ bottom_divider_color=”#F0622A” bottom_divider_flip=”vertical” bottom_divider_height_tablet=”” bottom_divider_height_phone=”59px” bottom_divider_height_last_edited=”on|desktop” global_module=”9177″ saved_tabs=”all” global_colors_info=”{}”][et_pb_row column_structure=”3_5,2_5″ _builder_version=”4.19.4″ custom_padding=”100px|0px|69px|0px|false|false” global_colors_info=”{}”][et_pb_column type=”3_5″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text disabled_on=”off|off|off” _builder_version=”4.20.2″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” text_line_height=”1.2em” header_font=”||||||||” background_layout=”dark” text_font_size_tablet=”” text_font_size_phone=”” text_font_size_last_edited=”on|desktop” global_colors_info=”{}”]<\/p>\n
Contacteaz\u0103 operatorul PDI 2023<\/p>\n
[\/et_pb_text][et_pb_contact_form email=”contact@pdi.ro” submit_button_text=”Trimite mesajul” disabled_on=”off|off|off” _builder_version=”4.20.2″ _unique_id=”794aaef5-e005-432a-99fb-9ca53e06d67b” title_font=”||||||||” custom_button=”on” button_text_color=”#F0622A” global_colors_info=”{}”][et_pb_contact_field field_id=”Name” field_title=”Nume” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Email” field_title=”Adresa de e-mail” field_type=”email” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Message” field_title=”Mesajul dvs.” field_type=”text” fullwidth_field=”on” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][\/et_pb_contact_form][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.19.4″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” global_colors_info=”{}”]<\/p>\n
Operatorul PDI 2023<\/p>\n
[\/et_pb_text][et_pb_text _builder_version=”4.16″ text_font=”||||||||” global_colors_info=”{}”]<\/p>\n
<\/span><\/p>\n<\/span><\/p>\n<\/span><\/p>\nAdresa: Str. A. Panu nr. 13, Iasi<\/span>
Tel.: 0332.40.88.00-05<\/span>
E-mail: contact@pdi.ro<\/a>
<\/span>Website:\u00a0<\/span>www.eventernet.ro<\/a><\/p>\n[\/et_pb_text][et_pb_text disabled_on=”off|off|off” _builder_version=”4.20.2″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” locked=”off” global_colors_info=”{}”]<\/p>\n
Parteneri Media<\/p>\n
[\/et_pb_text][et_pb_slider disabled_on=”off|off|off” _builder_version=”4.20.2″ _module_preset=”default” position_origin_r=”bottom_left” width=”200px” max_width=”200px” content_width=”200px” content_max_width=”200px” min_height=”100px” height=”100px” max_height=”100px” custom_margin=”0px||0px||false|false” custom_padding=”0px||0px||false|false” auto=”on” auto_speed=”3000″ global_colors_info=”{}”][et_pb_slide _builder_version=”4.20.2″ _module_preset=”default” background_enable_color=”off” background_image=”https:\/\/pdi.ro\/2023\/2022\/wp-content\/uploads\/2022\/05\/timpul_.jpg” background_enable_image=”on” background_size=”initial” custom_padding=”0px||0px||false|false” link_option_url=”#” link_option_url_new_window=”on” global_colors_info=”{}” sticky_transition=”on”][\/et_pb_slide][et_pb_slide _builder_version=”4.20.2″ _module_preset=”default” background_enable_color=”off” background_image=”https:\/\/pdi.ro\/2023\/2022\/wp-content\/uploads\/2022\/05\/medical-market_.jpg” background_enable_image=”on” background_size=”initial” custom_padding=”0px||0px||false|false” link_option_url=”https:\/\/issuu.com\/finwatch\/docs\/dermato?fr=sYWIzMjQ1MDUxNTY” link_option_url_new_window=”on” global_colors_info=”{}” sticky_transition=”on”][\/et_pb_slide][\/et_pb_slider][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"
