{"id":8539,"date":"2023-02-14T13:53:09","date_gmt":"2023-02-14T11:53:09","guid":{"rendered":"https:\/\/primaderma.ro\/?page_id=8539"},"modified":"2023-02-28T16:20:04","modified_gmt":"2023-02-28T14:20:04","slug":"conf-dr-branisteanu-daniel-constantin","status":"publish","type":"post","link":"https:\/\/pdi.ro\/2023\/conf-dr-branisteanu-daniel-constantin\/","title":{"rendered":"Conf. Univ. Dr. Br\u0103ni\u0219teanu Daniel Constantin"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; fullwidth=&#8221;on&#8221; disabled_on=&#8221;on|off|off&#8221; _builder_version=&#8221;4.19.4&#8243; custom_margin=&#8221;||&#8221; custom_padding=&#8221;15px||29px&#8221; top_divider_style=&#8221;waves2&#8243; top_divider_color=&#8221;#F0622A&#8221; top_divider_flip=&#8221;horizontal|vertical&#8221; bottom_divider_style=&#8221;waves2&#8243; bottom_divider_color=&#8221;#fcdedb&#8221; bottom_divider_height=&#8221;105px&#8221; bottom_divider_flip=&#8221;vertical&#8221; global_module=&#8221;9062&#8243; saved_tabs=&#8221;all&#8221; collapsed=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_fullwidth_header title=&#8221;@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF90aXRsZSIsInNldHRpbmdzIjp7ImJlZm9yZSI6IiIsImFmdGVyIjoiIn19@&#8221; disabled_on=&#8221;on|on|off&#8221; _builder_version=&#8221;4.19.4&#8243; _dynamic_attributes=&#8221;title&#8221; title_font=&#8221;Kaushan Script||||||||&#8221; title_text_align=&#8221;left&#8221; title_text_color=&#8221;#f0622a&#8221; title_font_size=&#8221;55px&#8221; content_font=&#8221;|600||on|||||&#8221; content_text_align=&#8221;center&#8221; content_text_color=&#8221;#686766&#8243; content_font_size=&#8221;15px&#8221; subhead_font=&#8221;||||||||&#8221; background_enable_color=&#8221;off&#8221; background_image=&#8221;https:\/\/pdi.ro\/2023\/wp-content\/uploads\/2022\/12\/PDI2023_header__-scaled.jpg&#8221; background_blend=&#8221;luminosity&#8221; background_layout=&#8221;light&#8221; custom_margin=&#8221;||-5px||false|false&#8221; custom_padding=&#8221;150px||150px||true|false&#8221; content_font_size_tablet=&#8221;&#8221; content_font_size_phone=&#8221;15px&#8221; content_font_size_last_edited=&#8221;on|desktop&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;2_5,3_5&#8243; _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;2_5&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_image src=&#8221;https:\/\/pdi.ro\/2023\/2022\/wp-content\/uploads\/2020\/02\/BranisteanuDaniel.png&#8221; title_text=&#8221;BranisteanuDaniel&#8221; align=&#8221;center&#8221; align_tablet=&#8221;center&#8221; align_phone=&#8221;&#8221; align_last_edited=&#8221;on|desktop&#8221; _builder_version=&#8221;4.16&#8243; max_width=&#8221;31%&#8221; border_radii=&#8221;on|100px|100px|100px|100px&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][et_pb_column type=&#8221;3_5&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.19.5&#8243; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h4><strong><span style=\"color: #ff6600;\"><\/span><\/strong><\/h4>\n<h4><strong><span style=\"color: #ff6600;\"><\/span><\/strong><\/h4>\n<h4><strong><span style=\"color: #ff6600;\"><\/span><\/strong><\/h4>\n<h4><strong><span style=\"color: #ff6600;\">Conf. Univ. Dr. Br\u0103ni\u0219teanu Daniel Constantin<\/span><\/strong><br \/><strong><span style=\"color: #ff6600;\">Universitatea de Medicin\u0103 \u0219i Farmacie \u201cGrigore T. Popa\u201d Ia\u0219i<br \/>Clinica &#8220;Retina Center&#8221;, Ia\u0219i\u00a0<\/span><\/strong><\/h4>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.19.5&#8243; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><!