{"id":9734,"date":"2023-02-14T13:52:09","date_gmt":"2023-02-14T11:52:09","guid":{"rendered":"https:\/\/primaderma.ro\/?page_id=9734"},"modified":"2023-03-30T16:07:04","modified_gmt":"2023-03-30T14:07:04","slug":"conf-univ-dr-anca-docea","status":"publish","type":"post","link":"https:\/\/pdi.ro\/2023\/conf-univ-dr-anca-docea\/","title":{"rendered":"Conf. Univ. Dr. Docea Anca"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; fullwidth=&#8221;on&#8221; disabled_on=&#8221;on|off|off&#8221; _builder_version=&#8221;4.19.4&#8243; custom_margin=&#8221;||&#8221; custom_padding=&#8221;15px||29px&#8221; top_divider_style=&#8221;waves2&#8243; top_divider_color=&#8221;#F0622A&#8221; top_divider_flip=&#8221;horizontal|vertical&#8221; bottom_divider_style=&#8221;waves2&#8243; bottom_divider_color=&#8221;#fcdedb&#8221; bottom_divider_height=&#8221;105px&#8221; bottom_divider_flip=&#8221;vertical&#8221; global_module=&#8221;9062&#8243; saved_tabs=&#8221;all&#8221; collapsed=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_fullwidth_header title=&#8221;@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF90aXRsZSIsInNldHRpbmdzIjp7ImJlZm9yZSI6IiIsImFmdGVyIjoiIn19@&#8221; disabled_on=&#8221;on|on|off&#8221; _builder_version=&#8221;4.19.4&#8243; _dynamic_attributes=&#8221;title&#8221; title_font=&#8221;Kaushan Script||||||||&#8221; title_text_align=&#8221;left&#8221; title_text_color=&#8221;#f0622a&#8221; title_font_size=&#8221;55px&#8221; content_font=&#8221;|600||on|||||&#8221; content_text_align=&#8221;center&#8221; content_text_color=&#8221;#686766&#8243; content_font_size=&#8221;15px&#8221; subhead_font=&#8221;||||||||&#8221; background_enable_color=&#8221;off&#8221; background_image=&#8221;https:\/\/pdi.ro\/2023\/wp-content\/uploads\/2022\/12\/PDI2023_header__-scaled.jpg&#8221; background_blend=&#8221;luminosity&#8221; background_layout=&#8221;light&#8221; custom_margin=&#8221;||-5px||false|false&#8221; custom_padding=&#8221;150px||150px||true|false&#8221; content_font_size_tablet=&#8221;&#8221; content_font_size_phone=&#8221;15px&#8221; content_font_size_last_edited=&#8221;on|desktop&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;2_5,3_5&#8243; _builder_version=&#8221;4.16&#8243; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;2_5&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_image src=&#8221;https:\/\/pdi.ro\/2023\/wp-content\/uploads\/2022\/04\/Anca-Docea-circle.png&#8221; title_text=&#8221;Anca Docea-circle&#8221; align=&#8221;center&#8221; align_tablet=&#8221;center&#8221; align_phone=&#8221;&#8221; align_last_edited=&#8221;on|desktop&#8221; _builder_version=&#8221;4.20.2&#8243; max_width=&#8221;25%&#8221; border_radii=&#8221;on|100px|100px|100px|100px&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][et_pb_column type=&#8221;3_5&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h4><span style=\"color: #ff6600;\"><strong><\/strong><\/span><\/h4>\n<h4><span style=\"color: #ff6600;\"><strong><\/strong><\/span><\/h4>\n<h4><span style=\"color: #ff6600;\"><strong><\/strong><\/span><\/h4>\n<h4><span style=\"color: #ff6600;\"><strong>Conf. Univ. Dr. Anca Oana Docea<\/strong><\/span><br \/><span style=\"color: #ff6600;\"><strong>Departamentul de toxicologie, Universitatea de Medicin\u0103 \u0219i Farmacie din Craiova, Craiova, Rom\u00e2nia<\/p>\n<p><\/strong><\/span><\/h4>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.16&#8243; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.20.2&#8243; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #ff6600;\">Parabenii \u2013 prieteni sau du\u0219man \u00een dermatologie?<\/span><\/p>\n<p><span style=\"color: #ff6600;\"> Autor: Anca Oana Docea<\/span><br \/>\nDepartamentul de toxicologie, Universitatea de Medicin\u0103 \u0219i Farmacie din Craiova, Craiova, Rom\u00e2nia<\/p>\n<p style=\"text-align: justify;\">Parabenii sunt esteri alchilici ai acidului p-hidroxibenzoic care sunt utiliza\u021bi ca conservan\u021bi \u00een multe produse de \u00eengrijire personal\u0103, produse farmaceutice \u0219i alimente datorit\u0103 activit\u0103\u021bii microbiene ridicate \u0219i lipofilit\u0103\u021bii. \u00cen ultimii ani, numeroase studii in vivo \u0219i in vitro au demonstrat poten\u021bialul estrogenic al acestor compu\u0219i \u0219i importan\u021ba lor \u00een apari\u021bia cancerului de s\u00e2n. Alte studii au legat expunerea la parabeni de activitatea antiandrogen\u0103 care afecteaz\u0103 negativ produc\u021bia de testosteron \u0219i fertilitatea. \u00cen\u021belegerea mecanismului prin care parabenii pot ac\u021biona ca substan\u021be chimice care perturb\u0103 sistemul endocrin la oameni este foarte important\u0103 pentru a minimiza riscul pe care aceste substan\u021be