Prof. Dr. Tatu Alin Lauren\u021biuFacultatea de Medicin\u0103 \u015fi Farmacie din Gala\u0163i, Rom\u00e2niaProfilul in vivo prin Microscopie Confocala de Reflectanta si Tomografie in Coerenta optica al unei tr\u0103s\u0103turi particulare ce caracterizeaz\u0103 carcinomul bazocelular \u2013 separarea tumor\u0103-strom\u0103 Autori: Elena Niculet1,2, Florin Bujoreanu2,3, Diana Sabina Radaschin2,3,4, Andra Gherghi2,3, Simona Ioana Silion3, Alin Laurentiu Tatu2,4,5 1Departmentul de \u0218tiin\u021be Morfologice […]<\/p>\n","protected":false},"author":2,"featured_media":11458,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[12],"tags":[],"class_list":["post-8381","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lectori"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/posts\/8381","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/comments?post=8381"}],"version-history":[{"count":16,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/posts\/8381\/revisions"}],"predecessor-version":[{"id":13079,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/posts\/8381\/revisions\/13079"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/media\/11458"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/media?parent=8381"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/categories?post=8381"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/tags?post=8381"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Autori: Elena Niculet1,2, Florin Bujoreanu2,3, Diana Sabina Radaschin2,3,4, Andra Gherghi2,3, Simona Ioana Silion3, Alin Laurentiu Tatu2,4,5 1Departmentul de \u0218tiin\u021be Morfologice \u0219i Func\u021bionale, Facultatea de Medicin\u0103 \u0219i Farmacie, Universitatea \u201cDun\u0103rea de Jos\u201d, Gala\u021bi, Rom\u00e2nia Cuvinte cheie: carcinomul bazocelular, tr\u0103s\u0103turi structurale de agresivitate, fant\u0103, separa\u021bie, tomografia de coeren\u021b\u0103 optic\u0103, microscopia confocal\u0103 de reflexie, morfopatologie<\/p>\n Carcinomul bazocelular este o tumor\u0103 malign\u0103 cutanat\u0103 bine documentat\u0103 \u00een ceea ce prive\u0219te tr\u0103s\u0103turile clinice, aspectele morfopatologice, factorii de prognostic \u0219i op\u021biunile terapeutice. Cercetarea medical\u0103 contemporan\u0103 beneficiaz\u0103 de modalit\u0103\u021bi inovative de diagnostic \u0219i investiga\u021bie a acestor tumori, utiliz\u00e2nd tomografia de coeren\u021b\u0103 optic\u0103 \u0219i microscopia confocal\u0103 de reflexie \u00een scopul identific\u0103rii unor fa\u021bete noi ale carcinomului bazocelular. Datorit\u0103 acestor dou\u0103 tehnici este posibil\u0103 examinarea in vivo a profunzimii invaziei, a marginilor prolifer\u0103rii tumorale anterior exciziei chirurgicale a acesteia, r\u0103spunsul tumorii la tratamentul non-invaziv, precum \u0219i profilul vascular ce caracterizeaza tumora. De asemenea, prin utilizarea acestor dou\u0103 tehnici de examinare s-a descoperit un aspect particular al carcinomului bazocelular: fanta sau artefactul de separare dintre cuiburile tumorale \u0219i stroma \u00eenconjur\u0103toare, despre care s-a crezut ca este un artefact, un rezultat al proces\u0103rii tisulare din laboratorul de morfopatologie, este de fapt o structur\u0103 ce poate fi evaulat\u0103 in vivo, aparent cu identificarea unui material la acest nivel (posibil, mucn\u0103). Este esen\u021bial\u0103 stabilirea rolului acestui aspect structural ca factor prognostic pentru pacient, rolul pe care \u00eel joac\u0103 \u00een evolu\u021bia post-terapeutic\u0103 non-invaziv\u0103 \u0219i dac\u0103 acesta este frecvent \u00eent\u00e2lnit \u00een tumorile considerate ca fiind cu risc redus, sau \u00een cele cu risc crescut. Acest subiect de cercetare poate fi elucidat prin \u00eencorporarea tehnicilor de investiga\u021bie a carcinomului bazocelular ce sunt disponibile, invazive (analiza morfopatologic\u0103) \u0219i non-invazive (dermatoscopie, tomografia de coeren\u021b\u0103 optic\u0103 \u0219i microscopia confocal\u0103 de reflexie).