--<\/p>\n\n\n\n\n<p style=\"text-align: justify;\"><span style=\"color: #ff6600;\">Actualit\u0103\u021bi \u00een manifest\u0103rile oculare ale COVID-19\n\n\nAutori: D.C. Br\u0103ni\u015fteanu1,2, Anisia Iuliana Alexa1<\/span><span style=\"color: #ff6600;\"><\/span><\/p>\n\n\n\n\n<p style=\"text-align: justify;\">1. Disciplina Oftalmologie, Universitatea de Medicin\u0103 \u0219i Farmacie \u201cGrigore T.Popa\u201d, Ia\u0219i\n\n\n2. Clinica \u201cRetina Center\u201d, Ia\u0219i<\/p>\n\n\n\n\n<p>Cuvinte cheie: COVID-19, conjunctivit\u0103, uveit\u0103, ocluzii vasculare, neuropatie optic\u0103, vaccin<\/p>\n\n\n\n\n<p style=\"text-align: justify;\">COVID-19 este o patologie infec\u021bioas\u0103 cu poten\u021bial letal ce afecteaz\u0103 \u00een principal tractul respirator \u0219i care \u00ee\u0219i men\u021bine caracterul pandemic prin apari\u021bia constant\u0103 de noi tulpini ale coronavirusului SARS-CoV-2. Pe l\u00eeng\u0103 manifest\u0103rile respiratorii au fost raportate disfunc\u021bii multiorgan ce intereseaz\u0103 sistemul nervos central \u0219i periferic, miocardul, sistemul gastro-intestinal, tegumentul, sistemul endocrin \u0219i ochiul. Cu o inciden\u021b\u0103 estimat\u0103 \u00eentre 6 \u0219i 12%, infec\u021bia viral\u0103 concomitent\u0103 a suprafe\u021bei oculare, manifestat\u0103 prin conjunctivit\u0103 folicular\u0103, durere ocular\u0103, senza\u021bie de usc\u0103ciune, congestie \u0219i secre\u021bie a fost prima \u0219i cea mai comun\u0103 manifestare ocular\u0103 raportat\u0103. Inciden\u021ba acesteia cre\u0219te la copii \u0219i \u00een cazurile severe de COVID-19 la adult, c\u00e2nd se pot asocia keratopatia de expunere \u0219i leziunile corneene ulcerative la pacien\u021bii intubati sau cu masca respiratorie. Alte manifest\u0103ri rare raportate la nivelul segmentului anterior sunt sclerita nodular\u0103, conjunctivita membranoas\u0103 asociat\u0103 cu eritem multiform major \u0219i uveita anterioar\u0103. La nivelul segmentului posterior al ochiului COVID-19 cre\u0219te de aproape 9 ori riscul de apari\u021bie a microvasculopatiei caracterizat\u0103 prin hemoragii retiniene, exsudate v\u0103toase \u0219i rarefierea arborelui capilar. Au fost de asemenea descrise cazuri de neuroretinopatie macular\u0103 acut\u0103, ocluzii vasculare arteriale \u0219i venoase \u0219i corioretinit\u0103 multifocal\u0103. Paralizia musculaturii extraoculare, neuropatia optic\u0103 inflamatorie \u0219i cea ischemic\u0103 sunt atingeri neuro-oftalmologice consecin\u021b\u0103 a tulbur\u0103rilor ischemice \u0219i inflamatorii. Utilizarea diverselor vaccinuri COVID-19, a fost de asemenea asociat\u0103 cu manifest\u0103ri oculare diverse ce au variat ca severitate de la edem palpebral, leziuni echimotice sau purpurice palpebrale la tromboza venei oftalmice superioare, sdr. Tolosa-Hunt, ocluzii vasculare venoase \u0219i arteriale, neuroretinopatie acut\u0103 macular\u0103, maculopatie acut\u0103 paracentrala, uveit\u0103 anterioar\u0103, neuroretinit\u0103 \u0219i rejetul grefonului cornean.