Professor Alun Davies
Prof. Dr. Krisztian Gaspar
Faculty of Medicine, University of Debrecen, Ungaria
Chronic inflammatory intestinal disorders in hidradenitis suppurativa
Krisztián Gáspár1,2,3, Károly Palatka4, Andrea Szegedi1,2,3
1Department of Dermatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary
2Doctoral School of Clinical Immunology and Allergology, University of Debrecen, Debrecen, Hungary
3ELKH-DE Allergology Research Group, Debrecen, Hungary
4Department of Gastroenterology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary
Hidradenitis suppurativa (HS) patients often experience gastrointestinal symptoms with possible chronic inflammatory intestinal disorders (CIID) in the background. The frequency of CIID in HS has not been investigated.
The pilot study was set to determine the occurrence of CIID in HS and characterise this population. Besides, the feasibility of fecal calprotectin (FC) test and anti-Saccharomyces cerevisiae antibody (ASCA) levels was investigated.
Newly diagnosed and untreated HS patients (n=74) arrived in the Department of Dermatology, University of Debrecen were referred to a gastroenterologist for FC followed by colonoscopy. C-reactive protein (CRP), white blood cell count, nucleotide-binding-oligomerisation-domain-containing-protein-2 (NOD2) polymorphism, and ASCA levels were measured. Patients were divided into HS-only and HS+CIID groups, based on the absence or presence of CIID. Laboratory and clinical parameters were compared in these groups.
The CIID frequency in HS was 28.4% (n=21/74), based on colonoscopy and histology. Significantly more patients had severe disease in the HS+CIID group compared with the HS-only group, and BMI was significantly lower in the HS+CIID group (28.20±5.58 vs. 32.74±6.45, p=0.006). FC positivity occurred significantly more (90.48% vs. 3.77%, p<0.001), and ASCA IgG levels were significantly elevated (22.08±23.07 vs 8.41±10.94 U/mL, p=0.001) in HS+CIID patients compared with HS-only patients. FC test identified HS+CIID patients with high specificity and sensitivity.
In conclusion, a high frequency of CIID was detected in the examined HS population. The non-invasive FC test has high sensitivity and specificity for diagnosing CIID in HS patients. Concomitant CIID and HS may indicate the need to start early biological treatment.
Krisztian Gaspar, MD, PhD is graduated in 2000 at the University of Debrecen Medical School, Debrecen, Hungary.
He is a board certified (1) dermato-venereologist, (2) allergologist-clinical immunologist and (3) clinical pharmacologist.
He is an assistant professor at the Dept. of Dermatology and Dept. of Dermatological Allergology of the University of Debrecen, in Debrecen, Hungary.
His main research interests are psoriasis and atopic dermatitis (AD). He defended his academic degree (PhD) by his research completed on the regulative T cell impairment and remodelling in AD. With international scholarships he extended his clinical and research experience abroad, by spending two years in Germany (Düsseldorf, Kassel, Frankfurt) and in the UK (London).
He is a working member of 5 international dermatological societies.
He has spoken and presented lectures or posters in over 25 international conferences.
He published over 80 papers in national and international journals and 6 book chapters. His cumulative impact factor is over 185, Hirsch index is 16, and total citation is over 700.
For his work he has been awarded by EADV (Leadership Development Initiative Scholarship), ESDR (Research Fellow Award), ILDS (Young Dermatologist International Achievement Award), AAD (Annual Meeting Poster Exhibit Scholarship) and ISDS (Perry Robins Scholarship Award).
Prof.Dr. Heim Dominik
General surgeon and venous specialist at the Venenzentrum in Thun, Switzerland, and the president of the EVF in 2019–2020
Honey and «more than honey» in the treatment of chronic wounds
Author: Dominik Heim
In 2022 I said a few words of the use of honey in the treatment of wounds/ chronic wounds. In a more elaborate way I’ll present the effect and assumed working mechanism of honey and its use in all kind of wounds this year. There is a difference between honey to eat and honey to treat! And if honey is not enough, an alternative is still at hands: the use of bee-venom, administrated by real bee-stings! A technique known for many centuries, nearly forgotten and still very effective with amazing results.
Venoactive drugs/ VAD – when does ist make sense to use them
Author: Dominik Heim
Venoactive drugs have several effects that are beneficial in the treatment of varicose veins – especially in the C6 class (CEAP classification). The knowledge on these medicaments/ drugs is still not well spread and its use in several countries is limited.
What is their role in chronic venous disease/CVD? How do they work? How to choose among the variety of these drugs?
In this talk VAD’s are explained and clinical cases with a successful use are presented. A look into the future will demonstrate their use even to counteract and to treat postthrombotic syndrome/ PTS – VAD: a promise into the future !
Born in Zürich, Switzerland, 28th August 1949
Graduated at the University of Basel, Switzerland, June 1977
Postgraduate trainings at different institutions in Switzerland and England
Surgeon-in-chief at the Hospital of Frutigen, Switzerland, 1995-2014
Since 1st September 2014
– surgical consultant at the Venous Centre, clinic Hohmad, Thun, CH
– member of the Medical Insurance Competence-team at lexiatrik, Lucerne, CH
– GP at the Medical Center Arosa, CH
Scientific appointments: PD (Privatdozent)/ Lecturer at the University of Basel
Board member of
-Swiss society for phlebology, SGP
-European Venous Forum, EVF
-Swiss Society for Traumatology and Insurance Medicine, SGTV
-European Society for Trauma and Emergency Surgery, ESTES
-société internationale de traumatologie du ski et médecine des sports d’hiver
Honorary member of:
– Swiss society for surgery, SGC
-Swiss society for general surgery and traumatology, SGACT
-European Society for trauma and emergency Surgery, ESTES
Actual committements: Annual phlebological workshops in Thun, Invited lecturer to phlebological and traumatological congresses, insurance medicine, GP
Married to Simone Heim-Lamezan. Four children: Corsin (34), Mevion (32), Vital (30) and Neira (25). Lives with his family in Frutigen, Bernese Oberland, Switzerland
Prof. Dr. Manfred Herold
Medical University of Innsbruck, Austria
Prof. Dr. Rene Milleret
Clinica Venart, Cluj-Napoca, România
Membru al Academiei Naționale de Chirurgie
Prof. Dr. Khusrow Niazi
Member, American College of Cardiology Competency Management Committee
Professor of Medicine, Emory University, Atlanta, Georgia
Dr. Niazi is board certified in Internal Medicine, Cardiovascular Diseases and Interventional Cardiology by the American Board of Internal Medicine. In addition he is certified in Vascular Medicine Board and in Endovascular Board by the American Board of Vascular Medicine. He has had extensive experience working in some of the leading institutions of the world including USA. He was the first physician who conducted a prospective trial of small vessel stenting was superior to balloon angioplasty in coronary arteries. He joined Emory University in 2003. He has trained many cardiologists and has done mini-seminars in how to do and read non-invasive Doppler techniques for the diagnosis of vascular diseases and complex interventional procedures. He has written two book chapters in Interventional Cardiology 2nd edition on PAD and chronic venous disease. He has pushed cardiologists to look for vascular disease outside the heart. Dr. Niazi is a prolific teacher and besides teaching medical students, residents and cardiology fellows, he has been invited to give lectures, grand rounds locally, nationally and internationally. He has done live demonstration cases demonstrating various endovascular techniques in different countries. He enjoys working with other physicians and learning from them.