chimice \u00eel pot avea, deoarece pot contribui la o varietate de patologii, de la obezitate \u0219i diabet de tip 2 p\u00e2n\u0103 la afectarea functiei de reproducere, probleme de neurodezvoltare \u0219i cancere. P\u00e2n\u0103 \u00een prezent, autorit\u0103\u021bile de reglementare au ajuns la concluzia c\u0103 aceste substan\u021be chimice sunt considerate sigure pentru utilizare \u00een produse cosmetice \u0219i farmaceutice \u00een intervalul de doze recomandate. Av\u00e2nd \u00een vedere toate controversele pro \u0219i contra din jurul acestor substan\u021be, ar trebui s\u0103 se acorde mai mult\u0103 aten\u021bie utiliz\u0103rii lor \u00een produsele destinate unor grupuri speciale, cum ar fi nou-n\u0103scu\u021bii \u0219i femeile \u00eens\u0103rcinate.<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #ff6600;\">Parabens \u2013 friends or foe in dermatology?<\/span><\/p>\n<p><span style=\"color: #ff6600;\"> Author: Anca Oana Docea<\/span><br \/>\nDepartment of Toxicology, University of Medicine and Pharmacy of Craiova, Craiova, Romania<\/p>\n<p style=\"text-align: justify;\">Parabens are alkyl esters of p-hydroxybenzoic acid that are used as preservatives in many personal care products, pharmaceuticals, and foods due to their high microbial activity and lipophilicity. In recent years, numerous in vivo and in vitro studies have demonstrated the estrogenic potential of these compounds and their importance in the occurrence of breast cancer. Other studies linked paraben exposure to antiandrogenic activity that negatively affects testosterone production and fertility. Understanding the mechanism by which parabens can act as endocrine-disrupting chemicals in humans is very important to minimize the risk these chemicals can pose to humans, as they can contribute to a variety of health disorders, from obesity and type 2 diabetes to reproductive and neurodevelopmental problems and reproductive cancer. To date, regulators have concluded that these chemicals are considered safe for use in cosmetics and pharmaceuticals within the recommended dose range. Given all the pros and con controversies surrounding these chemicals, more attention should be paid to their use in products intended for special groups such as newborns and pregnant women.<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #ff6600;\">Scurt CV<\/span><\/p>\n<p style=\"text-align: justify;\">Dr. Anca Oana Docea este o farmacist\u0103 specializat\u0103 \u00een Farmacologie Clinic\u0103 \u0219i de\u021bine un masterat \u00een Farmacologie \u0219i Toxicologie. Din ianuarie 2018, de\u021bine titlul de ERT (European Chemical Agency). Este reprezentanta Rom\u00e2niei \u00een Comitetul pentru Evaluarea Riscurilor Chimicale de la Agen\u021bia European\u0103 pentru Produse Chimice (ECHA). Teza sa de doctorat a fost realizat\u0103 pe tema \u201eImplica\u021biile patogenice ale factorilor de cre\u0219tere EGF \u0219i TGF, precum \u0219i ale receptorilor lor, \u00een cazul carcinomelor gastrice\u201d. Dr. Docea s-a specializat \u00een teste de toxicologie animal\u0103 in vivo, teste neurocomportamentale, analize biochimice \u0219i imunohistochimice. \u00cen ultimii ani, cercetarea sa s-a axat pe nanotoxicologie \u0219i evaluarea siguran\u021bei de transportatori nanometrici amfifilici din poli-N-vinil-2-pirolidon\u0103 \u0219i studii de toxicitate de lung\u0103 durat\u0103 la doze sc\u0103zute, simul\u00e2nd expunerea la via\u021ba real\u0103. De asemenea, s-a specializat \u00een toxicologie clinic\u0103 la Departamentul de Toxicologie al Facult\u0103\u021bii de Medicin\u0103 din cadrul Universit\u0103\u021bii Aristotel din Salonic, metode de analiz\u0103 a seturilor de date de transcriptom folosind metode informatice la King&#8217;s College London, Facultatea de \u0218tiin\u021be \u0219i Medicin\u0103, Departamentul de Genetic\u0103 Medical\u0103 \u0219i Molecular\u0103, precum \u0219i \u00een noi modele de evaluare a neurotoxicit\u0103\u021bii xenobioticelor la Departamentul de Farmacologie Molecular\u0103 de la Albert Einstein College of Medicine, din New York, SUA. \u00cen prezent, este conferen\u021biar universitar habilitat \u00een Departamentul de Toxicologie din cadrul Universit\u0103\u021bii de Medicin\u0103 \u0219i Farmacie din Craiova, Facultatea de Farmacie. A publicat peste 100 de articole indexate \u00een jurnalele Web of Science \u0219i are un indice h de 42 (Clarivate Analytics). \u00cen ultimii ani, Dr. Docea a c\u00e2\u0219tigat peste 50 de premii de la UEFISCDI (Executive Unit for Financing Higher Education, Research, Development and Innovation) pentru articolele publicate, iar \u00een 2022 a primit Premiul de Excelen\u021b\u0103 pentru Cercetare Farmaceutic\u0103 din partea Colegiului Farmaci\u0219tilor din Rom\u00e2nia. A condus trei proiecte de cercetare \u0219i cinci proiecte de mobilitate \u00een cercetare finan\u021bate de UEFISCDI.