<\/p>\n\n\n\n\n<p style=\"text-align: justify;\"><span style=\"color: #ff6600;\">Ocular manifestations of COVID-19 \u2013 an update\n\n\nAuthors: D.C. Br\u0103ni\u015fteanu1,2, Anisia Iuliana Alexa1<\/span><span style=\"color: #ff6600;\"><\/span><\/p>\n\n\n\n\n<p style=\"text-align: justify;\">1. Ophthalmology Department, University of Medicine and Pharmacy \u201cGrigore T.Popa\u201d, Iasi\n\n\n2. \u201cRetina Center\u201d Eye Clinic, Iasi<\/p>\n\n\n\n\n<p>Keywords: COVID-19, conjunctivitis, uveitis, vascular occlusions, optic neuropathy, vaccine;<\/p>\n\n\n\n\n<p style=\"text-align: justify;\">COVID-19 is a potentially lethal infectious disease involving mainly the respiratory tract. The pandemic characteristic is related to constant mutations of the SARS-CoV-2 virus. Beside respiratory manifestations, multi-organ dysfunctions have been reported involving the central and the peripheral nervous system, the myocardium, the gastrointestinal tract, the tegument, the endocrine system, and the eye. With an estimated incidence between 6 and 12%, the concomitant viral infection of the ocular surface, presented as follicular conjunctivitis, ocular pain, ocular dryness, congestion, and discharge is the first and the most reported ocular manifestation. The incidence rises in children and in severe adult cases and can be accompanied by exposure keratitis and corneal ulcerations in ICU patients. Less frequent anterior segment manifestations include nodular scleritis, membranous conjunctivitis associated with major erythema multiforme, and anterior uveitis. Within the posterior segment of the eye, COVID 19 induces a ninefold increase of the risk for microvasculopathy characterized by retinal hemorrhages, cotton-wool spots, and capillary attenuation. Also, cases of acute macular neuropathy, arterial and venous retinal occlusions, and multifocal chorioretinitis were reported. Extraocular nerve palsies and inflammatory and ischemic optic neuropathies are neuro-ophthalmological consequences of the ischemic and inflammatory trouble. The usage of different COVID-19 vaccines has been also associated with different ocular manifestations ranging in severity from palpebral edema, purpuric and ecchymotic eyelid lesion to superior ophthalmic vein thrombosis, Tolosa-Hunt syndrome, venous and arterial retinal occlusions, acute macular neuropathy, paracentral acute middle maculopathy, anterior uveitis, neuroretinitis, and corneal graft rejection.<\/p>\n\n\n\n\n<p style=\"text-align: justify;\"><span style=\"color: #ff6600;\">Simpozion Alfasigma<\/span><\/p>\n\n\n\n\n<p style=\"text-align: justify;\"><span style=\"color: #ff6600;\">\u2018\u2019ROLUL SULODEXID IN AFECTIUNILE VASCULARE\u2018\u2019!\n\n\nLectori: A.O. Petri\u0219, D.C.\u00a0 Br\u0103ni\u0219teanu\n\n\n<\/span><span style=\"color: #ff6600;\"><\/span><\/p>\n\n\n\n\n<p style=\"text-align: justify;\">Boala venoasa cronica netratata poate avea o evolutie progresiva avand un impact semnificativ asupra calitatii vietii pacientilor.\n\n\nFactorii de risc ai bolii venoase impreuna cu stresul tensional, determina alterarea morfologica si functionala a glicocalixului endotelial si a endoteliului contribuind astfel la dezvoltarea bolii venoase.\n\n\nIn boala venoasa cronica hipertensiunea venoasa va activa tromboza, inflamatia parietala si remodelarea vasculara.\n\n\nTratamentul cu glicozaminoglicani (ex. Vessel Due F\u00ae \u2013 sulodexid original, considerat un precursor natural de glicocalix, un glicozaminoglican compozit 80% heparan-sulfat si 20% dermatan-sulfat) poate reface si mentine integritatea glicocalixului endotelial.<\/p>\n\n\n\n\n<p style=\"text-align: justify;\">Diabetul zaharat este o patologie care poate duce frecvent la complicatii microvasculare, precum picior diabetic, retinopatie diabetica si nefropatie diabetica (boala renala cronica), ca urmare a stresului chimic si metabolic generat de valorile crescute ale glicemiei asociate cresterii rezistentei tisulare la insulina.