<\/p>\n Innovation through discovery \u2013 the basal cell carcinoma\u2019s clefting artifact and its in vivoprofile<\/span><\/p>\n Elena Niculet1,2, Florin Bujoreanu2,3, Diana Sabina Radaschin2,3,4, Andra Gherghi2,3, Simona Ioana Silion3, Alin Laurentiu Tatu2,4,5<\/span><\/p>\n 1Department of Morphological and Functional Sciences, Faculty of Medicine and Pharmacy, “Dun\u0103rea de Jos” University, Gala\u021bi, Rom\u00e2nia Keywords: basal cell carcinoma, structural features of aggression, cleft, clefting, optical coherence tomography, reflectance confocalmicroscopy, morfopathology<\/p>\n As a well-documented malignant tumor, the basal cell carcinoma (and inherently the patients) benefits from an almost complete record of its clinical features, histopathological aspects, prognostic factors and treatment modalities. Research has shed light on new types of in vivo investigative methods, namely optical coherence tomography and reflectance confocal microscopy, which help in identifying other facets of this tumor. The aforementioned techniques make possible the in vivo examination of a basal cell carcinoma\u2019s depth of invasion, its tumor mass margins preceding the surgical excision, its non-invasive treatment response, along with the vascular profile of such tumor. By using the optical coherence tomography and reflectance confocal microscopy analysis techniques, a key aspect has been found regarding basal cell carcinoma \u2013 its cleft or clefting artifact (being found in-between the tumor nodules\/chords and the encompassing tumor stroma, thought about as being a pathology laboratory processing artifact), is actually a structural trait which can be found in vivo, having apparent mucin material. Of interest would be whether this tumor aspect can be a predictive factor in the patient\u2019s post-treatment evolution and whether it can be found more frequently in tumors considered as having a low-risk behavior, or in those having a more aggressive one. This research query can be solved by incorporating the investigative methods at hand, both invasive ones (histopathology, with thenewly, simplified proposed classification) and those that are non-invasive (dermatoscopy, optical, coherence tomography and reflectance confocal microscopy), which are used in examining basal cell carcinomas.<\/p>\n Scurt CV<\/span><\/p>\n N\u0103scut \u00een 1968, urmeaz\u0103 etapele \u015fcolariz\u0103rii fiind absolvent al Liceului de Matematic\u0103-Fizic\u0103 \u201dVasile Alecsandri\u201d Gala\u0163i \u015fi olimpic na\u0163ional la matematic\u0103. Dup\u0103 stagiul militar, studiaz\u0103 apoi la Universitatea de Medicin\u0103 \u015fi Farmacie \u201dCarol Davila\u201d din Bucure\u015fti. Se formeaz\u0103 ca dermatolog \u00een Spitalul Clinic \u201dColentina\u201d sub bagheta Prof. Dr. Forsea, Prof. dr. Giurc\u0103neanu \u015fi a dr. Smaranda Iosif. Ob\u0163ine primul loc la examenul de medic specialist sus\u0163inut la Bucure\u015fti \u015fi de asemenea primul loc la examenul de medic primar sus\u0163inut la Timi\u015foara. [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.19.4″ background_color=”rgba(240,98,42,0.19)” background_image=”https:\/\/pdi.ro\/2023\/wp-content\/uploads\/2022\/12\/PDI2023_header__-scaled.jpg” background_blend=”multiply” custom_padding=”54px|0px|0|0px|false|false” top_divider_style=”waves2″ top_divider_color=”#ffffff” top_divider_height=”155px” top_divider_height_tablet=”” top_divider_height_phone=”97px” top_divider_height_last_edited=”on|desktop” bottom_divider_style=”waves2″ bottom_divider_color=”#F0622A” bottom_divider_flip=”vertical” bottom_divider_height_tablet=”” bottom_divider_height_phone=”59px” bottom_divider_height_last_edited=”on|desktop” global_module=”9177″ saved_tabs=”all” global_colors_info=”{}”][et_pb_row column_structure=”3_5,2_5″ _builder_version=”4.19.4″ custom_padding=”100px|0px|69px|0px|false|false” global_colors_info=”{}”][et_pb_column type=”3_5″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text disabled_on=”off|off|off” _builder_version=”4.20.2″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” text_line_height=”1.2em” header_font=”||||||||” background_layout=”dark” text_font_size_tablet=”” text_font_size_phone=”” text_font_size_last_edited=”on|desktop” global_colors_info=”{}”]<\/p>\n Contacteaz\u0103 operatorul PDI 2023<\/p>\n [\/et_pb_text][et_pb_contact_form email=”contact@pdi.ro” submit_button_text=”Trimite mesajul” disabled_on=”off|off|off” _builder_version=”4.20.2″ _unique_id=”794aaef5-e005-432a-99fb-9ca53e06d67b” title_font=”||||||||” custom_button=”on” button_text_color=”#F0622A” global_colors_info=”{}”][et_pb_contact_field field_id=”Name” field_title=”Nume” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Email” field_title=”Adresa de e-mail” field_type=”email” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Message” field_title=”Mesajul dvs.” field_type=”text” fullwidth_field=”on” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][\/et_pb_contact_form][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.19.4″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” global_colors_info=”{}”]<\/p>\n Operatorul PDI 2023<\/p>\n [\/et_pb_text][et_pb_text _builder_version=”4.16″ text_font=”||||||||” global_colors_info=”{}”]<\/p>\n <\/span><\/p>\n <\/span><\/p>\n Adresa: Str. A. Panu nr. 13, Iasi<\/span> [\/et_pb_text][et_pb_text disabled_on=”off|off|off” _builder_version=”4.20.2″ text_font=”Kaushan Script||||||||” text_text_color=”#f0622a” text_font_size=”30px” header_font=”||||||||” background_layout=”dark” locked=”off” global_colors_info=”{}”]<\/p>\n Parteneri Media<\/p>\n [\/et_pb_text][et_pb_slider disabled_on=”off|off|off” _builder_version=”4.20.2″ _module_preset=”default” position_origin_r=”bottom_left” width=”200px” max_width=”200px” content_width=”200px” content_max_width=”200px” min_height=”100px” height=”100px” max_height=”100px” custom_margin=”0px||0px||false|false” custom_padding=”0px||0px||false|false” auto=”on” auto_speed=”3000″ global_colors_info=”{}”][et_pb_slide _builder_version=”4.20.2″ _module_preset=”default” background_enable_color=”off” background_image=”https:\/\/pdi.ro\/2023\/2022\/wp-content\/uploads\/2022\/05\/timpul_.jpg” background_enable_image=”on” background_size=”initial” custom_padding=”0px||0px||false|false” link_option_url=”#” link_option_url_new_window=”on” global_colors_info=”{}” sticky_transition=”on”][\/et_pb_slide][et_pb_slide _builder_version=”4.20.2″ _module_preset=”default” background_enable_color=”off” background_image=”https:\/\/pdi.ro\/2023\/2022\/wp-content\/uploads\/2022\/05\/medical-market_.jpg” background_enable_image=”on” background_size=”initial” custom_padding=”0px||0px||false|false” link_option_url=”https:\/\/issuu.com\/finwatch\/docs\/dermato?fr=sYWIzMjQ1MDUxNTY” link_option_url_new_window=”on” global_colors_info=”{}” sticky_transition=”on”][\/et_pb_slide][\/et_pb_slider][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" Prof. Dr. Tatu Alin Lauren\u021biuFacultatea de Medicin\u0103 \u015fi Farmacie din Gala\u0163i, Rom\u00e2niaProfilul in vivo prin Microscopie Confocala de Reflectanta si Tomografie in Coerenta optica al unei tr\u0103s\u0103turi particulare ce caracterizeaz\u0103 carcinomul bazocelular \u2013 separarea tumor\u0103-strom\u0103 Autori: Elena Niculet1,2, Florin Bujoreanu2,3, Diana Sabina Radaschin2,3,4, Andra