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.19.4&#8243; background_color=&#8221;rgba(240,98,42,0.19)&#8221; background_image=&#8221;https:\/\/pdi.ro\/2023\/wp-content\/uploads\/2022\/12\/PDI2023_header__-scaled.jpg&#8221; background_blend=&#8221;multiply&#8221; custom_padding=&#8221;54px|0px|0|0px|false|false&#8221; top_divider_style=&#8221;waves2&#8243; top_divider_color=&#8221;#ffffff&#8221; top_divider_height=&#8221;155px&#8221; top_divider_height_tablet=&#8221;&#8221; top_divider_height_phone=&#8221;97px&#8221; top_divider_height_last_edited=&#8221;on|desktop&#8221; bottom_divider_style=&#8221;waves2&#8243; bottom_divider_color=&#8221;#F0622A&#8221; bottom_divider_flip=&#8221;vertical&#8221; bottom_divider_height_tablet=&#8221;&#8221; bottom_divider_height_phone=&#8221;59px&#8221; 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submit_button_text=&#8221;Trimite mesajul&#8221; disabled_on=&#8221;off|off|off&#8221; _builder_version=&#8221;4.20.2&#8243; _unique_id=&#8221;794aaef5-e005-432a-99fb-9ca53e06d67b&#8221; title_font=&#8221;||||||||&#8221; custom_button=&#8221;on&#8221; button_text_color=&#8221;#F0622A&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_contact_field field_id=&#8221;Name&#8221; field_title=&#8221;Nume&#8221; _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221; button_text_size__hover_enabled=&#8221;off&#8221; button_one_text_size__hover_enabled=&#8221;off&#8221; button_two_text_size__hover_enabled=&#8221;off&#8221; button_text_color__hover_enabled=&#8221;off&#8221; button_one_text_color__hover_enabled=&#8221;off&#8221; button_two_text_color__hover_enabled=&#8221;off&#8221; button_border_width__hover_enabled=&#8221;off&#8221; button_one_border_width__hover_enabled=&#8221;off&#8221; button_two_border_width__hover_enabled=&#8221;off&#8221; button_border_color__hover_enabled=&#8221;off&#8221; 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field_title=&#8221;Mesajul dvs.&#8221; field_type=&#8221;text&#8221; fullwidth_field=&#8221;on&#8221; _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221; button_text_size__hover_enabled=&#8221;off&#8221; button_one_text_size__hover_enabled=&#8221;off&#8221; button_two_text_size__hover_enabled=&#8221;off&#8221; button_text_color__hover_enabled=&#8221;off&#8221; button_one_text_color__hover_enabled=&#8221;off&#8221; button_two_text_color__hover_enabled=&#8221;off&#8221; button_border_width__hover_enabled=&#8221;off&#8221; button_one_border_width__hover_enabled=&#8221;off&#8221; button_two_border_width__hover_enabled=&#8221;off&#8221; button_border_color__hover_enabled=&#8221;off&#8221; button_one_border_color__hover_enabled=&#8221;off&#8221; button_two_border_color__hover_enabled=&#8221;off&#8221; button_border_radius__hover_enabled=&#8221;off&#8221; button_one_border_radius__hover_enabled=&#8221;off&#8221; button_two_border_radius__hover_enabled=&#8221;off&#8221; button_letter_spacing__hover_enabled=&#8221;off&#8221; 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A. 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Univ. Dr. Anca Oana DoceaDepartamentul de toxicologie, Universitatea de Medicin\u0103 \u0219i Farmacie din Craiova, Craiova, Rom\u00e2nia Parabenii \u2013 prieteni sau du\u0219man \u00een dermatologie? Autor: Anca Oana Docea Departamentul de toxicologie, Universitatea de Medicin\u0103 \u0219i Farmacie din Craiova, Craiova, Rom\u00e2nia Parabenii sunt esteri alchilici ai acidului p-hidroxibenzoic care sunt utiliza\u021bi ca conservan\u021bi \u00een multe produse [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":11272,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[12],"tags":[],"class_list":["post-9734","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lectori"],"_links":{"self":[{"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/posts\/9734","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/comments?post=9734"}],"version-history":[{"count":14,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/posts\/9734\/revisions"}],"predecessor-version":[{"id":13035,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/posts\/9734\/revisions\/13035"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/media\/11272"}],"wp:attachment":[{"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/media?parent=9734"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/categories?post=9734"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pdi.ro\/2023\/wp-json\/wp\/v2\/tags?post=9734"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}