<\/p>\n\n\n\n\n<p style=\"text-align: justify;\">In cazul unui pacient cu retinopatie diabetica masurile terapeutice trebuie sa vizeze in primul rand eliminarea\/reducerea factorilor de risc, limitarea evolutiei leziunilor vasculare, ameliorarea hemodinamicii si refacerea structurii peretelui vascular.<\/p>\n\n\n\n\n<p style=\"text-align: justify;\">Tratamentul cu Vessel Due F\u00ae a inregistrat o crestere semnificativa a grosimii stratului de glicocalix masurat la nivelul vaselor retiniene, sustinand in acest fel caracterul vasculotrop marcant in refacerea endoteliului si a glicocalixului vascular, cu ameliorarea consecutiva a hemodinamicii si a functiei endoteliale.<\/p>\n\n\n\n\n<p style=\"text-align: justify;\">Untreated chronic venous disease can have a progressive evolution with a significant impact on patients\u2019 quality of life.\n\n\nThe risk factors of venous disease together with the tensional stress, determine the morphological and functional alteration of the endothelial glycocalyx and of the endothelium, thus contributing to the development of venous disease.\n\n\nIn chronic venous disease, venous hypertension will activate thrombosis, parietal inflammation, and vascular remodeling.\n\n\nTreatment with glycosaminoglycans (eg Vessel Due F\u00ae, considered a natural precursor of glycocalyx, a composite glycosaminoglycan 80% heparan sulfate and 20% dermatan sulfate) can restore and maintain the integrity of the endothelial glycocalyx.<\/p>\n\n\n\n\n<p style=\"text-align: justify;\">Diabetes is a condition that can frequently lead to microvascular complications, such as diabetic foot, diabetic retinopathy and diabetic nephropathy (chronic kidney disease), due to chemical and metabolic stress caused by high blood sugar levels associated with increased tissue resistance to insulin.<\/p>\n\n\n\n\n<p style=\"text-align: justify;\">In the case of a patient with diabetic retinopathy, the therapeutic measures must primarily aim at eliminating \/ reducing the risk factors, limiting the evolution of the vascular lesions, improving the hemodynamics and restoring the structure of the vascular wall.<\/p>\n\n\n\n\n<p style=\"text-align: justify;\">Vessel Due F\u00ae treatment proved a significant increase in the thickness of the glycocalyx layer measured in the retinal vessels, thus supporting the marked vasculotropism in the restoration of the endothelium and vascular glycocalyx, with the consequent improvement of hemodynamics and endothelial function.<\/p>\n\n\n\n\n<p style=\"text-align: justify;\">Keywords: original sulodexide, antithrombotic, chronic venous disease, diabetic retinopathy, microvascular complications, vascular lesions, endothelial function.<\/p>\n\n\n\n\n<p>--><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #ff6600;\">Scurt CV<\/span><\/p>\n<p style=\"text-align: justify;\"><strong>Titluri profesionale:<\/strong><br \/>\u2022 Conferen\u021biar \u015fi Titular de Curs la Disciplina Oftalmologie a Universit\u0103\u0163ii de Medicin\u0103 \u015fi Farmacie \u201dGrigore T. Popa\u201d Ia\u015fi<br \/>\u2022 Specialist \u00een Retinologie, \u015eeful Clinicii \u201dRetina Center\u201d Ia\u015fi, Rom\u00e2nia<br \/>\u2022 Membru fondator \u015fi membru \u00een Comitetul de Conducere a Societ\u0103\u0163ii Rom\u00e2ne Retina<br \/>\u2022 Membru \u00een Consiliul de conducere a Societ\u0103\u0163ii Rom\u00e2ne de Oftalmologie<br \/>\u2022 Titlu onorific de FEBO (Fellow of the European