Gherghi2,3, Simona Ioana Silion3, Alin Laurentiu Tatu2,4,5 1Departmentul de \u0218tiin\u021be Morfologice […]<\/p>\n","protected":false},"author":2,"featured_media":11458,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[12],"tags":[],"class_list":["post-8381","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lectori"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/posts\/8381","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/comments?post=8381"}],"version-history":[{"count":16,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/posts\/8381\/revisions"}],"predecessor-version":[{"id":13079,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/posts\/8381\/revisions\/13079"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/media\/11458"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/media?parent=8381"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/categories?post=8381"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/tags?post=8381"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
<\/span><\/p>\n
2Centrul Integrat Multidisciplinar de Cercetare de Interfata Dermatologica – CIM-CID, Universitatea \u201cDun\u0103rea de Jos\u201d, Gala\u021bi, Rom\u00e2nia
3Departamentul de Dermatologie \u0219i Venerologie, Spitalul Clinic de Boli Infec\u021bioase “Sf. Cuvioasa Parascheva”, Gala\u021bi, Rom\u00e2nia
4Departamentul Clinic Medical, Facultatea de Medicin\u0103 \u0219i Farmacie, Universitatea \u201cDun\u0103rea de Jos\u201d, Gala\u021bi, Rom\u00e2nia<\/p>\n
2 Integrated Multidisciplinary Center for Dermatological Interface Research – CIM-CID, “Dun\u0103rea de Jos” University, Gala\u021bi, Rom\u00e2nia
3Department of Dermatology and Venereology, Clinical Hospital for Infectious Diseases “St. Cuvioasa Parascheva”, Gala\u021bi, Rom\u00e2nia
4Clinical Medical Department, Faculty of Medicine and Pharmacy, “Dun\u0103rea de Jos” University, Gala\u021bi, Rom\u00e2nia<\/p>\n
Ob\u0163ine prin concurs postul de medic dermato venerolog la Spitalul de Urgen\u0163\u0103 \u201dSf. Apostol Andrei\u201d din Gala\u0163i \u015fi lucreaz\u0103 \u00een paralel \u00een sistem privat. Se implic\u0103 \u00een dezvoltarea tematicilor \u015fi programelor noii Facult\u0103\u0163i de Medicin\u0103 \u015fi Farmacie din cadrul Universit\u0103\u0163ii \u201dDun\u0103rea de Jos\u201d din Gala\u0163i unde sus\u0163ine ini\u0163ial cursuri \u015fi lucr\u0103ri ca asociat, apoi din 2011 ca titular angajat.
\u00cen 2017 sus\u0163ine Teza de Abilitare \u015fi tot din acel an devine Profesor universitar abilitat al Facult\u0103\u0163ii de Medicin\u0103 \u015fi Farmacie din Gala\u0163i. Din 2018 este conduc\u0103tor de doctorat av\u00e2nd \u00een coordonare 3 doctoranzi \u015fi sus\u0163ine cursuri de studii doctorale avansate \u00een cadrul \u015ecolii Doctorale de \u015etiin\u0163e Fundamentale \u015fi Inginere\u015fti. A publicat numeroase articole de specialitate in extenso indexate ISI, BDI realiz\u00e2nd un indice Hirsch 7 la \u00eenceputul lui 2019.
Este membru al EADV, AAD, EHRS, ISD, ESDR, ESPD \u015fi al Societ\u0103\u0163ii Japoneze de Dermatologie Investigativ\u0103. Este Board Director \u015fi Vicepre\u015fedinte al Societ\u0103\u0163ii Interna\u0163ionale de Dermatologie\u2013ISD.
Domeniile de cercetare de interes sunt reprezentate de Demodex Folliculorum, microbiomul cutanat asociat\/independent de Demodex, Dermoscopia\/Entomodermoscopia, Rozacee, inclusiv cea indus\u0103 steroidian, vitiligo, alter\u0103ri cutanate asociate tulbur\u0103rilor endocrine, prurit, durere cutanat\u0103, alter\u0103ri pilare.<\/p>\n<\/span><\/p>\n
Tel.: 0332.40.88.00-05<\/span>
E-mail: contact@pdi.ro<\/a>
<\/span>Website:\u00a0<\/span>www.eventernet.ro<\/a><\/p>\n