Board of Ophthalmology) acordat \u00een 2014 pentru merite profesionale \u015fi contribu\u0163ia adus\u0103 \u015fcolii de retinologie rom\u00e2ne\u015fti<br \/>\u2022 Editor Asistent \u015fi membru \u00een Comitetul Editorial Na\u0163ional al \u201cRomanian Journal of Ophthalmology\u201d<br \/>\u2022 Membru Euretina (European Society of Retina Specialists)<\/p>\n<p style=\"text-align: justify;\"><strong>Calific\u0103ri:<\/strong><br \/>\u2022 Titlu de Doctor Medic a Universit\u0103\u0163ii de Medicin\u0103 \u015fi Farmacie \u201dGrigore T Popa\u201d Ia\u015fi, 1991<br \/>\u2022 AFSA \u00een oftalmologie, specializarea retin\u0103, la Universitatea Claude Bernard, Lyon, France<br \/>\u2022 Medic primar oftalmolog din 2000<br \/>\u2022 Doctor \u00een \u0218tiin\u0163e Medicale din 2006 datorit\u0103 Lucr\u0103rii \u00een Retinologie<br \/>\u2022 Stagii de preg\u0103tire \u00een patologia medical\u0103 \u015fi chirurgical\u0103 a retinei \u00een departamente de specialitate din Lyon, Fran\u021ba; Louisville, SUA; Gent, Belgia; Frankfurt, Berlin \u015fi Wurzburg, Germania<\/p>\n<p style=\"text-align: justify;\"><strong>Contribu\u0163ii \u015ftiin\u0163ifice \u015fi profesionale:<\/strong><br \/>\u2022 Crearea primului centru de retin\u0103 medical\u0103, laser \u015fi chirurgical\u0103 \u00eentr-un spital public din zona Moldovei \u00een 1997<br \/>\u2022 Implicarea constant\u0103 \u00een promovarea \u015fi implementarea de noi metode diagnostice, tratamente medicale \u015fi chirurgicale \u00een patologia retinei<br \/>\u2022 Cooperare \u015ftiin\u0163ific\u0103 \u015fi implicare activ\u0103 \u00een 7 studii clinice interna\u0163ionale<br \/>\u2022 Peste 50 de articole \u015fi capitole de carte publicate<br \/>\u2022 Peste 150 de prezent\u0103ri \u015ftiin\u0163ifice la Congrese Na\u0163ionale \u015fi Interna\u0163ionale<br \/>\u2022 Speaker invitat la Conferin\u0163e \u015fi Congrese de specialitate<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; 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Univ. Dr. Br\u0103ni\u0219teanu Daniel ConstantinUniversitatea de Medicin\u0103 \u0219i Farmacie \u201cGrigore T. Popa\u201d Ia\u0219iClinica &#8220;Retina Center&#8221;, Ia\u0219i\u00a0 Scurt CV Titluri profesionale:\u2022 Conferen\u021biar \u015fi Titular de Curs la Disciplina Oftalmologie a Universit\u0103\u0163ii de Medicin\u0103 \u015fi Farmacie \u201dGrigore T. Popa\u201d Ia\u015fi\u2022 Specialist \u00een Retinologie, \u015eeful Clinicii \u201dRetina Center\u201d Ia\u015fi, Rom\u00e2nia\u2022 Membru fondator \u015fi membru \u00een Comitetul de [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":11296,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[12],"tags":[],"class_list":["post-8539","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lectori"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/posts\/8539","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/comments?post=8539"}],"version-history":[{"count":22,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/posts\/8539\/revisions"}],"predecessor-version":[{"id":12770,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/posts\/8539\/revisions\/12770"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/media\/11296"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/media?parent=8539"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/categories?post=8539"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/tags?post=8539"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}